Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Akemi Katsurada"'
Autor:
Xiao Chun Li, Rumana Hassan, Ana Paula O. Leite, Akemi Katsurada, Courtney Dugas, Ryosuke Sato, Jia Long Zhuo
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 24, p 15798 (2022)
The roles of angiotensin II (Ang II) AT1 (AT1a) receptors and its downstream target Na+/H+ exchanger 3 (NHE3) in the proximal tubules in the development of two-kidney, 1-clip (2K1C) Goldblatt hypertension have not been investigated previously. The pr
Externí odkaz:
https://doaj.org/article/942c37f785704ac389f78aeae4aac122
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 14, p 7680 (2022)
Augmentation of intrarenal angiotensinogen (AGT) leads to further formation of intrarenal angiotensin II (Ang II) and the development of hypertensive kidney injury. Recent studies demonstrated that macrophages and the enhanced production of pro-infla
Externí odkaz:
https://doaj.org/article/d068b364246243b98bc9234ed724f5bd
Autor:
Christophe Hansen-Estruch, Mohamed H. Bikhet, Mariyam Javed, Akemi Katsurada, Ryousuke Satou, Weijian Shao, David Ayares, Raman Venkataramanan, David K.C. Cooper, Eric Judd, Luis Gabriel Navar
Publikováno v:
American Journal of Transplantation. 23:353-365
Autor:
Jia Zhuo, Rumana Hassan, Akemi Katsurada, Courtney Dugas, Ryosuke Sato, Jian-Xiong Chen, Xiao Li
Publikováno v:
Physiology. 38
We have recently demonstrated two functional angiotensin II (Ang II)/ Agtr1a/O2- and Ang II/ Agtr2/NO/cGMP signaling pathways in the mitochondria of the proximal tubules of the kidney. Sirtuin 3 (Sirt3) is a major NAD-dependent deacetylase in the mit
Autor:
Courtney M Dugas, Samir S. El-Dahr, Stacy M Yanofsky, Jiao Liu, Ryousuke Satou, Akemi Katsurada, Zubaida Saifudeen
Publikováno v:
Am J Physiol Renal Physiol
Human kidney organoid technology holds promise for novel kidney disease treatment strategies and utility in pharmacological and basic science. Given the crucial roles of the intrarenal renin-angiotensin system (RAS) and angiotensin II (ANG II) in the
Autor:
Ryousuke Satou, Dien Ye, Hong S Lu, Akemi Katsurada, Courtney M Dugas, Alan Daugherty, Shahriar Motazedian, L G Navar
Publikováno v:
Hypertension. 79
Regulation of systemic and local angiotensinogen (AGT) levels is a key determinant of tissue angiotensin II (Ang II) levels and inappropriate AGT augmentation promotes the development of hypertension and tissue injury. Kidney and urinary AGT levels a
Autor:
L. G. Navar, Christophe Hansen‐Estruch, Mohamed H. Bikhet, Mariyam Javed, Akemi Katsurada, Ryousuke Satou, Weijian Shao, David Ayares, David K. C. Cooper, Eric Judd
Publikováno v:
The FASEB Journal. 36
Autor:
Michael W. Cypress, Ryousuke Satou, Courtney M Dugas, L. Gabriel Navar, Akemi Katsurada, T. Cooper Woods, Vivian Fonseca
Publikováno v:
Am J Physiol Renal Physiol
Renal proximal tubular angiotensinogen (AGT) is increased by hyperglycemia (HG) in diabetes mellitus, which augments intrarenal angiotensin II formation, contributing to the development of hypertension and kidney injury. Sodium-glucose cotransporter
Autor:
Akemi Katsurada, Ryousuke Satou, Vivian Fonseca, Kayoko Miyata, Courtney M Dugas, L. Gabriel Navar, T. Cooper Woods, Natasha C Klingenberg
Publikováno v:
American Journal of Nephrology. 49:331-342
Background: Hypertension and renal injury are common complications of type 2 diabetes mellitus (T2DM). Hyperglycemia stimulates renal proximal tubular angiotensinogen (AGT) expression via elevated oxidative stress contributing to the development of h
Advanced Glycation End Products Stimulate Angiotensinogen Production in Renal Proximal Tubular Cells
Autor:
Kayoko Miyata, Ryousuke Satou, Joseph M. Garagliano, Andrea Zsombok, Akemi Katsurada, Andrei V. Derbenev, L. Gabriel Navar
Publikováno v:
The American Journal of the Medical Sciences. 357:57-66
Background Elevated advanced glycation end products (AGE) in diabetes mellitus (DM) are implicated in the progression of DM-associated tissue injury, including diabetic nephropathy. The intrarenal renin-angiotensin system, in particular augmentation