Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Akemi, Nishigaki"'
Autor:
Akemi Nishigaki, Takeharu Kido, Naoko Kida, Maiko Kakita‐Kobayashi, Hiroaki Tsubokura, Yoji Hisamatsu, Hidetaka Okada
Publikováno v:
Reproductive Medicine and Biology, Vol 19, Iss 2, Pp 189-197 (2020)
Abstract Purpose Resveratrol is a well‐known potent activator of sirtuin‐1 (SIRT1). We investigated the direct effects of hypoxia and resveratrol on SIRT1/ peroxisome proliferator‐activated receptor‐gamma coactivator 1α (PGC‐1α) pathways,
Externí odkaz:
https://doaj.org/article/db9fb0051ebf440b86bcfc05d0033395
Autor:
Akemi Nishigaki, Hiroaki Tsubokura, Mitsuaki Ishida, Yoshiko Hashimoto, Aya Yoshida, Yoji Hisamatsu, Tomoko Tsuzuki‐Nakao, Hiromi Murata, Hidetaka Okada
Publikováno v:
Reproductive Medicine and Biology, Vol 21, Iss 1, Pp n/a-n/a (2022)
Abstract Purpose N‐myc downstream‐regulated gene 1 (NDRG1) is expressed in various human tissues and plays a role in regulating cellular proliferation, angiogenesis, and hypoxia sensing. However, the role of NDRG1 in the ovary remains poorly unde
Externí odkaz:
https://doaj.org/article/063391346ab647a69ef50f7b68332f0c
Publikováno v:
Reproductive Medicine and Biology, Vol 21, Iss 1, Pp n/a-n/a (2022)
Abstract Background Ovarian function is closely related to the degree of vascular network development surrounding the ovary. Maternal aging‐related construction defects in this vascular network can cause ovarian hypoxia, which impedes oocyte nutrie
Externí odkaz:
https://doaj.org/article/8cf3ebf08cc34cffa9880eeee89f05a2
Autor:
Akemi Nishigaki, Tomoko Tsuzuki‐Nakao, Takeharu Kido, Naoko Kida, Maiko Kakita‐Kobayashi, Hiromi Murata, Hidetaka Okada
Publikováno v:
Reproductive Medicine and Biology, Vol 18, Iss 2, Pp 161-166 (2019)
Abstract Purpose To study the association between stromal cell‐derived factor‐1 (SDF‐1/CXCL12) and vascular endothelial growth factor (VEGF) concentrations in individual human ovarian follicles and IVF outcomes. Methods Concentrations of SDF‐
Externí odkaz:
https://doaj.org/article/f4faeea7c17f48deb39f886ff035556c
Autor:
Takeharu Kido, Hiromi Murata, Akemi Nishigaki, Hiroaki Tsubokura, Shinnosuke Komiya, Naoko Kida, Maiko Kakita-Kobayashi, Yoji Hisamatsu, Tomoko Tsuzuki, Yoshiko Hashimoto, Hidetaka Okada
Publikováno v:
Heliyon, Vol 6, Iss 6, Pp e03985- (2020)
Aim: The study aimed to elucidate the glycolytic metabolism of human endometrial stromal cells (hESCs) in hypoxic environment. Main methods: The hESCs were cultured in hypoxic environment, and their metabolic pathways were analyzed using metabolomics
Externí odkaz:
https://doaj.org/article/6dd5fb80c4e64558900deeb59ae9d4aa
Autor:
Hiroaki, Tsubokura, Mitsuaki, Ishida, Akemi, Nishigaki, Takuya, Yokoe, Shinnosuke, Komiya, Yusuke, Butsuhara, Aya, Yoshida, Yoji, Hisamatsu, Yoshiko, Hashimoto, Tomoko, Tsuzuki-Nakao, Hiromi, Murata, Koji, Tsuta, Hidetaka, Okada
Publikováno v:
Molecular Medicine Reports. 27
Preeclampsia, characterized by high blood pressure and proteinuria during pregnancy, causes serious complications in both the mother and the fetus. Although there have been several studies on the causes of preeclampsia, the detailed mechanism of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eed7a4a571e0c7d8e22fe89b9b03fe8a
https://doi.org/10.3892/mmr.2022.12905
https://doi.org/10.3892/mmr.2022.12905
Autor:
Akemi Nishigaki, Hiroaki Tsubokura, Mitsuaki Ishida, Yoshiko Hashimoto, Aya Yoshida, Yoji Hisamatsu, Tomoko Tsuzuki‐Nakao, Hiromi Murata, Hidetaka Okada
Publikováno v:
Reproductive medicine and biology. 21(1)
N-myc downstream-regulated gene 1 (NDRG1) is expressed in various human tissues and plays a role in regulating cellular proliferation, angiogenesis, and hypoxia sensing. However, the role of NDRG1 in the ovary remains poorly understood. Therefore, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::681843deda1fb4f9ae9315ed62454246
https://pubmed.ncbi.nlm.nih.gov/35386369
https://pubmed.ncbi.nlm.nih.gov/35386369
Autor:
Tomoko Tsuzuki, Naoko Kida, Yoji Hisamatsu, Hiromi Murata, Hiroaki Tsubokura, Yoshiko Hashimoto, Akemi Nishigaki, Hidetaka Okada, Shinnosuke Komiya, Takeharu Kido, Maiko Kakita-Kobayashi
Publikováno v:
Heliyon, Vol 6, Iss 6, Pp e03985-(2020)
Heliyon
Heliyon
Aim The study aimed to elucidate the glycolytic metabolism of human endometrial stromal cells (hESCs) in hypoxic environment. Main methods The hESCs were cultured in hypoxic environment, and their metabolic pathways were analyzed using metabolomics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::892bedb40a0fa612ac42b08cd886aef3
http://www.sciencedirect.com/science/article/pii/S2405844020308306
http://www.sciencedirect.com/science/article/pii/S2405844020308306
Autor:
Kiichi Hirota, Naoko Kida, Hiromi Murata, Yoshiko Hashimoto, Yoshiyuki Matsuo, Akemi Nishigaki, Tomoko Tsuzuki-Nakao, Maiko Kakita-Kobayashi, Shinnosuke Komiya, Hiroaki Tsubokura, Hidetaka Okada, Hidemasa Bono, Takeharu Kido
Publikováno v:
Endocrinology. 161(6)
Endometrial stromal cells differentiate into decidual cells through the process of decidualization. This differentiation is critical for embryo implantation and the successful establishment of pregnancy. Recent epidemiological studies have suggested
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f090f50228599825e098011a712f63c
https://pubmed.ncbi.nlm.nih.gov/32242219
https://pubmed.ncbi.nlm.nih.gov/32242219
Autor:
Akemi Nishigaki, Kayo Shimoi, Tomoko Tsuzuki, Hideharu Kanzaki, Hidetaka Okada, Hisayuu Shindoh
Publikováno v:
Gynecological Endocrinology. 32:323-328
Recent evidence points to a possible role for hypoxia-inducible factor (HIF)-1 in the pathogenesis and development of endometriosis. The objectives of this study were to investigate the critical role of HIF-1 in endometriosis and the effect of the HI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c58a81f7232ec27fcb1ad22bfae6b75
https://doi.org/10.3109/09513590.2015.1121225
https://doi.org/10.3109/09513590.2015.1121225