Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Akeila Bellahcène"'
Autor:
Marie-Julie Nokin, Florence Durieux, Paul Peixoto, Barbara Chiavarina, Olivier Peulen, Arnaud Blomme, Andrei Turtoi, Brunella Costanza, Nicolas Smargiasso, Dominique Baiwir, Jean L Scheijen, Casper G Schalkwijk, Justine Leenders, Pascal De Tullio, Elettra Bianchi, Marc Thiry, Koji Uchida, David A Spiegel, James R Cochrane, Craig A Hutton, Edwin De Pauw, Philippe Delvenne, Dominique Belpomme, Vincent Castronovo, Akeila Bellahcène
Publikováno v:
eLife, Vol 13 (2024)
Externí odkaz:
https://doaj.org/article/dfea8585ba3b4458899254c8dcbe41ae
Autor:
Sandy Anania, Martin Farnir, Raphaël Peiffer, Yasmine Boumahd, Marc Thiry, Ferman Agirman, Naima Maloujahmoum, Akeila Bellahcène, Olivier Peulen
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-21 (2024)
Abstract Background Pancreatic ductal adenocarcinoma is an aggressive cancer type with one of the lowest survival rates due to late diagnosis and the absence of effective treatments. A better understanding of PDAC biology will help researchers to dis
Externí odkaz:
https://doaj.org/article/2c3de2fc53ca463d819c6e9484a4e942
Autor:
Gaurav Dube, Assia Tiamiou, Martin Bizet, Yasmine Boumahd, Imène Gasmi, Rebekah Crake, Justine Bellier, Marie-Julie Nokin, Emilie Calonne, Rachel Deplus, Tom Wissocq, Olivier Peulen, Vincent Castronovo, François Fuks, Akeila Bellahcène
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-18 (2023)
Abstract Background Aerobic glycolysis, also known as the Warburg effect, is predominantly upregulated in a variety of solid tumors, including breast cancer. We have previously reported that methylglyoxal (MG), a very reactive by-product of glycolysi
Externí odkaz:
https://doaj.org/article/99203b58e323473ab885bd1de0fe091d
Autor:
Gilles Rademaker, Brunella Costanza, Justine Bellier, Michael Herfs, Raphaël Peiffer, Ferman Agirman, Naïma Maloujahmoum, Yvette Habraken, Philippe Delvenne, Akeila Bellahcène, Vincent Castronovo, Olivier Peulen
Publikováno v:
Oncogenesis, Vol 12, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/3c391d5f130d4134b472946773f3313a
Autor:
Gilles Rademaker, Brunella Costanza, Sébastien Pyr dit Ruys, Raphaël Peiffer, Ferman Agirman, Naïma Maloujahmoum, Didier Vertommen, Andrei Turtoi, Akeila Bellahcène, Vincent Castronovo, Olivier Peulen
Publikováno v:
Oncogenesis, Vol 11, Iss 1, Pp 1-10 (2022)
Abstract Introduction Colorectal cancer remains a public health issue and most colon cancer patients succumb to the development of metastases. Using a specific protocol of pressure-assisted interstitial fluid extrusion to recover soluble biomarkers,
Externí odkaz:
https://doaj.org/article/5b80583472704744baf80c789846d166
Autor:
Gilles Rademaker, Yasmine Boumahd, Raphaël Peiffer, Sandy Anania, Tom Wissocq, Maude Liégeois, Géraldine Luis, Nor Eddine Sounni, Ferman Agirman, Naïma Maloujahmoum, Pascal De Tullio, Marc Thiry, Akeila Bellahcène, Vincent Castronovo, Olivier Peulen
Publikováno v:
Redox Biology, Vol 53, Iss , Pp 102324- (2022)
Myoferlin, an emerging oncoprotein, has been associated with a low survival in several cancer types including pancreas ductal adenocarcinoma where it controls mitochondria structure and respiratory functions. Owing to the high susceptibility of KRAS-
Externí odkaz:
https://doaj.org/article/825b81d9bde840298a5b3b5ded7cf2a2
Autor:
Rebekah Crake, Imène Gasmi, Jordan Dehaye, Fanny Lardinois, Raphaël Peiffer, Naïma Maloujahmoum, Ferman Agirman, Benjamin Koopmansch, Nicky D’Haene, Oier Azurmendi Senar, Tatjana Arsenijevic, Frédéric Lambert, Olivier Peulen, Jean-Luc Van Laethem, Akeila Bellahcène
Publikováno v:
Cells, Vol 12, Iss 10, p 1414 (2023)
Pancreatic ductal adenocarcinoma (PDAC) is a fatal disease with poor prognosis. Gemcitabine is the first-line therapy for PDAC, but gemcitabine resistance is a major impediment to achieving satisfactory clinical outcomes. This study investigated whet
Externí odkaz:
https://doaj.org/article/783f0eb541c3480e8e03caf7a479f4db
Autor:
Géraldine Luis, Adrien Godfroid, Shin Nishiumi, Jonathan Cimino, Silvia Blacher, Erik Maquoi, Coline Wery, Alice Collignon, Rémi Longuespée, Laetitia Montero-Ruiz, Isabelle Dassoul, Naima Maloujahmoum, Charles Pottier, Gabriel Mazzucchelli, Edwin Depauw, Akeila Bellahcène, Masaru Yoshida, Agnès Noel, Nor Eddine Sounni
Publikováno v:
Redox Biology, Vol 43, Iss , Pp 102006- (2021)
Problem: Tumor recurrence is a major clinical issue that represents the principal cause of cancer-related deaths, with few targetable common pathways. Mechanisms by which residual tumors persist and progress under a continuous shift between hypoxia-r
Externí odkaz:
https://doaj.org/article/3eb5ddbabbf94bec843e6e8d4acb98c3
Autor:
Marie-Julie Nokin, Justine Bellier, Florence Durieux, Olivier Peulen, Gilles Rademaker, Maude Gabriel, Christine Monseur, Benoit Charloteaux, Lieven Verbeke, Steven van Laere, Patrick Roncarati, Michael Herfs, Charles Lambert, Jean Scheijen, Casper Schalkwijk, Alain Colige, Jo Caers, Philippe Delvenne, Andrei Turtoi, Vincent Castronovo, Akeila Bellahcène
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-19 (2019)
Abstract Background Elevated aerobic glycolysis rate is a biochemical alteration associated with malignant transformation and cancer progression. This metabolic shift unavoidably generates methylglyoxal (MG), a potent inducer of dicarbonyl stress thr
Externí odkaz:
https://doaj.org/article/65d51f1a7dd24b1081a694086ad67b98
Autor:
Justine Bellier, Marie-Julie Nokin, Maurine Caprasse, Assia Tiamiou, Arnaud Blomme, Jean L. Scheijen, Benjamin Koopmansch, Gillian M. MacKay, Barbara Chiavarina, Brunella Costanza, Gilles Rademaker, Florence Durieux, Ferman Agirman, Naïma Maloujahmoum, Pino G. Cusumano, Pierre Lovinfosse, Hing Y. Leung, Frédéric Lambert, Vincent Bours, Casper G. Schalkwijk, Roland Hustinx, Olivier Peulen, Vincent Castronovo, Akeila Bellahcène
Publikováno v:
Cell Reports, Vol 30, Iss 5, Pp 1400-1416.e6 (2020)
Summary: The use of cetuximab anti-epidermal growth factor receptor (anti-EGFR) antibodies has opened the era of targeted and personalized therapy in colorectal cancer (CRC). Poor response rates have been unequivocally shown in mutant KRAS and are ev
Externí odkaz:
https://doaj.org/article/96932a30ac1e4a57b60f7bff8ef7fecf