Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Akbar M Siddiqui"'
Autor:
Cheri A Schaaf, Ziva Misulovin, Gurmukh Sahota, Akbar M Siddiqui, Yuri B Schwartz, Tatyana G Kahn, Vincenzo Pirrotta, Maria Gause, Dale Dorsett
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6202 (2009)
The cohesin protein complex was first recognized for holding sister chromatids together and ensuring proper chromosome segregation. Cohesin also regulates gene expression, but the mechanisms are unknown. Cohesin associates preferentially with active
Externí odkaz:
https://doaj.org/article/199cb84bcf8944dbb1f2cbbd80bbbd81
Autor:
Lei Zhao, Paul Whitehead, Lei Li, Mary Ellen Cvijic, Erica Cook, Akbar M. Siddiqui, Zhuyin Li, Darren Locke, Normand J. Cloutier, Dana E. Vanderwall, Youping Xiao, Larnie Myer, Holmes Derek A, Jia Peng, Richard W. Bishop, Shannon Hamilton
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-7 (2020)
Scientific Reports
Scientific Reports
Quantitatively determining in vivo achievable drug concentrations in targeted organs of animal models and subsequent target engagement confirmation is a challenge to drug discovery and translation due to lack of bioassay technologies that can discrim
Publikováno v:
Viruses, Vol 2, Iss 9, Pp 1918-1932 (2010)
The absence of herd immunity to orthopoxviruses and the concern that variola or monkeypox viruses could be used for bioterroristic activities has stimulated the development of therapeutics and safer prophylactics. One major limitation in this process
Externí odkaz:
https://doaj.org/article/08c1c16d5f5d4d2b967be153cfba6450
Autor:
William A. Banks, R. T. Kevorkian, H. J. Armbrecht, Akbar M. Siddiqui, Angela D. Mazza, M. J. Kim, Matthew T. Haren, Michael Green, Vijaya B. Kumar, M. J. Haas, John E. Morley
Publikováno v:
International Journal of Andrology. 34:55-68
Testosterone regulates energy metabolism and skeletal muscle mass in males, but the molecular mechanisms are not fully understood. This study investigated the response of skeletal muscle to castration and testosterone replacement in 8-week-old male m
Publikováno v:
Viruses, Vol 2, Iss 9, Pp 1918-1932 (2010)
Viruses
Viruses
The absence of herd immunity to orthopoxviruses and the concern that variola or monkeypox viruses could be used for bioterroristic activities has stimulated the development of therapeutics and safer prophylactics. One major limitation in this process
Autor:
William A. Banks, Susan A. Farr, Ping Patrick, Akbar M. Siddiqui, Gul N. Shah, H. J. Armbrecht, Michael Green, Vijaya B. Kumar, John E. Morley
Publikováno v:
Journal of Alzheimer's disease : JAD. 46(2)
The senescence-accelerated mouse (SAMP8) strain exhibits an age-related decrease in memory accompanied by an increase in hippocampal amyloid-β protein precursor (AβPP) and amyloid-β peptide (Aβ). We have shown that administration of an antisense
Autor:
Michael Green, Akbar M. Siddiqui, Susan A. Farr, William A. Banks, Ping Patrick, Gul N. Shah, Vijaya B. Kumar, John E. Morley, H. J. Armbrecht
Publikováno v:
Neurobiology of aging. 35(1)
The senescence-accelerated mouse (SAMP8) strain exhibits decreased learning and memory and increased amyloid beta (Aβ) peptide accumulation at 12 months. To detect differences in gene expression in SAMP8 mice, we used a control mouse that was a 50%
Autor:
Akbar M. Siddiqui, W. Michael Panneton, James D. Churchill, Carmine J. Coscia, Kuniyasu Ochiai, Victoria R. Rendell, Mariana M. Belcheva, Michael Green, Lubov A. Ezerskiy, Mayumi Miyatake, Kiyoshi Yamada, Alexi Kiss, Noriaki Koshikawa, Nicholas R. Crews, Hiroko Ikeda, Maureen J. Donlin, Andrew L. Leinweber
Publikováno v:
The Journal of biological chemistry. 285(49)
Opioid receptor signaling via EGF receptor (EGFR) transactivation and ERK/MAPK phosphorylation initiates diverse cellular responses that are cell type-dependent. In astrocytes, multiple μ opioid receptor-mediated mechanisms of ERK activation exist t
MORPHINE MODULATION OF THROMBSPONDIN LEVELS IN ASTROCYTES AND ITS IMPLICATIONS FOR SYNAPSE FORMATION
Autor:
Mayumi Miyatake, Alexi Kiss, Akbar M. Siddiqui, Noriaki Koshikawa, James H. Churchill, Mariana M. Belcheva, Luba Ezerskiy, W. Michael Panneton, Victoria R. Rendell, Michael Green, Andrew L. Leinweber, Hiroko Ikeda, Kiyoshi Yamada, Maureen J. Donlin, Kuniyasu Ochiai, Carmine J. Coscia
Publikováno v:
The FASEB Journal. 24
Autor:
Vincenzo Pirrotta, Maria Gause, Ziva Misulovin, Tatyana G. Kahn, Yuri B. Schwartz, Dale Dorsett, Cheri A. Schaaf, Gurmukh Sahota, Akbar M. Siddiqui
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6202 (2009)
PLoS ONE
PLoS ONE
The cohesin protein complex was first recognized for holding sister chromatids together and ensuring proper chromosome segregation. Cohesin also regulates gene expression, but the mechanisms are unknown. Cohesin associates preferentially with active