Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Akash K. George"'
Autor:
Akash K. George, Rubens P. Homme, Avisek Majumder, Anwesha Laha, Naira Metreveli, Harpal S. Sandhu, Suresh C. Tyagi, Mahavir Singh
Publikováno v:
International Journal of Ophthalmology, Vol 12, Iss 5, Pp 754-764 (2019)
AIM: To investigate the applications of hydrogen sulfide (H2S) in eye-specific ailments in mice. METHODS: Heterozygous cystathionine-β-synthase (CBS+/-) and wild-type C57BL/6J (WT) mice fed with or without high methionine diet (HMD) were administe
Externí odkaz:
https://doaj.org/article/c082792c7bf14bb2a1d914a5f0235ab5
Autor:
Mahavir Singh, Shanna J. Hardin, Akash K. George, Wintana Eyob, Dragana Stanisic, Sathnur Pushpakumar, Suresh C. Tyagi
Publikováno v:
Frontiers in Physiology, Vol 11 (2021)
Although a high-fat diet (HFD) induces gut dysbiosis and cardiovascular system remodeling, the precise mechanism is unclear. We hypothesize that HFD instigates dysbiosis and cardiac muscle remodeling by inducing matrix metalloproteinases (MMPs), whic
Externí odkaz:
https://doaj.org/article/893c54ef41434bd7811959192326505e
Autor:
Jack Molnar, Carissa Jo Mallonee, Dragana Stanisic, Rubens P. Homme, Akash K. George, Mahavir Singh, Suresh C. Tyagi
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Hidradenitis suppurativa (HS) is a chronic, inflammatory skin condition characterized by painful nodules which suppurate and later develop into scar tissues followed by the development of hypodermal tracts. Although the mechanisms behind HS are not f
Externí odkaz:
https://doaj.org/article/021b2315c3c14c2ebb05bf3ce5c2d946
Publikováno v:
Indian Journal of Neurosurgery, Vol 06, Iss 01, Pp 044-046 (2017)
Abstract The transsphenoidal approach to lesions of the sella turcica, especially for pituitary tumors, has been favored by neurosurgeons because of decreased perioperative patient morbidity and mortality of this approach compared with others. It is
Externí odkaz:
https://doaj.org/article/57877bdbc1c6415d80ec26eafd84b934
Autor:
Rubens P. Homme, Mahavir Singh, Avisek Majumder, Akash K. George, Kavya Nair, Harpal S. Sandhu, Neetu Tyagi, David Lominadze, Suresh C Tyagi
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Diabetic patients suffer from a host of physiological abnormalities beyond just those of glucose metabolism. These abnormalities often lead to systemic inflammation via modulation of several inflammation-related genes, their respective gene products,
Externí odkaz:
https://doaj.org/article/65f13a41b2bd4f528604309872ea9ef3
Publikováno v:
Indian Journal of Neurosurgery, Vol 05, Iss 01, Pp 059-060 (2016)
Abstract Incidence of tuberculosis (TB) is decreasing all over the world due to improved diagnosis and treatment. Though central nervous system TB accounts for 1% of all TB cases, it carries high mortality and neurologic morbidity. Surgery is difficu
Externí odkaz:
https://doaj.org/article/7c17aec4f7aa4753815c3ebe72e81553
Publikováno v:
Am J Pathol
This study investigated the effects of long-term NF-κB inhibition in mitigating retinal vasculopathy in a type 1 diabetic mouse model (Akita, Ins2(Akita)). Akita and wild-type (C57BL/6J) male mice, 24 to 26 weeks old, were treated with or without a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efc3c74d3ffbc9cd1b0f2c2aa1b653b2
https://doi.org/10.1016/j.ajpath.2021.01.016
https://doi.org/10.1016/j.ajpath.2021.01.016
Autor:
Neetu Tyagi, Mahavir Singh, Rubens P Homme, Akash K. George, Jyotirmaya Behera, Suresh C. Tyagi
Publikováno v:
Molecular Neurobiology
Traumatic brain injury (TBI) is a damage to the brain from an external force that results in temporary or permanent impairment in brain functions. Unfortunately, not many treatment options are available to TBI patients. Therefore, knowledge of the co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd87db2eee5c57c0b1d2119779fbc645
https://doi.org/10.1007/s12035-021-02357-2
https://doi.org/10.1007/s12035-021-02357-2
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 99:115-123
Hyperhomocysteinemia (HHcy) affects bone remodeling, since a destructive process in cortical alveolar bone has been linked to it; however, the mechanism remains at large. HHcy increases proinflammatory cytokines viz. TNF-α, IL-1b, IL-6, and IL-8 tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::650ded85666dfb377bec1e3aa4ebc357
https://doi.org/10.1139/cjpp-2020-0224
https://doi.org/10.1139/cjpp-2020-0224
Autor:
Dragana Stansic, Mahavir Singh, Rubens P Homme, Wintana Eyob, Akash K. George, Suresh C. Tyagi
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 99:56-63
Epigenetic DNA methylation (1-carbon metabolism) is crucial for gene imprinting/off-printing that ensures epigenetic memory but also generates a copious amount of homocysteine (Hcy), unequivocally. That is why during pregnancy, expectant mothers are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67f0482de0ff61cb6f1bbf5526b9dce6
https://doi.org/10.1139/cjpp-2020-0093
https://doi.org/10.1139/cjpp-2020-0093