Zobrazeno 1 - 10
of 200
pro vyhledávání: '"Akanksha Verma"'
Autor:
Isha Pahuja, Antara Ghoshal, Ahmed Abdallah Okieh, Akanksha Verma, Kriti Negi, Meetu Agarwal, Nidhi Subhash Chandra, Saurabh Kumar Sharma, Ashima Bhaskar, Ved Prakash Dwivedi
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 7 (2024)
ABSTRACT The host immune responses play a pivotal role in the establishment of long-term memory responses, which effectively aids in infection clearance. However, the prevailing anti-tuberculosis therapy, while aiming to combat tuberculosis (TB), als
Externí odkaz:
https://doaj.org/article/6099b1271ad74eb9bfa8b12dd780f110
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Mycobacterium tuberculosis (M.tb) effectively manipulates the host processes to establish the deadly respiratory disease, Tuberculosis (TB). M.tb has developed key mechanisms to disrupt the host cell health to combat immune responses and replicate ef
Externí odkaz:
https://doaj.org/article/30c3c1a13d9147c8ae0f4866abdecfff
Autor:
Isha Pahuja, Akanksha Verma, Antara Ghoshal, Suparba Mukhopadhyay, Anjna Kumari, Aishwarya Shaji, Shivam Chaturvedi, Ved Prakash Dwivedi, Ashima Bhaskar
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 4 (2023)
ABSTRACT Tuberculosis (TB) still tops the list of global health burdens even after COVID-19. However, it will sooner transcend the current pandemic due to the prevailing risk of reactivation of latent TB in immunocompromised individuals. The indiscri
Externí odkaz:
https://doaj.org/article/675b2b421b604bc2a35f8590c8d66e10
Autor:
Michael J. P. Crowley, Bhavneet Bhinder, Geoffrey J. Markowitz, Mitchell Martin, Akanksha Verma, Tito A. Sandoval, Chang-Suk Chae, Shira Yomtoubian, Yang Hu, Sahil Chopra, Diamile A. Tavarez, Paolo Giovanelli, Dingcheng Gao, Timothy E. McGraw, Nasser K. Altorki, Olivier Elemento, Juan R. Cubillos-Ruiz, Vivek Mittal
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
The IRE1α-XBP1 arm of the unfolded protein response (UPR) has been associated with immunosuppression and cancer progression. Here the authors show that IRE1α-XBP1 activation is associated with poor overall survival in patients with non-small cell l
Externí odkaz:
https://doaj.org/article/77b087499a044dd7be6eee31431dbce9
Autor:
Ashima Bhaskar, Isha Pahuja, Kriti Negi, Akanksha Verma, Antara Ghoshal, Babu Mathew, Gaurav Tripathi, Jaswinder Singh Maras, Shivam Chaturvedi, Ved Prakash Dwivedi
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106644- (2023)
Summary: Bacille Calmette-Guerin (BCG) generates limited long-lasting adaptive memory responses leading to short-lived protection against adult pulmonary tuberculosis (TB). Here, we show that host sirtuin 2 (SIRT2) inhibition by AGK2 significantly en
Externí odkaz:
https://doaj.org/article/b1a568ab7b094d5db897ff8de9f22986
Publikováno v:
Symmetry, Vol 15, Iss 9, p 1753 (2023)
This paper proposes an approximation algorithm based on the Legendre and Chebyshev artificial neural network to explore the approximate solution of fractional Lienard and Duffing equations with a Caputo fractional derivative. These equations show the
Externí odkaz:
https://doaj.org/article/2af5447bd7964f62946fd8e5ef743a2c
Autor:
Jacques Greenberg, Jessica Limberg, Akanksha Verma, David Kim, Xiang Chen, Yeon J. Lee, Maureen D. Moore, Timothy M. Ullmann, Jessica W. Thiesmeyer, Zachary Loewenstein, Kevin J. Chen, Caitlin E. Egan, Dessislava Stefanova, Rohan Bareja, Rasa Zarnegar, Brendan M. Finnerty, Theresa Scognamiglio, Yi-Chieh Nancy Du, Olivier Elemento, Thomas J. Fahey III, Irene M. Min
Publikováno v:
JCI Insight, Vol 7, Iss 23 (2022)
Pancreatic neuroendocrine tumors (PNETs) are malignancies arising from the islets of Langerhans. Therapeutic options are limited for the over 50% of patients who present with metastatic disease. We aimed to identify mechanisms to remodel the PNET tum
Externí odkaz:
https://doaj.org/article/6f96a988d4f44b32a06c2793e68c3f00
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Mycobacterium tuberculosis (M.tb) is an intracellular pathogen that predominantly affects the alveolar macrophages in the respiratory tract. Upon infection, the activation of TLR2 and TLR4- mediated signaling pathways leads to lysosomal degradation o
Externí odkaz:
https://doaj.org/article/b9344ba412a94423afc21d9a1241efb7
Autor:
Sara E. DiNapoli, Raúl Martinez-McFaline, Hao Shen, Ashley S. Doane, Alexendar R. Perez, Akanksha Verma, Amanda Simon, Isabel Nelson, Courtney A. Balgobin, Caitlin T. Bourque, Jun Yao, Renuka Raman, Wendy Béguelin, Jonathan H. Zippin, Olivier Elemento, Ari M. Melnick, Yariv Houvras
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Perturbations to the epigenome are known drivers of tumorigenesis. In melanoma, alterations in histone methyltransferases that catalyze methylation at histone 3 lysine 9 and histone 3 lysine 27—two sites of critical post-translational modification
Externí odkaz:
https://doaj.org/article/5d80517192864da19fb1b13a11e13c2e
Autor:
Andrew R. Marderstein, Manik Uppal, Akanksha Verma, Bhavneet Bhinder, Zakieh Tayyebi, Jason Mezey, Andrew G. Clark, Olivier Elemento
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Immune infiltration provides critical information for health and disease, yet it is unclear what factors influence infiltration levels. Here, the authors analyze human tissue transcriptomes from the Genotype-Tissue Expression project to find infiltra
Externí odkaz:
https://doaj.org/article/bdf1df0cbfa4438ab46ff62705e1237e