Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Akanksha Arvind"'
Autor:
Akanksha Arvind Sharma, Ashwani Kumar, Dinesh Kumar Pasi, Parth Dhamija, Gurleen Kaur Garry, Anshu Saini, Ruchi Jakhar
Publikováno v:
European Journal of Breast Health, Vol 20, Iss 1, Pp 15-18 (2024)
Objective: Mastalgia is the most common breast-related complaint. A multitude of hormonal changes and lifestyle associated factors have been implicated in its causation. A long list of treatment modalities have been tried with varying success rates.
Externí odkaz:
https://doaj.org/article/0926af1fca4e4ee8a48cce95c17e09d3
Autor:
Sharma, Akanksha Arvind1 akankshasharma199514@gmail.com, Kumar, Ashwani2, Pasi, Dinesh Kumar2, Dhamija, Parth2, Garry, Gurleen Kaur2, Saini, Anshu2, Jakhar, Ruchi2
Publikováno v:
European Journal of Breast Health. Jan2024, Vol. 20 Issue 1, p15-18. 4p.
Autor:
Des R. Richardson, Danuta S. Kalinowski, Akanksha Arvind, George Iskander, Sumit Sahni, Christian Stefani, Patric J. Jansson, Paul V. Bernhardt, Naresh Kumar, Zaklina Kovacevic, Maram T. Basha, Philip C. Sharpe, Zaynab Al-Eisawi, Darius J.R. Lane
Publikováno v:
Journal of Medicinal Chemistry. 59:294-312
Selenosemicarbazones show marked antitumor activity. However, their mechanism of action remains unknown. We examined the medicinal chemistry of the selenosemicarbazone, 2-acetylpyridine 4,4-dimethyl-3-selenosemicarbazone (Ap44mSe), and its iron and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db225eded9a3b183094eab39fed72dbd
https://doi.org/10.1021/acs.jmedchem.5b01399
https://doi.org/10.1021/acs.jmedchem.5b01399
Publikováno v:
Interdisciplinary Sciences: Computational Life Sciences. 5:296-311
Mycobacterium tuberculosis (Mtb) is a causative agent of tuberculosis (TB) disease, which has affected approximately 2 billion people worldwide. Due to the emergence of resistance towards the existing drugs, discovery of new anti-TB drugs is an impor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c967ef42ea37c166465227dd0fa171ad
https://doi.org/10.1007/s12539-013-0180-y
https://doi.org/10.1007/s12539-013-0180-y
Autor:
Tetsuo Yamagishi, Sumit Sahni, Akanksha Arvind, Danae M. Sharp, Patric J. Jansson, Des R. Richardson
Publikováno v:
Journal of Biological Chemistry. 288:31761-31771
Localization of the drug transporter P-glycoprotein (Pgp) to the plasma membrane is thought to be the only contributor of Pgp-mediated multidrug resistance (MDR). However, very little work has focused on the contribution of Pgp expressed in intracell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60b32c91ccfac386d7cd03ffa1ee3dbd
https://doi.org/10.1074/jbc.m113.514091
https://doi.org/10.1074/jbc.m113.514091
Autor:
Leslie W.-M. Fung, Jason R. Hickok, Chloe Antoniou, Sumit Sahni, Hong Shen, Akanksha Arvind, Douglas D. Thomas
Publikováno v:
Free Radical Biology and Medicine. 51:1558-1566
It is well established that nitric oxide ((•)NO) reacts with cellular iron and thiols to form dinitrosyliron complexes (DNIC). Little is known, however, regarding their formation and biological fate. Our quantitative measurements reveal that cellul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6ea46153647279edcd75964abbb1e70
https://doi.org/10.1016/j.freeradbiomed.2011.06.030
https://doi.org/10.1016/j.freeradbiomed.2011.06.030
Publikováno v:
Chemical Biology & Drug Design. 77:373-387
CCR3, a G protein-coupled receptor, plays a central role in allergic inflammation and is an important drug target for inflammatory diseases. To understand the structure-function relationship of CCR3 receptor, different computational techniques were e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f7cb9f116990127f9807352cc5a3e68
https://doi.org/10.1111/j.1747-0285.2011.01088.x
https://doi.org/10.1111/j.1747-0285.2011.01088.x
Publikováno v:
Journal of Molecular Modeling. 17:939-953
Despite the availability of effective chemotherapy and a moderately protective vaccine, new anti-tuberculosis agents are urgently needed to decrease the global incidence of tuberculosis (TB) disease. The MurB gene belongs to the bacterial cell wall b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85ee469b2a42c861de23f808bdbd1c23
https://doi.org/10.1007/s00894-010-0788-3
https://doi.org/10.1007/s00894-010-0788-3
Autor:
Danae M. Sharp, Alexandra E. Stacy, Sanaz Maleki, Des R. Richardson, Nicole A. Seebacher, Sumit Sahni, Tetsuo Yamagishi, Elaine Gutierrez, Akanksha Arvind, Patric J. Jansson
Publikováno v:
The Journal of biological chemistry. 290(15)
Background: There is a critical need for chemotherapeutics that overcome multidrug resistance (MDR). Results: Dp44mT is transported into the lysosome by Pgp, causing lysosomal targeting of Dp44mT and resulting in enhanced cytotoxicity in vitro and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2d3b809b03c43433fd0404a5c4146e2
https://pubmed.ncbi.nlm.nih.gov/25720491
https://pubmed.ncbi.nlm.nih.gov/25720491
Publikováno v:
Interdisciplinary sciences, computational life sciences. 4(3)
The cell wall of mycobacterium offers well validated targets which can be exploited for discovery of new lead compounds. MurC-MurF ligases catalyze a series of irreversible steps in the biosynthesis of peptidoglycan precursor, i.e. MurD catalyzes the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0e5e5a2b2d9639987079d73489f6fd3
https://pubmed.ncbi.nlm.nih.gov/23292696
https://pubmed.ncbi.nlm.nih.gov/23292696