Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Akang E. Ekpenyong-Akiba"'
Autor:
Michael E. Kelly, Marta Poblocka, Elena V. Piletska, Sergey A. Piletsky, Mohammad Althubiti, Gabriella Kocsis-Fodor, Akang E. Ekpenyong-Akiba, Justyna Janus, Francesco Canfarotta, Laura Castilla-Vallmanya, Salvador Macip, H Bashar Abd, Mireia Casulleras
Publikováno v:
Nanoscale Horizons. 4:757-768
The progressive accumulation of senescent cells in tissues in response to damage importantly contributes to pathophysiological conditions such as fibrosis, diabetes, cancer, Alzheimer's and ageing. Consistent with this, eliminating senescent cells pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::febbcc29647e01f4a120895eaa244825
https://doi.org/10.1039/c8nh00473k
https://doi.org/10.1039/c8nh00473k
Publikováno v:
Healthy Ageing and Longevity ISBN: 9783030449025
The clearance of senescent cells has the potential to become a therapeutic strategy that could be used in many pathologies, ranging from pulmonary fibrosis and diabetes to ageing itself. The initial genetic experiments performed in mouse models are n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98c340090d5c6a304043719de648a950
https://doi.org/10.1007/978-3-030-44903-2_6
https://doi.org/10.1007/978-3-030-44903-2_6
Autor:
Akang E. Ekpenyong-Akiba, Diana Jurk, Gabriella Kocsis-Fodor, Miran Rada, Yu Shi, Mohammad Althubiti, Sandra Germano, Marta Poblocka, Juan J. Canales, Salvador Macip
Publikováno v:
Aging Cell
One of the hallmarks of aging is the progressive accumulation of senescent cells in organisms, which has been proposed to be a contributing factor to age‐dependent organ dysfunction. We recently reported that Bruton's tyrosine kinase (BTK) is an up
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0951afaa37c55f93ad1e80ed0f7e8f0e
http://europepmc.org/articles/PMC6974713
http://europepmc.org/articles/PMC6974713
Autor:
Salvador Macip, Miran Rada, Akang E. Ekpenyong-Akiba, Koon-Guan Lee, Olga A. Fedorova, Kong-Peng Lam, Mohammad Althubiti, Nickolai A. Barlev
Publikováno v:
Oncotarget
p53 is a tumour suppressor that is activated in response to various types of stress. It is regulated by a complex pattern of over 50 different post-translational modifications, including ubiquitination by the E3 ligase MDM2, which leads to its protea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79cef52f4ac2dd5dd61907a131088f61
https://pubmed.ncbi.nlm.nih.gov/29290977
https://pubmed.ncbi.nlm.nih.gov/29290977