Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Akane Sada"'
Autor:
Yu Chen, Tatsuki Yamamoto, Yura Takahashi, Tomoka Moro, Tomoko Tajima, Yukiko Sakaguchi, Naoaki Sakata, Akihiko Yokoyama, Susumu Hijioka, Akane Sada, Yuko Tabata, Rieko Ohki
Publikováno v:
Cell Death and Disease, Vol 14, Iss 9, Pp 1-13 (2023)
Abstract Insulin signaling often plays a role in the regulation of cancer, including tumor initiation, progression, and response to treatment. In addition, the insulin-regulated PI3K-Akt-mTOR pathway plays an important role in the regulation of islet
Externí odkaz:
https://doaj.org/article/eb742293dced49c3a1be0d07a11e3fbf
Autor:
Yu Chen, Yura Takahashi, Tomoka Moro, Tomoko Tajima, Yukiko Sakaguchi, Tatsuki Yamamoto, Akihiko Yokoyama, Susumu Hijioka, Akane Sada, Yuko Tabata, Rieko Ohki
Insulin signaling often plays a role in the regulation of cancer including tumor initiation, progression, and response to treatment. In addition, the insulin-regulated PI3K-Akt-mTOR pathway plays an important role in the regulation of islet cell prol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d1f80e91226b481d59612493f2c2863
https://doi.org/10.1101/2022.10.21.507065
https://doi.org/10.1101/2022.10.21.507065
Autor:
Yuko Tabata, Kazuhiro Okumura, Akane Sada, Yu Chen, Kiyono Aoki, Masaki Fukuyo, Megumi Saito, Rieko Ohki, Atsushi Kaneda, Yuichi Wakabayashi
Publikováno v:
The Journal of investigative dermatology. 142(4)
Squamous cell carcinomas (SCCs) are one of the most frequent solid cancer types in humans and are derived from stratified epithelial cells found in various organs. SCCs derived from various organs share common important properties, including genomic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b88979ba56d823b9eee3374157f7881f
https://pubmed.ncbi.nlm.nih.gov/34592332
https://pubmed.ncbi.nlm.nih.gov/34592332
Autor:
Kiyono Aoki, Yuko Otani, Yuko Tabata, Aoze Su, Tomohiko Ohwada, Rieko Ohki, Akane Sada, Kouhei Tsumoto, Satoru Nagatoishi, Siyuan Wang
Publikováno v:
Chemical and Pharmaceutical Bulletin.
Protein-protein interactions (PPIs) are often mediated by helical, strand and/or coil secondary structures at the interface regions. We previously showed that non-naturally occurring, stable helical trimers of bicyclic β-amino acids (Abh) with all-t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::741174f4b36b4d27a9f219e315434418
https://doi.org/10.1248/cpb.c21-00238
https://doi.org/10.1248/cpb.c21-00238
Autor:
Yu Chen, Mayuna Shimada, Yutaka Suzuki, Issei Ezawa, Kisaburo Nagata, Masahiro Takikawa, Rieko Ohki, Atsushi Okabe, Yoko Yamaguchi, Tatsuya Kawase, Yuhei Takano, Akane Sada, Hiroyuki Aburatani, Shuichi Tsutsumi, Kentaro Semba
Publikováno v:
Cancer Science
The PHLDA family (pleckstrin homology-like domain family) of genes consists of 3 members: PHLDA1, 2, and 3. Both PHLDA3 and PHLDA2 are phosphatidylinositol (PIP) binding proteins and function as repressors of Akt. They have tumor suppressive function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::166364497426a6bb7d33f82db4ceb1ac
http://europepmc.org/articles/PMC6215895
http://europepmc.org/articles/PMC6215895
Autor:
Siyuan Wang, Luhan Zhai, Kentaro Yamaguchi, Akane Sada, Aoze Su, Rieko Ohki, Masayuki Nara, Masatoshi Kawahata, Tomohiko Ohwada, Yuko Otani
Publikováno v:
Organic letters. 21(19)
Our NMR, IR/Raman, CD spectroscopic, and X-ray crystallographic studies, as well as accelerated molecular dynamics simulations, showed that alternating hybrid α/β-peptides containing a bicyclic β-proline surrogate form unique extended curved folds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2867eca331072f56b276b1f86ca45332
https://pubmed.ncbi.nlm.nih.gov/31518151
https://pubmed.ncbi.nlm.nih.gov/31518151