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Akademický článek

Gastric Cancer Cell-Derived Exosomal GRP78 Enhances Angiogenesis upon Stimulation of Vascular Endothelial Cells

Autor: Kanako Iha, Akane Sato, Hsin-Yi Tsai, Hikaru Sonoda, Satoshi Watabe, Teruki Yoshimura, Ming-Wei Lin, Etsuro Ito

Publikováno v: Current Issues in Molecular Biology, Vol 44, Iss 12, Pp 6145-6157 (2022)

Exosomes containing glucose-regulated protein 78 (GRP78) are involved in cancer malignancy. GRP78 is thought to promote the tumor microenvironment, leading to angiogenesis. No direct evidence for this role has been reported, however, mainly because o

Externí odkaz: https://doaj.org/article/98e3b1f7c4a046659a0ced34ad884845

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1,2-Disubstituted 1,2-Dihydro-1,2,4,5-tetrazine-3,6-dione as a Dynamic Covalent Bonding Unit at Room Temperature

Autor: Kentaro Kawai, Kazuki Ikeda, Akane Sato, Akira Kabasawa, Masahiro Kojima, Kenta Kokado, Akira Kakugo, Kazuki Sada, Tatsuhiko Yoshino, Shigeki Matsunaga

Publikováno v: Journal of the American Chemical Society. 144:1370-1379

Dynamic covalent bonds are useful tools in a wide range of applications. Although various reversible chemical reactions have been studied for this purpose, the requirement for harsh conditions, such as high temperature and low or high pH, to activate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5919fa8cd0d32beb39da81fb2512c7e3
https://doi.org/10.1021/jacs.1c11665

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Ultrasensitive Detection of GRP78 in Exosomes and Observation of Migration and Proliferation of Cancer Cells by Application of GRP78-Containing Exosomes

Autor: Naoko Tsurusawa, Kanako Iha, Akane Sato, Hsin-Yi Tsai, Hikaru Sonoda, Satoshi Watabe, Teruki Yoshimura, Deng-Chyang Wu, Ming-Wei Lin, Etsuro Ito

Publikováno v: Cancers; Volume 14; Issue 16; Pages: 3887

Cancer cells communicate with each other via exosomes in the tumor microenvironment. However, measuring trace amounts of proteins in exosomes is difficult, and thus the cancer stemness-promoting mechanisms of exosomal proteins have not been elucidate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b18d707b17de8ab18f02ade2ec19ccf5
https://pubmed.ncbi.nlm.nih.gov/36010879

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The vacuolar amino acid transport system is a novel, direct target of GATA transcription factors

Autor: Kana Hondo, Takayuki Sekito, Akane Sato, Miyuki Kawano-Kawada, T. Kimura

Publikováno v: Bioscience, Biotechnology, and Biochemistry. 85:587-599

In Saccharomyces cerevisiae, Avt4 exports neutral and basic amino acids from vacuoles. Previous studies have suggested that the GATA transcription factors, Gln3 and Gat1, which are key regulators that adapt cells in response to changes in amino acid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12de6057c956a12f18b5df19ce0a2364
https://doi.org/10.1093/bbb/zbaa041

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Expression levels of FSHR, IGF1R, CYP11al and HSD3β in cumulus cells can predict in vitro developmental competence of bovine oocytes

Autor: Asuka Hara, Rika Fukumori, Atchalalt Khurchabilig, Yoshikazu Nagao, Shiori Ashibe, Akane Sato

Publikováno v: Zygote. 28:425-431

SummaryThe efficiency of in vitro embryo production technologies would be improved by the development of suitable non-invasive biomarkers that allow the selection of good quality cumulus–oocyte complexes (COCs). The present study used whole, single

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::696eb5fb91ebb862730c58b3752065e0
https://doi.org/10.1017/s0967199420000283

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