Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Akane Morohoshi"'
Autor:
Tadashi Nakagawa, Akane Morohoshi, Yuko Nagasawa, Makiko Nakagawa, Masaki Hosogane, Yasuhiro Noda, Toru Hosoi, Keiko Nakayama
Publikováno v:
Cell Reports, Vol 38, Iss 12, Pp 110541- (2022)
Summary: The histone chaperone complex FACT comprises SPT16 and SSRP1 and contributes to DNA replication, transcription, and repair, but how it plays such various roles is unclear. Here, we show that human SPT16 is ubiquitylated at lysine-674 (K674)
Externí odkaz:
https://doaj.org/article/acc2ec7278fc475baaf6a4baafc163bc
Autor:
Takafumi Matsumura, Taichi Noda, Yuhkoh Satouh, Akane Morohoshi, Shunsuke Yuri, Masaki Ogawa, Yonggang Lu, Ayako Isotani, Masahito Ikawa
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2022)
Fertilization occurs as the culmination of multi-step complex processes. First, mammalian spermatozoa undergo the acrosome reaction to become fusion-competent. Then, the acrosome-reacted spermatozoa penetrate the zona pellucida and adhere to and fina
Externí odkaz:
https://doaj.org/article/b899f6441d4d4b98b3b68916e08a7ac0
Autor:
Akane Morohoshi, Haruhiko Miyata, Keisuke Shimada, Kaori Nozawa, Takafumi Matsumura, Ryuji Yanase, Kogiku Shiba, Kazuo Inaba, Masahito Ikawa
Publikováno v:
PLoS Genetics, Vol 16, Iss 1, p e1008585 (2020)
Flagella and cilia are evolutionarily conserved cellular organelles. Abnormal formation or motility of these organelles in humans causes several syndromic diseases termed ciliopathies. The central component of flagella and cilia is the axoneme that i
Externí odkaz:
https://doaj.org/article/2fadbb674ac84f2b9ff08f74c323ae9b
Autor:
Keisuke Shimada, Soojin Park, Seiya Oura, Taichi Noda, Akane Morohoshi, Martin M. Matzuk, Masahito Ikawa
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Spermatozoa have a streamlined shape to swim through the oviduct to fertilize oocytes. To become svelte spermatozoa, spermatid cytoplasm must be eliminated in several steps including sperm release, which is part of spermiation. Although this process
Autor:
Akane Morohoshi, Haruhiko Miyata, Keizo Tokuhiro, Rie Iida-Norita, Taichi Noda, Yoshitaka Fujihara, Masahito Ikawa
Publikováno v:
Science Advances. 9
Spermatozoa need to undergo an exocytotic event called the acrosome reaction before fusing with eggs. Although calcium ion (Ca 2+ ) is essential for the acrosome reaction, its molecular mechanism remains unknown. Ferlin is a single transmembrane prot
Autor:
Akane Morohoshi, Kaori Nozawa, Thomas X. Garcia, Satoru Takahashi, Hossam H. Shawki, Martin M. Matzuk, Ryan M. Matzuk, Julio M Castaneda, Haruhiko Miyata, Zoulan Xu, Jiang Sun, Yonggang Lu, Masahito Ikawa, Ferheen Abbasi, Zhifeng Yu, Taichi Noda, Darius J Devlin
Publikováno v:
Biology of Reproduction
Developing a safe and effective male contraceptive remains a challenge in the field of medical science. Molecules that selectively target the male reproductive tract and whose targets are indispensable for male reproductive function serve among the b
Autor:
Haruhiko Miyata, Zoulan Xu, Seiya Oura, Keisuke Shimada, Masahito Ikawa, Akane Morohoshi, Takafumi Matsumura, Yuki Oyama
Publikováno v:
The FASEB Journal
Miyata, H., Shimada, K., Morohoshi, A., Oura, S., Matsumura, T., Xu, Z., . . . Ikawa, M. (2020). Testis-enriched kinesin KIF9 is important for progressive motility in mouse spermatozoa. FASEB Journal, 34(4), 5389-5400. doi:10.1096/fj.201902755R
Publikováno v:
Experimental Animals
Infertility is a global health issue that affects 1 in 6 couples, with male factors contributing to 50% of cases. The flagellar axoneme is a motility apparatus of spermatozoa, and disruption of its structure or function could lead to male infertility
Publikováno v:
Development (Cambridge, England)
article-version (VoR) Version of Record
article-version (VoR) Version of Record
The acrosome is a cap-shaped, Golgi-derived membranous organelle that is located over the anterior of the sperm nucleus and highly conserved throughout evolution. Although morphological changes during acrosome biogenesis in spermatogenesis have been
Autor:
Tadashi Nakagawa, Akane Morohoshi, Yuko Nagasawa, Makiko Nakagawa, Masaki Hosogane, Yasuhiro Noda, Toru Hosoi, Keiko Nakayama
Publikováno v:
Cell reports. 38(12)
The histone chaperone complex FACT comprises SPT16 and SSRP1 and contributes to DNA replication, transcription, and repair, but how it plays such various roles is unclear. Here, we show that human SPT16 is ubiquitylated at lysine-674 (K674) by the DC