Magnetic Nanoparticle-Based Dianthin Targeting for Controlled Drug Release Using the Endosomal Escape Enhancer SO1861

Autor: Ajmal Zarinwall, Mazdak Asadian-Birjand, Didem Ag Seleci, Viktor Maurer, Alexandra Trautner, Georg Garnweitner, Hendrik Fuchs

Publikováno v: Nanomaterials, Vol 11, Iss 4, p 1057 (2021)

Targeted tumor therapy can provide the basis for the inhibition of tumor growth. However, a number of toxin-based therapeutics lack efficacy because of insufficient endosomal escape after being internalized by endocytosis. To address this problem, th

Externí odkaz: https://doaj.org/article/2a886b88f0554675919fa7eb95619329

All-in-one superparamagnetic and SERS-active niosomes for dual-targeted in vitro detection of breast cancer cells

Autor: Viktor Maurer, Ajmal Zarinwall, Zunhao Wang, Stefan Wundrack, Nicole Wundrack, Didem Ag Seleci, Vivien Helm, Daniil Otenko, Claudia Frank, Fred Schaper, Rainer Stosch, Georg Garnweitner

Publikováno v: Sensors & Diagnostics. 1:469-484

Encapsulation of iron oxide and gold nanoparticles into the bilayer structure of transferrin-modified niosomes enables greatly enhanced and contamination-free SERS-signals in vitro as well as a dual-targeting functionality towards cancer cells.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7ac3ab42c5c45462ea2b1d8c8846b16e
https://doi.org/10.1039/d2sd00020b

Comprehensive Characterization of APTES Surface Modifications of Hydrous Boehmite Nanoparticles

Autor: Heinz Sturm, Ulrike Braun, Tassilo Waniek, Reza Saadat, Ajmal Zarinwall, Georg Garnweitner

Publikováno v: Langmuir. 37:171-179

Hydrous boehmite (γ-AlOOH) nanoparticles (BNP) show great potential as nanoscale filler for the fabrication of fiber reinforced nanocomposite materials. Notably, the particle-matrix interaction has been demonstrated to be decisive for improving the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a69f7b5f886a9734b9e3dadebf9172b1
https://doi.org/10.1021/acs.langmuir.0c02682

In-Vitro Application of Magnetic Hybrid Niosomes: Targeted siRNA-Delivery for Enhanced Breast Cancer Therapy

Autor: Ajmal Zarinwall, Thomas Scheper, Vesna Bucan, Viktor Maurer, Selin Altin, Peter M. Vogt, Georg Garnweitner, Bilal Temel, Sarah Strauß, Didem Ag Seleci, Frank Stahl

Publikováno v: Pharmaceutics, Vol 13, Iss 394, p 394 (2021)
Pharmaceutics
Volume 13
Issue 3
Pharmaceutics 2021, 13(3), 394; https://doi.org/10.3390/pharmaceutics13030394--Pharmaceutics--http://www.bibliothek.uni-regensburg.de/ezeit/?2527217--http://www.mdpi.com/journal/pharmaceutics--https://www.ncbi.nlm.nih.gov/pmc/journals/2103/--1999-4923--1999-4923

Even though the administration of chemotherapeutic agents such as erlotinib is clinically established for the treatment of breast cancer, its efficiency and the therapy outcome can be greatly improved using RNA interference (RNAi) mechanisms for a co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec477da298b9b4e335ca2a18d2f24176
https://www.mdpi.com/1999-4923/13/3/394

Downstream processing of hyperforin from Hypericum perforatum root cultures

Autor: Ajmal Zarinwall, Ludger Beerhues, Mariam Gaid, Stephan Scholl, Paul Haas

Publikováno v: European Journal of Pharmaceutics and Biopharmaceutics. 126:104-107

Hyperforin is a major metabolite of the medicinal plant Hypericum perforatum (St. John's Wort) and has recently been found in hormone induced root cultures. The objective of this study is to identify a downstream process for the production of a hyper

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ed98cc2f4fedfb5cefd99ddeb19c4cd
https://doi.org/10.1016/j.ejpb.2017.06.026