Výsledky vyhledávání - "Ajjampura C. Vinayaka"

Akademický článek

Cannabis compounds exhibit anti-inflammatory activity in vitro in COVID-19-related inflammation in lung epithelial cells and pro-inflammatory activity in macrophages

Autor: Seegehalli M. Anil, Nurit Shalev, Ajjampura C. Vinayaka, Stalin Nadarajan, Dvora Namdar, Eduard Belausov, Irit Shoval, Karthik Ananth Mani, Guy Mechrez, Hinanit Koltai

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)

Abstract Cannabis sativa is widely used for medical purposes and has anti-inflammatory activity. This study intended to examine the anti-inflammatory activity of cannabis on immune response markers associated with coronavirus disease 2019 (COVID-19)

Externí odkaz: https://doaj.org/article/6e200a9098694dec83257e5ff1fb6b1c

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Akademický článek

Phytocannabinoids Act Synergistically with Non-Steroidal Anti-Inflammatory Drugs Reducing Inflammation in 2D and 3D In Vitro Models

Autor: Ajjampura C. Vinayaka, Nurit Shalev, Seegehalli M. Anil, Sudeep Tiwari, Navin Kumar, Eduard Belausov, Karthik Ananth Mani, Guy Mechrez, Hinanit Koltai

Publikováno v: Pharmaceuticals, Vol 15, Iss 12, p 1559 (2022)

Lung inflammation is associated with elevated pro-inflammatory cytokines and chemokines. Treatment with FCBD:std (standard mix of cannabidiol [CBD], cannabigerol [CBG] and tetrahydrocannabivarin [THCV]) leads to a marked reduction in the inflammation

Externí odkaz: https://doaj.org/article/8dd6fd39a3d74aa2bdf549fd7573d496

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Akademický článek

Phytocannabinoid Compositions from Cannabis Act Synergistically with PARP1 Inhibitor against Ovarian Cancer Cells In Vitro and Affect the Wnt Signaling Pathway

Autor: Nurit Shalev, Michelle Kendall, Seegehalli M. Anil, Sudeep Tiwari, Hadar Peeri, Navin Kumar, Eduard Belausov, Ajjampura C. Vinayaka, Hinanit Koltai

Publikováno v: Molecules, Vol 27, Iss 21, p 7523 (2022)

Ovarian cancer (OC) is the single most lethal gynecologic malignancy. Cannabis sativa is used to treat various medical conditions, and is cytotoxic to a variety of cancer types. We sought to examine the effectiveness of different combinations of cann

Externí odkaz: https://doaj.org/article/f2b692693a0b4343a97575762cc37b10

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Akademický článek

Cannabis-Derived Compounds Cannabichromene and Δ9-Tetrahydrocannabinol Interact and Exhibit Cytotoxic Activity against Urothelial Cell Carcinoma Correlated with Inhibition of Cell Migration and Cytoskeleton Organization

Autor: Omer Anis, Ajjampura C. Vinayaka, Nurit Shalev, Dvora Namdar, Stalin Nadarajan, Seegehalli M. Anil, Ofer Cohen, Eduard Belausov, Jacob Ramon, Einav Mayzlish Gati, Hinanit Koltai

Publikováno v: Molecules, Vol 26, Iss 2, p 465 (2021)

Cannabis sativa contains more than 500 constituents, yet the anticancer properties of the vast majority of cannabis compounds remains unknown. We aimed to identify cannabis compounds and their combinations presenting cytotoxicity against bladder urot

Externí odkaz: https://doaj.org/article/aece58dbabc24de3942d6e917d8bc1d5

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Cannabis compounds exhibit anti-inflammatory activity in vitro in COVID-19-related inflammation in lung epithelial cells and pro-inflammatory activity in macrophages

Autor: Ajjampura C. Vinayaka, Seegehalli M Anil, Karthik Ananth Mani, Hinanit Koltai, Guy Mechrez, Irit Shoval, Nurit Shalev, Stalin Nadarajan, Eduard Belausov, Dvora Namdar

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports

Cannabis sativa is widely used for medical purposes and has anti-inflammatory activity. This study intended to examine the anti-inflammatory activity of cannabis on immune response markers associated with coronavirus disease 2019 (COVID-19) inflammat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5463956c42026d7417eacd1891073be9
https://doaj.org/article/6e200a9098694dec83257e5ff1fb6b1c

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Synergistic cytotoxic activity of cannabinoids fromcannabis sativaagainst cutaneous T-cell lymphoma (CTCL)in-vitroandex-vivo

Autor: Amir Tiroler, Dvora Namdar, Guy Drori, Hinanit Koltai, Lilach Moyal, Stalin Nadarajan, Emmilia Hodak, Iris Amitay-Laish, Adi Faigenboim, Moran Mazuz, Owen Van Cauwenberghe, Avi Drori, Ajjampura C. Vinayaka, Ido Lubin, Batia Gorovitz-Haris

Publikováno v: Oncotarget. 11:1141-1156

Cannabis sativa produces hundreds of phytocannabinoids and terpenes. Mycosis fungoides (MF) is the most common type of cutaneous T-cell lymphoma (CTCL), characterized by patches, plaques and tumors. Sezary is a leukemic stage of CTCL presenting with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9483e89a34a19dfd71d76402f4c9e7bc
https://doi.org/10.18632/oncotarget.27528

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Δ9–Tetrahydrocannabinol (THC)-Rich Compositions from Cannabis Have Cytotoxic Activity Against Ovarian Cancer Cells and Act Synergistically With Niraparib in vitro

Autor: Michelle Kendall, Nurit Shalev, Seegehalli M Anil, Hinanit Koltai, Ajjampura C. Vinayaka

Ovarian cancer (OC) is the most lethal gynecologic malignancy. Cannabis sativa is being used to treat different medical conditions. We sought to examine the effectiveness of combinations of cannabis compounds against OC. Cytotoxic activity was determ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b299a685d5d77a60ef6540f386e7418f

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Akademický článek

A new ibuprofen derivative inhibits platelet aggregation and ROS mediated platelet apoptosis.

Autor: Kodagahalli S Rakesh, Swamy Jagadish, Ajjampura C Vinayaka, Mahadevappa Hemshekhar, Manoj Paul, Ram M Thushara, Mahalingam S Sundaram, Toreshettahally R Swaroop, Chakrabhavi D Mohan, Basappa, Marilinganadoddi P Sadashiva, Kempaiah Kemparaju, Kesturu S Girish, Kanchugarakoppal S Rangappa

Publikováno v: PLoS ONE, Vol 9, Iss 9, p e107182 (2014)

Thrombocytopenia is a serious issue connected with the pathogenesis of several human diseases including chronic inflammation, arthritis, Alzheimer's disease, cardiovascular diseases (CVDs) and other oxidative stress-associated pathologies. The indisc

Externí odkaz: https://doaj.org/article/71b42da3762949dbae4ffd9fd325e5f1

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Autor: Eduard Belausov, Dvora Namdar, Ofer Cohen, Jacob Ramon, Ajjampura C. Vinayaka, Hinanit Koltai, Einav Mayzlish Gati, Omer Anis, Seegehalli M Anil, Stalin Nadarajan, Nurit Shalev

Publikováno v: Molecules, Vol 26, Iss 465, p 465 (2021)
Molecules
Volume 26
Issue 2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4acedc2134539afcae77e46a0b2a570
https://www.mdpi.com/1420-3049/26/2/465

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Cannabis compounds have anti-inflammatory activity in lung epithelial cells but pro-inflammatory activity in macrophages while increasing phagocytosis in vitro

Autor: Seegehalli M Anil, Nurit Shalev, Ajjampura C Vinayaka, Stalin Nadarajan, Dvory Namdar, Eduard Belausov, Irit Shoval, Karthik Ananth Mani, Guy Mechrez, Hinanit Koltai

Cannabis sativa is widely used for medical purposes and has anti-inflammatory activity. The purpose of this study was to examine the anti-inflammatory activity of cannabis on markers of immune responses associated with Coronavirus disease 2019 (COVID

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::70381c44ba457763c36dfdab6d4d5533
https://doi.org/10.21203/rs.3.rs-89166/v1

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