Zobrazeno 1 - 10
of 263
pro vyhledávání: '"Ajjai Alva"'
Autor:
Yousef Zakharia, Eric A. Singer, Satwik Acharyya, Rohan Garje, Monika Joshi, David Peace, Veera Baladandayuthapani, Annesha Majumdar, Xiong Li, Claudia Lalancette, Ilona Kryczek, Weiping Zou, Ajjai Alva
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Epigenetic modulation is well established in hematologic malignancies but to a lesser degree in solid tumors. Here we report the results of a phase Ib/II study of guadecitabine and durvalumab in advanced clear cell renal cell carcinoma (ccRC
Externí odkaz:
https://doaj.org/article/b61aeb1f55d4407694b815cd85d405bf
Autor:
Di Sun, Lubomir Hadjiiski, John Gormley, Heang-Ping Chan, Elaine M. Caoili, Richard H. Cohan, Ajjai Alva, Vikas Gulani, Chuan Zhou
Publikováno v:
Cancers, Vol 15, Iss 17, p 4372 (2023)
Accurate survival prediction for bladder cancer patients who have undergone radical cystectomy can improve their treatment management. However, the existing predictive models do not take advantage of both clinical and radiological imaging data. This
Externí odkaz:
https://doaj.org/article/de80d1d9dbee4af69f9ae7d8e7a4b337
Autor:
Di Sun, Lubomir Hadjiiski, Ajjai Alva, Yousef Zakharia, Monika Joshi, Heang-Ping Chan, Rohan Garje, Lauren Pomerantz, Dean Elhag, Richard H. Cohan, Elaine M. Caoili, Wesley T. Kerr, Kenny H. Cha, Galina Kirova-Nedyalkova, Matthew S. Davenport, Prasad R. Shankar, Isaac R. Francis, Kimberly Shampain, Nathaniel Meyer, Daniel Barkmeier, Sean Woolen, Phillip L. Palmbos, Alon Z. Weizer, Ravi K. Samala, Chuan Zhou, Martha Matuszak
Publikováno v:
Tomography, Vol 8, Iss 2, Pp 644-656 (2022)
This observer study investigates the effect of computerized artificial intelligence (AI)-based decision support system (CDSS-T) on physicians’ diagnostic accuracy in assessing bladder cancer treatment response. The performance of 17 observers was e
Externí odkaz:
https://doaj.org/article/285bf5fa61c2417fa02ec49cebcbaaf8
Autor:
Dominick Bossé, Wanling Xie, Xun Lin, Ronit Simantov, Aly-Khan A. Lalani, Jeffrey Graham, J. Connor Wells, Frede Donskov, Brian Rini, Benoit Beuselinck, Ajjai Alva, Aaron Hansen, Lori Wood, Denis Soulières, Christian Kollmannsberger, Francois Patenaude, Daniel Y.C. Heng, Toni K. Choueiri, Rana R. McKay
Publikováno v:
JCO Global Oncology, Vol , Iss 6, Pp 293-306 (2020)
PURPOSETo investigate whether black race is an independent predictor of overall survival (OS) in metastatic renal cell carcinoma (mRCC).METHODSWe performed a retrospective 2-cohort (International Metastatic Renal Cell Carcinoma Database Consortium [I
Externí odkaz:
https://doaj.org/article/7f8755e52c91411ab1c49335f24de728
Autor:
Ajjai Alva, Vincent Ma, Leslie Fecher, Kent Griffith, Jessica Waninger, Stephanie Daignault-Newton, Christopher Lao
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/67bd338de87043dd95ede939173065a3
Autor:
Zachery R. Reichert, Tadas Kasputis, Srinivas Nallandhighal, Sophia M. Abusamra, Amy Kasputis, Saloni Haruray, Yugang Wang, Shamara Williams, Udit Singhal, Ajjai Alva, Frank C. Cackowski, Megan E. V. Caram, Phillip L. Palmbos, Sarah E. Yentz, David C. Smith, Joshi J. Alumkal, Todd M. Morgan
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1, p 4 (2021)
The substantial biological heterogeneity of metastatic prostate cancer has hindered the development of personalized therapeutic approaches. Therefore, it is difficult to predict the course of metastatic hormone-sensitive prostate cancer (mHSPC), with
Externí odkaz:
https://doaj.org/article/9735b663c5a84a45bcdc130635d0545f
Autor:
Laura S Graham, Bruce Montgomery, Heather H Cheng, Evan Y Yu, Peter S Nelson, Colin Pritchard, Stephanie Erickson, Ajjai Alva, Michael T Schweizer
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0233260 (2020)
BACKGROUND:While response rates to anti-PD1 therapy are low in unselected metastatic castration resistant prostate cancer (mCRPC) patients, those with inactivating mutations in mismatch repair (MMR) genes (i.e. MMR deficiency; MMRd) or microsatellite
Externí odkaz:
https://doaj.org/article/72aa76cc3eb9475eb65eaa44e2277623
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-5 (2018)
Abstract Background Immune check point inhibitors (ICIs) have emerged as a new therapeutic paradigm for a variety of malignancies including metastatic melanoma. As the use of ICIs expand, immune-mediated adverse events are becoming a common occurrenc
Externí odkaz:
https://doaj.org/article/1e1f73ceee7245ffbd2c90d76bde1821
Autor:
Kenny H. Cha, Lubomir Hadjiiski, Heang-Ping Chan, Alon Z. Weizer, Ajjai Alva, Richard H. Cohan, Elaine M. Caoili, Chintana Paramagul, Ravi K. Samala
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Cross-sectional X-ray imaging has become the standard for staging most solid organ malignancies. However, for some malignancies such as urinary bladder cancer, the ability to accurately assess local extent of the disease and understand respo
Externí odkaz:
https://doaj.org/article/fa5b71fe40344297b76499a04ea5ed9b
Publikováno v:
Urology Case Reports, Vol 3, Iss 4, Pp 98-100 (2015)
Bladder cancer rarely presents clinically with a myelophthisic picture from diffuse bone marrow infiltration especially in the absence of detectable skeletal metastases. A 75-year old man presented with newly diagnosed urothelial cell carcinoma of th
Externí odkaz:
https://doaj.org/article/ee693961f85c4c79907216fbf3e4e429