Zobrazeno 1 - 10
of 262
pro vyhledávání: '"Ajjai, Alva"'
Autor:
Yousef Zakharia, Eric A. Singer, Satwik Acharyya, Rohan Garje, Monika Joshi, David Peace, Veera Baladandayuthapani, Annesha Majumdar, Xiong Li, Claudia Lalancette, Ilona Kryczek, Weiping Zou, Ajjai Alva
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Epigenetic modulation is well established in hematologic malignancies but to a lesser degree in solid tumors. Here we report the results of a phase Ib/II study of guadecitabine and durvalumab in advanced clear cell renal cell carcinoma (ccRC
Externí odkaz:
https://doaj.org/article/b61aeb1f55d4407694b815cd85d405bf
Autor:
Di Sun, Lubomir Hadjiiski, Ajjai Alva, Yousef Zakharia, Monika Joshi, Heang-Ping Chan, Rohan Garje, Lauren Pomerantz, Dean Elhag, Richard H. Cohan, Elaine M. Caoili, Wesley T. Kerr, Kenny H. Cha, Galina Kirova-Nedyalkova, Matthew S. Davenport, Prasad R. Shankar, Isaac R. Francis, Kimberly Shampain, Nathaniel Meyer, Daniel Barkmeier, Sean Woolen, Phillip L. Palmbos, Alon Z. Weizer, Ravi K. Samala, Chuan Zhou, Martha Matuszak
Publikováno v:
Tomography, Vol 8, Iss 2, Pp 644-656 (2022)
This observer study investigates the effect of computerized artificial intelligence (AI)-based decision support system (CDSS-T) on physicians’ diagnostic accuracy in assessing bladder cancer treatment response. The performance of 17 observers was e
Externí odkaz:
https://doaj.org/article/285bf5fa61c2417fa02ec49cebcbaaf8
Autor:
Dominick Bossé, Wanling Xie, Xun Lin, Ronit Simantov, Aly-Khan A. Lalani, Jeffrey Graham, J. Connor Wells, Frede Donskov, Brian Rini, Benoit Beuselinck, Ajjai Alva, Aaron Hansen, Lori Wood, Denis Soulières, Christian Kollmannsberger, Francois Patenaude, Daniel Y.C. Heng, Toni K. Choueiri, Rana R. McKay
Publikováno v:
JCO Global Oncology, Vol , Iss 6, Pp 293-306 (2020)
PURPOSETo investigate whether black race is an independent predictor of overall survival (OS) in metastatic renal cell carcinoma (mRCC).METHODSWe performed a retrospective 2-cohort (International Metastatic Renal Cell Carcinoma Database Consortium [I
Externí odkaz:
https://doaj.org/article/7f8755e52c91411ab1c49335f24de728
Autor:
Ziad Bakouny, Talal El Zarif, Shaan Dudani, J. Connor Wells, Chun Loo Gan, Frede Donskov, Julia Shapiro, Ian D. Davis, Francis Parnis, Praful Ravi, John A. Steinharter, Neeraj Agarwal, Ajjai Alva, Lori Wood, Anil Kapoor, Jose M. Ruiz Morales, Christian Kollmannsberger, Benoit Beuselinck, Wanling Xie, Daniel Y.C. Heng, Toni K. Choueiri
Publikováno v:
European Urology. 83:145-151
The role of upfront cytoreductive nephrectomy (CN) for metastatic renal cell carcinoma (mRCC) in the era of immune checkpoint inhibitors is unclear.To evaluate the relationship between upfront CN and clinical outcomes in the setting of mRCC treated w
Autor:
Ajjai Alva, Vincent Ma, Leslie Fecher, Kent Griffith, Jessica Waninger, Stephanie Daignault-Newton, Christopher Lao
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/67bd338de87043dd95ede939173065a3
Autor:
Laura S Graham, Bruce Montgomery, Heather H Cheng, Evan Y Yu, Peter S Nelson, Colin Pritchard, Stephanie Erickson, Ajjai Alva, Michael T Schweizer
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0233260 (2020)
BACKGROUND:While response rates to anti-PD1 therapy are low in unselected metastatic castration resistant prostate cancer (mCRPC) patients, those with inactivating mutations in mismatch repair (MMR) genes (i.e. MMR deficiency; MMRd) or microsatellite
Externí odkaz:
https://doaj.org/article/72aa76cc3eb9475eb65eaa44e2277623
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-5 (2018)
Abstract Background Immune check point inhibitors (ICIs) have emerged as a new therapeutic paradigm for a variety of malignancies including metastatic melanoma. As the use of ICIs expand, immune-mediated adverse events are becoming a common occurrenc
Externí odkaz:
https://doaj.org/article/1e1f73ceee7245ffbd2c90d76bde1821
Autor:
Zachery R. Reichert, Tadas Kasputis, Srinivas Nallandhighal, Sophia M. Abusamra, Amy Kasputis, Saloni Haruray, Yugang Wang, Shamara Williams, Udit Singhal, Ajjai Alva, Frank C. Cackowski, Megan E. V. Caram, Phillip L. Palmbos, Sarah E. Yentz, David C. Smith, Joshi J. Alumkal, Todd M. Morgan
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1, p 4 (2021)
The substantial biological heterogeneity of metastatic prostate cancer has hindered the development of personalized therapeutic approaches. Therefore, it is difficult to predict the course of metastatic hormone-sensitive prostate cancer (mHSPC), with
Externí odkaz:
https://doaj.org/article/9735b663c5a84a45bcdc130635d0545f
Autor:
Dimitrios Makrakis, Rafee Talukder, Genevieve Ihsiu Lin, Leonidas N. Diamantopoulos, Scott Dawsey, Shilpa Gupta, Lucia Carril-Ajuria, Daniel Castellano, Ivan de Kouchkovsky, Vadim S. Koshkin, Joseph J. Park, Ajjai Alva, Mehmet A. Bilen, Tyler F. Stewart, Rana R. McKay, Nishita Tripathi, Neeraj Agarwal, Naomi Vather-Wu, Yousef Zakharia, Rafael Morales-Barrera, Michael E. Devitt, Alessio Cortellini, Claudia Angela Maria Fulgenzi, David J. Pinato, Ariel Nelson, Christopher J. Hoimes, Kavita Gupta, Benjamin A. Gartrell, Alex Sankin, Abhishek Tripathi, Roubini Zakopoulou, Aristotelis Bamias, Jure Murgic, Ana Fröbe, Alejo Rodriguez-Vida, Alexandra Drakaki, Sandy Liu, Eric Lu, Vivek Kumar, Giuseppe Di Lorenzo, Monika Joshi, Pedro Isaacsson-Velho, Lucia Alonso Buznego, Ignacio Duran, Marcus Moses, Albert Jang, Pedro Barata, Guru Sonpavde, Evan Y. Yu, Robert Bruce Montgomery, Petros Grivas, Ali Raza Khaki
Publikováno v:
Clin Genitourin Cancer
Clinical genitourinary cancer, vol 20, iss 5
Clinical genitourinary cancer, vol 20, iss 5
Immune checkpoint inhibitors are a well-established treatment option for advanced urothelial carcinoma, and biomarkers of response are needed for better patient selection. We show that metastatic disease confined to lymph nodes is associated with bet
Autor:
Kenny H. Cha, Lubomir Hadjiiski, Heang-Ping Chan, Alon Z. Weizer, Ajjai Alva, Richard H. Cohan, Elaine M. Caoili, Chintana Paramagul, Ravi K. Samala
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Cross-sectional X-ray imaging has become the standard for staging most solid organ malignancies. However, for some malignancies such as urinary bladder cancer, the ability to accurately assess local extent of the disease and understand respo
Externí odkaz:
https://doaj.org/article/fa5b71fe40344297b76499a04ea5ed9b