Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Ajinath Kale"'
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Antiviral drugs such as Remdesivir (Veklury), Nirmatrelvir with Ritonavir (Paxlovid), Azvudine, and Molnupiravir (Lagevrio) can reduce the risk for severe and fatal Coronavirus Disease (COVID)-19. Although chronic kidney disease is a highly prevalent
Externí odkaz:
https://doaj.org/article/263ec1b938684aa58e5770dfa5228be5
Publikováno v:
Cells, Vol 12, Iss 20, p 2440 (2023)
Calcineurin inhibitors (CNI) can suppress allo- and autoimmunity by suppressing T cell function but also have anti-proteinuric effects by stabilizing the cellular components of the kidney’s filtration barrier. Therefore, CNI are used in autoimmune
Externí odkaz:
https://doaj.org/article/3217f31635ca41c3ab86ba80592dae7d
Publikováno v:
Archives of Physiology and Biochemistry. :1-9
Persistent hyperglycaemia increases SET7/9 expression and endoplasmic reticulum (ER) stress which causes inflammation, apoptosis, and fibrosis in renal tubular epithelial cells leading to diabetic kidney disease (DKD).Current study explores the renop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52ac8c7b73671ff59e65fe886242656f
https://doi.org/10.1080/13813455.2022.2105365
https://doi.org/10.1080/13813455.2022.2105365
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 100:234-239
Persistent hyperglycemia in type 1 diabetes triggers numerous signaling pathways, which may prove deleterious to the endothelium. As hyperglycemia damages the endothelial layer via multiple signaling pathways, including enhanced oxidative stress, dow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d46dd4e52a989ded6077c5ec7af7295
https://doi.org/10.1139/cjpp-2021-0170
https://doi.org/10.1139/cjpp-2021-0170
Publikováno v:
BioDrugs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67cefa77acb97e8246f025312f395efb
https://doi.org/10.1007/s40259-023-00597-3
https://doi.org/10.1007/s40259-023-00597-3
Publikováno v:
Nephrology Dialysis Transplantation. 38:819-825
Klotho is a transmembrane anti-ageing protein that exists in three forms, i.e. α-Klotho, β-Klotho and γ-Klotho, with distinct organ-specific expression and functions in the body. Here we focus on α-Klotho (hereafter Klotho), abundantly expressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6669c34739e153e03842789e176f0e5
https://doi.org/10.1093/ndt/gfab340
https://doi.org/10.1093/ndt/gfab340
Publikováno v:
Food & Function.
Toll-like receptor 4 (TLR4) and sodium-glucose co-transporter 2 (SGLT2) signaling is involved in the pathogenesis of diabetes-associated kidney diseases.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::194f0794cb3cf90428bc089b8063cc80
https://doi.org/10.1039/d3fo01379k
https://doi.org/10.1039/d3fo01379k
Publikováno v:
Journal of cellular physiologyREFERENCES.
Acute kidney injury (AKI) and chronic kidney disease (CKD) are global health concerns with increasing rates in morbidity and mortality. Transition from AKI-to-CKD is common and requires awareness in the management of AKI survivors. AKI-to-CKD transit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdb8ef191f8b847c435b56e0680f375d
https://pubmed.ncbi.nlm.nih.gov/36409755
https://pubmed.ncbi.nlm.nih.gov/36409755
Publikováno v:
Mitochondrion. 66
Acute kidney injury (AKI) is a global health concern associated with high morbidity and mortality. AKI etiology is linked to mitochondrial dysfunction along with oxidative stress and inflammation. The defective mitochondria are removed via mitophagy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2a4953b96ed6640b0cbb816b8ae838e
https://pubmed.ncbi.nlm.nih.gov/35985440
https://pubmed.ncbi.nlm.nih.gov/35985440
Publikováno v:
Molecular and cellular biochemistry.
Kidney disease is the 6th fastest-growing cause of death and a serious global health concern that urges effective therapeutic options. The inflammatory response is an initial reaction from immune and parenchymal cells in kidney diseases. Toll-like re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75f2c3710718b980d9c1aab9fc0cdcd9
https://pubmed.ncbi.nlm.nih.gov/36586092
https://pubmed.ncbi.nlm.nih.gov/36586092