Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ajey, Jain"'
Autor:
Praveen Ballabh, Alfred N. Krauss, Jaishree Kumari, Junghee J Shin, Martin Lesser, Ajey Jain, Susanna Cunningham-Rundles, Peter A. M. Auld
Publikováno v:
Pediatrics. 111:461-468
Objective. To evaluate longitudinal change in arterial blood plasma levels of soluble adhesion molecules in infants of Methods. We measured plasma concentrations of soluble L-selectin (sL-selectin), soluble E-selectin (sE-selectin), and soluble inter
Autor:
Ajey Jain, Jaishree Kumari, Susanna Cunningham-Rundles, Alfred N. Krauss, Peter A. M. Auld, Praveen Ballabh, Maciej Simm
Publikováno v:
American Journal of Perinatology. 20:465-476
A key role for inflammation in the etiology of bronchopulmonary dysplasia (BPD) has been proposed. In the present study we have evaluated lymphocyte subpopulations in 39 premature infants with respiratory distress syndrome (RDS) who did or did not de
Autor:
Quihu Shi, Alfred N. Krauss, Martin Lesser, Zubair H. Aghai, Peter A. M. Auld, Hartmut M Hanauske-Abel, Lorna Lumicao, Ajey Jain, Ronald Arevalo
Publikováno v:
Neonatology. 81:16-22
Basement membranes, critical for vital organs like the lungs, consist of two interwoven homopolymers, one assembled by type IV collagens and one by laminins. We hypothesized their serum antigens C-IV and P1, respectively, to be global measures for th
Autor:
Rakesh K. Singhal, Ajey Jain
Publikováno v:
Neonatology. 77:261-266
Human premature neonates suffer from respiratory distress syndrome due to immature lungs and require assisted ventilation with high concentrations of oxygen. Hyperoxic exposure and/or antioxidant deficiency causes an increase in the lung levels of re
Autor:
Ajey Jain, Alton Meister, William W. Frayer, Peter A. M. Auld, Einar Stole, Johannes Martensson
Publikováno v:
Proceedings of the National Academy of Sciences. 88:9360-9364
A model for oxidative stress is described in which glutathione (GSH) synthesis is selectively blocked in newborn rats by administration of L-buthionine-(S,R)-sulfoximine (BSO). In this model, the normal endogenous physiological formation of reactive
Autor:
Praveen Ballabh, Claudia Califano, Maciej Simm, Jaishree Kumari, Alfred N. Krauss, Martin Lesser, Susanna Cunningham-Rundles, Ajey Jain
Publikováno v:
Archives of disease in childhood. Fetal and neonatal edition. 89(1)
Aims: To study a longitudinal change in the expression of adhesion molecules CD11b, CD18, and CD62L on neutrophils and monocytes in very low birth weight babies who develop respiratory distress syndrome, to compare these levels between bronchopulmona
Autor:
Zubair H, Aghai, Ronald, Arevalo, Lorna, Lumicao, Martin, Lesser, Quihu, Shi, Ajey, Jain, Alfred N, Krauss, Peter A M, Auld, Hartmut M, Hanauske-Abel
Publikováno v:
Biology of the neonate. 81(1)
Basement membranes, critical for vital organs like the lungs, consist of two interwoven homopolymers, one assembled by type IV collagens and one by laminins. We hypothesized their serum antigens C-IV and P1, respectively, to be global measures for th
Autor:
Peter A. M. Auld, Robert F. Ward, Johannes Martensson, Jose Rodrigues, Ajey Jain, Morton K. Schwartz, Taral Mehta
Publikováno v:
Pediatric pulmonology. 20(3)
Respiratory distress in premature newborns is associated with deficiency of surfactant in the bronchoalveolar lining fluid; this may be influenced by a local deficiency of antioxidants. Severe L-buthionine-S,R-sulfoximine-induced depletion of glutath
Autor:
Nancy G. Kennaway, Johannes Martensson, Peter A. M. Auld, Ajey Jain, Neil R. M. Buist, Berkley R. Powell
Publikováno v:
The Journal of pediatrics. 124(2)
A 45-month-old girl with 5-oxoprolinuria (pyroglutamic aciduria), hemolysis, and marked glutathione depletion caused by deficiency of glutathione synthetase was followed before and during treatment with ascorbate or N-acetylcysteine. High doses of as
Autor:
Johannes Martensson, Ajey Jain, Alton Meister, Peter A. M. Auld, Alfred N. Krauss, Taral Mehta
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 89(11)
Glutathione deficiency in adult mice leads to lung type 2 cell lamellar body and mitochondrial damage; as reported here, these effects are associated with marked decrease of the levels of phosphatidylcholine (the main component of lung surfactant) in