Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Ajerico del-Rosario"'
Autor:
Alexandra Nikonova, Musa Khaitov, David J. Jackson, Stephanie Traub, Maria-Belen Trujillo-Torralbo, Dmitriy A. Kudlay, Anton S. Dvornikov, Ajerico del-Rosario, Rudolf Valenta, Luminita A. Stanciu, Rahim Khaitov, Sebastian L. Johnston
Publikováno v:
EBioMedicine, Vol 54, Iss , Pp - (2020)
Background: Macrophages (Mф) can be M1/M2 polarized by Th1/2 signals, respectively. M2-like Mф are thought to be important in asthma pathogenesis, and M1-like in anti-infective immunity, however their roles in virus-induced asthma exacerbations are
Externí odkaz:
https://doaj.org/article/83599ee0d791431fa8664baecb15c64e
Autor:
Trevor T. Hansel, Tanushree Tunstall, Maria-Belen Trujillo-Torralbo, Betty Shamji, Ajerico del-Rosario, Jaideep Dhariwal, Paul D.W. Kirk, Michael P.H. Stumpf, Jens Koopmann, Aurica Telcian, Julia Aniscenko, Leila Gogsadze, Eteri Bakhsoliani, Luminita Stanciu, Nathan Bartlett, Michael Edwards, Ross Walton, Patrick Mallia, Toby M. Hunt, Trevor L. Hunt, Duncan G. Hunt, John Westwick, Matthew Edwards, Onn Min Kon, David J. Jackson, Sebastian L. Johnston
Publikováno v:
EBioMedicine, Vol 19, Iss C, Pp 128-138 (2017)
Background: Rhinovirus infection is a major cause of asthma exacerbations. Objectives: We studied nasal and bronchial mucosal inflammatory responses during experimental rhinovirus-induced asthma exacerbations. Methods: We used nasosorption on days 0,
Externí odkaz:
https://doaj.org/article/ab25bde444214ba699561d21d6a05e09
Type I conventional dendritic cells relate to disease severity in virus-induced asthma exacerbations
Autor:
Aoife, Cameron, Jaideep, Dhariwal, Nadine, Upton, Ismael, Ranz Jimenez, Malte, Paulsen, Ernie, Wong, Maria-Belen, Trujillo-Torralbo, Ajerico, Del Rosario, David J, Jackson, Michael R, Edwards, Sebastian L, Johnston, Ross P, Walton
Publikováno v:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 52(4)
Rhinoviruses are the major precipitant of asthma exacerbations and individuals with asthma experience more severe/prolonged rhinovirus infections. Concurrent viral infection and allergen exposure synergistically increase exacerbation risk. Although d
Autor:
David J. Cousins, Ernie Wong, Trevor T. Hansel, David A. Jackson, Ajerico del Rosario, Eteri Bakhsoliani, Jaideep Dhariwal, Malte Paulsen, Michael R. Edwards, Aoife Cameron, Ross P. Walton, Belen Trujillo-Torralbo, Sebastian L. Johnston
Rationale Type 2 innate lymphoid cells (ILC2s) are significant sources of type 2 cytokines, which are implicated in the pathogenesis of asthma and asthma exacerbations. The role of ILC2s in virus-induced asthma exacerbations is not well-characterized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::498121463a7b8682bb4b9fa01c689153
http://hdl.handle.net/10044/1/92512
http://hdl.handle.net/10044/1/92512
Autor:
Jaideep Dhariwal, Aoife Cameron, Ernie Wong, Malte Paulsen, Maria-Belen Trujillo-Torralbo, Ajerico del Rosario, Eteri Bakhsoliani, Tatiana Kebadze, Mark Almond, Hugo Farne, Leila Gogsadze, Julia Aniscenko, Batika M. J. Rana, Trevor T. Hansel, David J. Jackson, Onn Min Kon, Michael R. Edwards, Roberto Solari, David J. Cousins, Ross P. Walton, Sebastian L. Johnston, Paul Lavender, Hannah Gould, David Cousins, Antoon J. van Oosterhout, Nathan W. Bartlett, Patrick Mallia, Jerico del Rosario, Janet L. Smith, Matthew J. Edwards, Karen Affleck, Nil Turan Jurdzinski, Veronique Birault, Peter McErlean, Yu-Chang Wu, Nadine Upton, Ismael Ranz Jimenez
Publikováno v:
Am J Respir Crit Care Med
RATIONALE: Type 2 innate lymphoid cells (ILC2s) are significant sources of type 2 cytokines, which are implicated in the pathogenesis of asthma and asthma exacerbations. The role of ILC2s in virus-induced asthma exacerbations is not well characterize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::816761f5244c7709ec80777271040f45
https://europepmc.org/articles/PMC8786078/
https://europepmc.org/articles/PMC8786078/
Autor:
Sebastian L. Johnston, Anton S. Dvornikov, Rudolf Valenta, A A Nikonova, Stephanie Traub, Dmitriy A. Kudlay, Maria-Belen Trujillo-Torralbo, Rahim Khaitov, Musa Khaitov, David A. Jackson, Luminita A. Stanciu, Ajerico del-Rosario
Publikováno v:
EBioMedicine
EBioMedicine, Vol 54, Iss, Pp-(2020)
EBioMedicine, Vol 54, Iss, Pp-(2020)
Background: Macrophages (Mф) can be M1/M2 polarized by Th1/2 signals, respectively. M2-like Mф are thought to be important in asthma pathogenesis, and M1-like in anti-infective immunity, however their roles in virus-induced asthma exacerbations are
Autor:
Tatiana Kebadze, W. Eugene Ho, Cheng Chang, Aurica G. Telcian, Peter J. Barnes, W.S. Fred Wong, Kazuhiro Ito, Ian M. Adcock, Patrick Mallia, Ajerico del Rosario, Luminita A. Stanciu, Julia Aniscenko, Joseph Footitt, Maria-Belen Trujillo-Torralbo, Sarah L. Elkin, Hong Yong Peh, Sebastian L. Johnston, Sarah Essilfie-Quaye, Onn Min Kon, Andrew L. Durham
Publikováno v:
Chest
Background Respiratory virus infections are commonly associated with COPD exacerbations, but little is known about the mechanisms linking virus infection to exacerbations. Pathogenic mechanisms in stable COPD include oxidative and nitrosative stress
Autor:
Rudolf Valenta, Sebastian L. Johnston, Katarzyna Niespodziana, Clarissa R. Cabauatan, Daniela Gallerano, Patrick Mallia, Ajerico del Rosario, David A. Jackson, Belen Trujillo-Torralbo
Publikováno v:
EBioMedicine, Vol 2, Iss 1, Pp 64-70 (2015)
Background: Rhinoviruses (RVs) are a major cause of common colds and induce exacerbations of asthma and chronic inflammatory lung diseases. Methods: We expressed and purified recombinant RV coat proteins VP1-4, non-structural proteins as well as N-te
Autor:
Michael R. Edwards, Musa Khaitov, Sarah L. Elkin, Joseph Footitt, Onn Min Kon, Stephanie Traub, Jonathan Macintyre, Sebastian L. Johnston, A A Nikonova, Maria Belen Trujillo-Torralbo, Max Habibi, Suzie Hingley-Wilson, Ajerico del Rosario, Patrick Mallia, Annemarie Sykes, Nadine Upton, David A. Jackson, Luminita A. Stanciu
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183864 (2017)
PLoS ONE
PLoS ONE
Rhinovirus infection is associated with the majority of asthma exacerbations. The role of fractalkine in anti-viral (type 1) and pathogenic (type 2) responses to rhinovirus infection in allergic asthma is unknown. To determine whether (1) fractalkine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d20ca27cbbac35bacc42d3520a2fcbe
https://surrey.eprints-hosting.org/844666/
https://surrey.eprints-hosting.org/844666/
Autor:
Batika M. J. Rana, Aoife Cameron, David J. Cousins, Ajerico del Rosario, Trevor T. Hansel, David A. Jackson, Eteri Bakhsoliani, Jaideep Dhariwal, Michael R. Edwards, Malte Paulsen, Maria-Belen Trujillo-Torralbo, Ross P. Walton, Sebastian L. Johnston
RATIONALE: Newly characterised type 2 innate lymphoid cells display potent type 2 effector functionality, however their contribution to allergic airways inflammation and asthma is poorly understood. Mucosal biopsy used to characterise the airway muco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31804b0252d5a11b9591737029f26cb5
http://hdl.handle.net/10044/1/44042
http://hdl.handle.net/10044/1/44042