Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Ajeet Rijal Upadhaya"'
Autor:
Dietmar Rudolf Thal, Alicja Ronisz, Thomas Tousseyn, Ajeet Rijal Upadhaya, Karthikeyan Balakrishnan, Rik Vandenberghe, Mathieu Vandenbulcke, Christine A. F. von Arnim, Markus Otto, Thomas G. Beach, Johan Lilja, Kerstin Heurling, Aruna Chakrabarty, Azzam Ismail, Christopher Buckley, Adrian P. L. Smith, Sathish Kumar, Gill Farrar, Jochen Walter
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-3 (2020)
An amendment to this paper has been published and can be accessed via the original article.
Externí odkaz:
https://doaj.org/article/19a76cce91414f4fae4b5e95015a403f
Autor:
Dietmar Rudolf Thal, Alicja Ronisz, Thomas Tousseyn, Ajeet Rijal Upadhaya, Karthikeyan Balakrishnan, Rik Vandenberghe, Mathieu Vandenbulcke, Christine A. F. von Arnim, Markus Otto, Thomas G. Beach, Johan Lilja, Kerstin Heurling, Aruna Chakrabarty, Azzam Ismail, Christopher Buckley, Adrian P. L. Smith, Sathish Kumar, Gill Farrar, Jochen Walter
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-16 (2019)
Abstract Alzheimer’s disease (AD)-related amyloid β-peptide (Aβ) pathology in the form of amyloid plaques and cerebral amyloid angiopathy (CAA) spreads in its topographical distribution, increases in quantity, and undergoes qualitative changes in
Externí odkaz:
https://doaj.org/article/4744e4e5830049b6bd05ed72d413054b
Autor:
Xiaohang Li, Simona Ospitalieri, Tessa Robberechts, Linda Hofmann, Christina Schmid, Ajeet Rijal Upadhaya, Marta J Koper, Christine A F von Arnim, Sathish Kumar, Michael Willem, Kathrin Gnoth, Meine Ramakers, Joost Schymkowitz, Frederic Rousseau, Jochen Walter, Alicja Ronisz, Karthikeyan Balakrishnan, Dietmar Rudolf Thal
Publikováno v:
Brain
Alzheimer’s disease is neuropathologically characterized by the deposition of the amyloid β-peptide (Aβ) as amyloid plaques. Aβ plaque pathology starts in the neocortex before it propagates into further brain regions. Moreover, Aβ aggregates un
Autor:
Jochen Walter, Aruna Chakrabarty, Christine A. F. von Arnim, Adrian Smith, Kerstin Heurling, Thomas G. Beach, Azzam Ismail, Mathieu Vandenbulcke, Ajeet Rijal Upadhaya, Johan Lilja, Karthikeyan Balakrishnan, Gill Farrar, Rik Vandenberghe, Sathish Kumar, Alicja Ronisz, Thomas Tousseyn, Christopher Buckley, Markus Otto, Dietmar Rudolf Thal
Publikováno v:
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-3 (2020)
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-3 (2020)
Alzheimer’s disease (AD)-related amyloid β-peptide (Aβ) pathology in the form of amyloid plaques and cerebral amyloid angiopathy (CAA) spreads in its topographical distribution, increases in quantity, and undergoes qualitative changes in its comp
Autor:
Christine A. F. von Arnim, Estifanos Ghebremedhin, Jochen Walter, Ajeet Rijal Upadhaya, Janina Gerth, Dietmar Rudolf Thal, Sathish Kumar
Publikováno v:
Annals of Clinical and Translational Neurology
OBJECTIVE: Amyloid β (Aβ) depositions in plaques and cerebral amyloid angiopathy (CAA) represent common features of Alzheimer's disease (AD). Sequential deposition of post-translationally modified Aβ in plaques characterizes distinct biochemical s
Autor:
Thomas Tousseyn, Julia Reichwald, Pablo Largo-Barrientos, Michael Willem, Rik Vandenberghe, Valerie Uytterhoeven, Luis Aragão Gomes, Karthikeyan Balakrishnan, Simona Ospitalieri, Matthias Staufenbiel, Marta J. Koper, Dietmar Rudolf Thal, Christine A. F. von Arnim, Silvia Andrea Hipp, Ajeet Rijal Upadhaya, Sabine Rabe, Regina Feederle, Camilla Giudici
Publikováno v:
Acta neuropathologica 138(6), 913-941 (2019). doi:10.1007/s00401-019-02053-5
Extracellular deposition of amyloid β-protein (Aβ) in amyloid plaques and intracellular accumulation of abnormally phosphorylated τ-protein (p-τ) in neurofibrillary tangles (NFTs) represent pathological hallmark lesions of Alzheimer's disease (AD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0988c1094b4b3748be0fb9f28ff3dc0a
https://lirias.kuleuven.be/handle/123456789/640169
https://lirias.kuleuven.be/handle/123456789/640169
Autor:
Thal, Dietmar, Ronisz, Alicja, Tousseyn, Thomas, Ajeet Rijal Upadhaya, Karthikeyan Balakrishnan, Vandenberghe, Rik, Vandenbulcke, Mathieu, Arnim, Christine Von, Otto, Markus, Beach, Thomas, Lilja, Johan, Heurling, Kerstin, Chakrabarty, Aruna, Ismail, Azzam, Buckley, Christopher, Smith, Adrian, Sathish Kumar, Farrar, Gill, Walter, Jochen
Additional file 1: Table S1. List of antibodies and silver techniques. IHC = immunohistochemistry, WB = western blotting. Table S2. Assessment of topographical distribution of Aβ plaques (a-d), CAA (a, e), and CAA severity [80] (a, f). Tissue-block
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d110d200bb4cf094b623bdeb3cbd618
Autor:
Ajeet Rijal Upadhaya, Christine A. F. von Arnim, W. Sue T. Griffin, Haruyasu Yamaguchi, Johannes Attems, Robert E. Mrak, Dietmar Rudolf Thal
Publikováno v:
European Archives of Psychiatry and Clinical Neuroscience. 263:137-145
Alzheimer's disease (AD) is characterized neuropathologically by the presence of amyloid plaques, neuritic plaques, and neurofibrillary tangles (NFTs). These lesions occur not only in demented individuals with AD but also in non-demented persons. In
Autor:
Estibaliz Capetillo-Zarate, Ajeet Rijal Upadhaya, Matthias Staufenbiel, Marcus Fändrich, Jochen Walter, Dietmar Rudolf Thal, Dorothee Abramowski, Haruyasu Yamaguchi, Irina Kosterin, Sathish Kumar
Publikováno v:
Neurobiology of Aging. 33:2641-2660
Soluble amyloid β-protein (Aβ) aggregates have been identified in the Alzheimer's disease (AD) brain. Dispersed Aβ aggregates in the brain parenchyma are different from soluble, membrane-associated and plaque-associated solid aggregates. They are
Autor:
Marcus Fändrich, Ajeet Rijal Upadhaya, Haruyasu Yamaguchi, Irina Lungrin, Dietmar Rudolf Thal
Publikováno v:
Journal of Cellular and Molecular Medicine
Alzheimer's disease (AD) is characterized by the aggregation and deposition of amyloid β protein (Aβ) in the brain. Soluble Aβ oligomers are thought to be toxic. To investigate the predominant species of Aβ protein that may play a role in AD path