Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ajeesh Vengamthodi"'
Autor:
Anusree Venkidath, Jong Min Oh, Sanal Dev, Elham Amin, Shebina P. Rasheed, Ajeesh Vengamthodi, Nicola Gambacorta, Ahmed Khames, Mohamed A. Abdelgawad, Ginson George, Orazio Nicolotti, Hoon Kim, Bijo Mathew
Publikováno v:
Molecules, Vol 26, Iss 19, p 6004 (2021)
A small series of nitro group-bearing enamides was designed, synthesized (NEA1–NEA5), and evaluated for their inhibitory profiles of monoamine oxidases (MAOs) and β-site amyloid precursor protein cleaving enzyme 1 (β-secretase, BACE1). Compounds
Externí odkaz:
https://doaj.org/article/4a8c83f6538c49de905897cb6b8edc72
Autor:
Rinshana Fathima Abdul Azeez, Susi Zara, Alessia Ricci, Sanal Dev, Ajeesh Vengamthodi, Fathima Sahla Kavully, Raihan Arikkattel Abdu, Kadeeja Thottungal Kalathil, Mohamed A. Abdelgawad, Bijo Mathew, Simone Carradori
Publikováno v:
Research on Chemical Intermediates. 49:203-220
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::371fe9bb67572b6c1cf42be90cc98749
https://doi.org/10.1007/s11164-022-04864-w
https://doi.org/10.1007/s11164-022-04864-w
Elevated total cholesterol is a major cause of heart disease and stroke in both developed and developing countries. Hyperlipidemia and atherosclerosis cause around 30% of ischemic heart disease. (WHO) Low HDL and high LDL and VLDL caused CVD before.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e387ad7a4f88d8da2a6a7f59f56d68c3
https://doi.org/10.21203/rs.3.rs-2736087/v1
https://doi.org/10.21203/rs.3.rs-2736087/v1
Autor:
Rinshana Fathima Abdul Azeez, Ajeesh Vengamthodi, Bijo Mathew, Fathima Sahla Kavully, Anna Rita Tondo, Sanal Dev, Swafvan Kaipakasseri, Hoon Kim, Ashique Palakkathondi, Jong Min Oh, Orazio Nicolotti
Publikováno v:
Journal of Pharmacy and Pharmacology. 72:916-926
ObjectivesTo develop of new class of selective and reversible MAO-B inhibitors from enamides.MethodsSyntheses of the titled derivatives (AD1–AD11) were achieved by reacting cinnamoyl chloride and various primary and secondary amines in basic medium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06872ea8d04d19a86b31bb2fa395ef69
https://doi.org/10.1111/jphp.13264
https://doi.org/10.1111/jphp.13264
Autor:
Sanal Dev, Anusree Venkidath, Bijo Mathew, Shebina P Rasheed, Nicola Gambacorta, Jong Min Oh, Ginson George, Hoon Kim, Ajeesh Vengamthodi, Ahmed Khames, Orazio Nicolotti, Mohamed A. Abdelgawad, Elham Amin
Publikováno v:
Molecules
Volume 26
Issue 19
Molecules, Vol 26, Iss 6004, p 6004 (2021)
Volume 26
Issue 19
Molecules, Vol 26, Iss 6004, p 6004 (2021)
A small series of nitro group-bearing enamides was designed, synthesized (NEA1–NEA5), and evaluated for their inhibitory profiles of monoamine oxidases (MAOs) and β-site amyloid precursor protein cleaving enzyme 1 (β-secretase, BACE1). Compounds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bc1558c8dfc7b9cd1784173697d4b71
https://pubmed.ncbi.nlm.nih.gov/34641548
https://pubmed.ncbi.nlm.nih.gov/34641548
Autor:
Ruchi Malik, Manish Sharma, Bhanwar Singh Choudhary, Ajeesh Vengamthodi, Shubham Srivastava, Inderpal Singh
Publikováno v:
Structural Chemistry. 30:1761-1778
The PI3KCA gene functions by activating cascade signaling pathways leading to cell proliferation, survival, and growth. Being one of the frequently aberrant kinase in various malignancies, isoform selectivity among kinases remains a challenging aspec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d9cbe3ddfede8918699c4c1d8eb2ffe
https://doi.org/10.1007/s11224-019-01303-2
https://doi.org/10.1007/s11224-019-01303-2