Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Ajda Çoker Gürkan"'
Autor:
ÖZGE RENCÜZOĞULLARI, SELAY TORNACI, YAĞMUR ÇELİK, NAYAT NAROT TAŞ, PINAR OBAKAN YERLİKAYA, ELİF DAMLA ARISAN, AJDA ÇOKER GÜRKAN
Publikováno v:
Turkish Journal of Biology. 47:29-43
Human growth hormone (GH) is crucial modulator of cellular metabolisms, including cell proliferation and organ development, by stimulating insulin-like growth factor-1 (IGF-1), which has various functions such as cell proliferation, tissue growth, su
Autor:
Pınar Obakan Yerlikaya, Elif Arısan, Leila Mehdizadehtapeh, Pınar Uysal Onganer, Ajda Çoker Gürkan
Publikováno v:
European Journal of Biology.
Autor:
Pınar Obakan-Yerlikaya, Kaan Adacan, Elif Damla Arısan, Ajda Çoker-Gürkan, Narçın Palavan-Ünsal
Publikováno v:
Proceedings, Vol 1, Iss 10, p 986 (2017)
Epibrassinolide (EBR) is a natural plant polyhydroxysteroid with structural similarity to steroid hormones. Lately we showed by SILAC assay that EBR treatment induces apoptosis by significantly altering the expressions of proteins having role in unfo
Externí odkaz:
https://doaj.org/article/e0dd923e15d149728ea83505564b420e
Autor:
Ajda Çoker Gürkan, Merve Çelik, Merve Uğur, Elif Damla Arisan, Pinar Obakan Yerlikaya, Narçın Palavan Ünsal
Publikováno v:
Proceedings, Vol 1, Iss 10, p 989 (2017)
Autocrine Growth Hormone (GH) induces cell growth, proliferation metastasis in breast cancer. Curcumin is a promising therapeutic agent in cancer through affecting different molecular targets. Our aim was to demonstrate the molecular machinery of cur
Externí odkaz:
https://doaj.org/article/0fd083d2b08b4f29806fc82e4c471ee1
Autor:
Elif Damla Arisan, Özge Rencüzoğulları, Ajda Çoker-Gürkan, Pinar Obakan-Yerlikaya, Narçın Palavan-Ünsal
Publikováno v:
Proceedings, Vol 1, Iss 10, p 992 (2017)
FASN is key enzyme during lipid biogenesis is associated with prostate cancer. In this study, we aim to investigate the potential role of celastrol, root extracts of Tripterygium wilfordii on modulation of lipid biosynthesis-associated PI3K/Akt signa
Externí odkaz:
https://doaj.org/article/5ae60946402040aaa3fe63eb0e3b4202
Autor:
Elif Damla Arisan, Dilek Telci, Pınar Obakan Yerlikaya, Ozge Rencuzogullari, Ajda Çoker Gürkan
Publikováno v:
Journal of Cellular Biochemistry. 121:508-523
The mortality rate of pancreatic cancer has close parallels to its incidence rate because of limited therapeutics and lack of effective prognosis. Despite various novel chemotherapeutics combinations, the 5-year survival rate is still under 5%. In th
Autor:
Melissa Kara, Osman Orcun Okumus, Pınar Obakan Yerlikaya, Utku Ozbey, Tugba Yenigun, Narcin Palavan Unsal, Ajda Çoker Gürkan, Elif Damla Arisan
Glycogen synthase kinase 3 beta (GSK3 beta) is considered an important element of glycogen metabolism; however, it has many other regulatory roles. Changes in the GSK3 beta signaling mechanism have been associated with various disorders, such as Alzh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85a1b74e0714af3dd60d7256a861a954
https://hdl.handle.net/11413/8225
https://hdl.handle.net/11413/8225
Autor:
Pınar Obakan Yerlikaya, Dilek Telci, Ajda Çoker Gürkan, Ozge Rencuzogullari, Elif Damla Arisan
Fatty acids (FAs) synthesis mechanism has various regulators such as fatty acid synthase (FASN), AMP-regulated protein kinase (AMPK), or mammalian target of rapamycin (mTOR), which are aberrantly dysregulated in various pancreatic cancer cells. In th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8b795e34eea571de74828f8ef03fef5
https://aperta.ulakbim.gov.tr/record/230638
https://aperta.ulakbim.gov.tr/record/230638
Autor:
Elif Damla Arisan, Ajda Çoker Gürkan, Pelin Ozfiliz Kilbas, Pınar Obakan Yerlikaya, Sina Kashani
Publikováno v:
Proceedings, Vol 40, Iss 1, p 42 (2020)
Prostate cancer is the second common cause of death among men worldwide. In the treatment of prostate cancer, conventional chemotherapeutics are commonly used. The plant alkaloid Paclitaxel and platinum-based cisplatin are the most common chemotherap
Autor:
Elif Damla Arisan, Pelin Ozfiliz Kilbas, Pinar Uysal-Onganer, Ozlem Sonmez, Pınar Obakan Yerlikaya, Ajda Çoker Gürkan
Publikováno v:
Biology
Volume 9
Issue 10
Biology, Vol 9, Iss 320, p 320 (2020)
Volume 9
Issue 10
Biology, Vol 9, Iss 320, p 320 (2020)
Simple Summary Investigation into effective targets of drug resistance is important for identifying novel strategies in cancer therapy. The study aimed to determine the functional role of paclitaxel (PTX) resistance on MCF-7 cell survival related to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86f930139d091f1d2ed29e2492a907cd
https://doi.org/10.3390/biology9100320
https://doi.org/10.3390/biology9100320