Výsledky vyhledávání - "Ajay Singh Tanwar"

Akademický článek

Importance of hydrophobic cavities in allosteric regulation of formylglycinamide synthetase: insight from xenon trapping and statistical coupling analysis.

Autor: Ajay Singh Tanwar, Venuka Durani Goyal, Deepanshu Choudhary, Santosh Panjikar, Ruchi Anand

Publikováno v: PLoS ONE, Vol 8, Iss 11, p e77781 (2013)

Formylglycinamide ribonucleotide amidotransferase (FGAR-AT) is a 140 kDa bi-functional enzyme involved in a coupled reaction, where the glutaminase active site produces ammonia that is subsequently utilized to convert FGAR to its corresponding amidin

Externí odkaz: https://doaj.org/article/69cee2ef50614263914e6d8c160a69a9

Zobrazit plný text záznamu

Identification of Function and Mechanistic Insights of Guanine Deaminase from Nitrosomonas europaea: Role of the C-Terminal Loop in Catalysis

Autor: Ruchi Anand, Ajay Singh Tanwar, Aruna Bitra, Bhukya Hussain

Publikováno v: Biochemistry. 52:3512-3522

NE0047 from Nitrosomonas europaea has been annotated as a zinc-dependent deaminase; however, the substrate specificity is unknown because of the low level of structural similarity and sequence identity compared to other family members. In this study,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17f83fe8576d266a7872e3c69e22d6c9
https://doi.org/10.1021/bi400068g

Zobrazit plný text záznamu

Determination of the Formylglycinamide Ribonucleotide.Amidotransferase Ammonia Pathway by Combining 3D-RISM Theory with Experiment

Autor: Daniel J. Sindhikara, Fumio Hirata, Ruchi Anand, Ajay Singh Tanwar

Publikováno v: IndraStra Global.

Molecular tunnels in enzyme systems possess variable architecture and are therefore difficult to predict. In this work, we design and apply an algorithm to resolve the pathway followed by ammonia using the bifunctional enzyme formylglycinamide ribonu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c039fce8265b0255339a813b20f61f8
https://igi.indrastra.com/items/show/57899

Zobrazit plný text záznamu

Communication between the two catalytic domains of formylglycinamide ribonucleotide amidotransferase

Autor: Nandini, Ajay Singh Tanwar, Ruchi Anand

Publikováno v: Acta Crystallographica Section A Foundations and Advances. 73:C1176-C1176

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::538d3ee379b2d1cf5d5c98485afa7919
https://doi.org/10.1107/s205327331708398x

Zobrazit plný text záznamu

Formylglycinamide ribonucleotide amidotransferase from Salmonella typhimurium: role of ATP complexation and the glutaminase domain in catalytic coupling

Autor: Santosh Panjikar, Ruchi Anand, Ajay Singh Tanwar, Marya Morar

Publikováno v: Acta crystallographica. Section D, Biological crystallography. 68(Pt 6)

Formylglycinamide ribonucleotide (FGAR) amidotransferase (FGAR-AT) takes part in purine biosynthesis and is a multidomain enzyme with multiple spatially separated active sites. FGAR-AT contains a glutaminase domain that is responsible for the generat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c6b03a83f3b5106f0d8b67368eea763
https://pubmed.ncbi.nlm.nih.gov/22683785

Zobrazit plný text záznamu

Importance of Hydrophobic Cavities in Allosteric Regulation of Formylglycinamide Synthetase: Insight from Xenon Trapping and Statistical Coupling Analysis

Autor: Venuka Durani Goyal, Deepanshu Choudhary, Santosh Panjikar, Ruchi Anand, Ajay Singh Tanwar

Publikováno v: 'PloS One ', vol: 8, pages: e77781-1-e77781-13 (2013)
PLoS ONE, Vol 8, Iss 11, p e77781 (2013)
PLoS ONE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c52b944bd7ab88e4336ccb6ae454f657
https://doi.org/10.1371/journal.pone.0077781

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání