Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Ajay S Gulati"'
Autor:
Gregory A Taylor, Hsin-I Huang, Brian E Fee, Nourhan Youssef, Mark L Jewell, Viviana Cantillana, Alexi A Schoenborn, Allison R Rogala, Anne F Buckley, Carl G Feng, Bruce A Vallance, Ajay S Gulati, Gianna E Hammer
Publikováno v:
PLoS Pathogens, Vol 16, Iss 5, p e1008553 (2020)
IRGM and its mouse orthologue Irgm1 are dynamin-like proteins that regulate vesicular remodeling, intracellular microbial killing, and pathogen immunity. IRGM dysfunction is linked to inflammatory bowel disease (IBD), and while it is thought that def
Externí odkaz:
https://doaj.org/article/0f551c4084a24ce09013efa7ff036e98
Autor:
Ellen Li, Christina M Hamm, Ajay S Gulati, R Balfour Sartor, Hongyan Chen, Xiao Wu, Tianyi Zhang, F James Rohlf, Wei Zhu, Chi Gu, Charles E Robertson, Norman R Pace, Edgar C Boedeker, Noam Harpaz, Jeffrey Yuan, George M Weinstock, Erica Sodergren, Daniel N Frank
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e26284 (2012)
We tested the hypothesis that Crohn's disease (CD)-related genetic polymorphisms involved in host innate immunity are associated with shifts in human ileum-associated microbial composition in a cross-sectional analysis of human ileal samples. Sanger
Externí odkaz:
https://doaj.org/article/c0f222c346084027b069328b2cde39b9
Autor:
Ajay S Gulati, Michael T Shanahan, Janelle C Arthur, Emily Grossniklaus, Richard J von Furstenberg, Lieselotte Kreuk, Susan J Henning, Christian Jobin, R Balfour Sartor
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e32403 (2012)
Increasing evidence supports the central role of Paneth cells in maintaining intestinal host-microbial homeostasis. However, the direct impact of host genotype on Paneth cell function remains unclear. Here, we characterize key differences in Paneth c
Externí odkaz:
https://doaj.org/article/f7b812795bde4fb9a4bfa0d87c634e46
Autor:
Natasa Giallourou, Jason Arnold, Elizabeth T. Rogawski McQuade, Muyiwa Awoniyi, Rose Viguna Thomas Becket, Kenneth Walsh, Jeremy Herzog, Ajay S. Gulati, Ian M. Carroll, Stephanie Montgomery, Pedro Henrique Quintela, Angela M. Faust, Steven M. Singer, Anthony A. Fodor, Tahmeed Ahmad, Mustafa Mahfuz, Esto Mduma, Thomas Walongo, Richard L. Guerrant, R. Balfour Sartor, Jonathan R. Swann, Margaret N. Kosek, Luther A. Bartelt
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Giardia lamblia (Giardia) is among the most common intestinal pathogens in children in low- and middle-income countries (LMICs). Although Giardia associates with early-life linear growth restriction, mechanistic explanations for Giardia-asso
Externí odkaz:
https://doaj.org/article/80ad1c0a8c014079ba7ab235aa81ba3b
Autor:
Vivian H. Lee, Ajay S. Gulati
Publikováno v:
Current opinion in gastroenterology. 38(6)
Paneth cells are specialized, secretory epithelial cells located in the small intestine. Although their existence was first described in 1872, their precise role in the gut remained unclear for over a century. Over the past few decades, elegant studi
Autor:
Matthew H. Foley, Morgan E. Walker, Allison K. Stewart, Sarah O’Flaherty, Emily C. Gentry, Shakshi Patel, Violet V. Beaty, Garrison Allen, Meichen Pan, Joshua B. Simpson, Caroline Perkins, Molly E. Vanhoy, Michael K. Dougherty, Sarah K. McGill, Ajay S. Gulati, Pieter C. Dorrestein, Erin S. Baker, Matthew R. Redinbo, Rodolphe Barrangou, Casey M. Theriot
Publikováno v:
Nature Microbiology. 8:611-628
Bile acids (BAs) mediate the crosstalk between human and microbial cells and influence diseases including Clostridioides difficile infection (CDI). While bile salt hydrolases (BSHs) shape the BA pool by deconjugating conjugated BAs, the basis for the
Autor:
Kevin M. Byrd, Ajay S. Gulati
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
In modern medicine, the oral cavity has often been viewed as a passive conduit to the upper airways and gastrointestinal tract; however, its connection to the rest of the body has been increasingly explored over the last 40 years. For several disease
Externí odkaz:
https://doaj.org/article/dccbdecda73d41b2bb26fa1abd8b6122
Publikováno v:
Surgical Clinics of North America. 102:913-927
Key differences exist in pediatric and adult inflammatory bowel disease (IBD), and a multidisciplinary approach focused on meeting these needs should be implemented. In an emergency situation, surgical management of pediatric IBD should focus on pati
Autor:
Michael D. Kappelman, David A. Wohl, Hans H. Herfarth, Ann M. Firestine, Jeremy Adler, Rana F. Ammoury, Jeanine E. Aronow, Dorsey M. Bass, Julie A. Bass, Keith Benkov, Catalina Berenblum Tobi, Margie E. Boccieri, Brendan M. Boyle, William B. Brinkman, Jose M. Cabera, Kelly Chun, Richard B. Colletti, Cassandra M. Dodds, Jill M. Dorsey, Dawn R. Ebach, Edurne Entrena, Christopher B. Forrest, Joseph A. Galanko, John E. Grunow, Ajay S. Gulati, Anastasia Ivanova, Traci W. Jester, Jess L. Kaplan, Subra Kugathasan, Mark E. Kusek, Ian H. Leibowitz, Tiffany M. Linville, Ellen A. Lipstein, Peter A. Margolis, Phillip Minar, Zarela Molle-Rios, Jonathan Moses, Kelly K. Olano, Lourdes Osaba, Pablo J. Palomo, Helen Pappa, K.T. Park, Dinesh S. Pashankar, Lisa Pitch, Michelle Robinson, Charles M. Samson, Kelly C. Sandberg, Julia R. Schuchard, Michael Seid, Kimberly A. Shelly, Steven J. Steiner, Jennifer A. Strople, Jillian S. Sullivan, Jeanne Tung, Prateek Wali, Michael Zikry, Morris Weinberger, Shehzad A. Saeed, Athos Bousvaros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0c20a41033da7f74265ab90ee62a011
https://doi.org/10.2139/ssrn.4352561
https://doi.org/10.2139/ssrn.4352561
Publikováno v:
The American journal of gastroenterology.
Fecal microbiota transplantation (FMT) is a rapidly growing therapy aimed at reconstituting the dysbiotic microbiota of a patient with the beneficial stool microbiota of a healthy individual. The efficacy rates of FMT are very robust for recurrent Cl