Zobrazeno 1 - 10
of 125
pro vyhledávání: '"Ajay S Gulati"'
Autor:
Natasa Giallourou, Jason Arnold, Elizabeth T. Rogawski McQuade, Muyiwa Awoniyi, Rose Viguna Thomas Becket, Kenneth Walsh, Jeremy Herzog, Ajay S. Gulati, Ian M. Carroll, Stephanie Montgomery, Pedro Henrique Quintela, Angela M. Faust, Steven M. Singer, Anthony A. Fodor, Tahmeed Ahmad, Mustafa Mahfuz, Esto Mduma, Thomas Walongo, Richard L. Guerrant, R. Balfour Sartor, Jonathan R. Swann, Margaret N. Kosek, Luther A. Bartelt
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Giardia lamblia (Giardia) is among the most common intestinal pathogens in children in low- and middle-income countries (LMICs). Although Giardia associates with early-life linear growth restriction, mechanistic explanations for Giardia-asso
Externí odkaz:
https://doaj.org/article/80ad1c0a8c014079ba7ab235aa81ba3b
Autor:
Takahiko Toyonaga, Kenza C. Araba, Meaghan M. Kennedy, Benjamin P. Keith, Elisabeth A. Wolber, Caroline Beasley, Erin C. Steinbach, Matthew R. Schaner, Animesh Jain, Millie D. Long, Edward L. Barnes, Hans H. Herfarth, Kim L. Isaacs, Jonathan J. Hansen, Muneera R. Kapadia, José Gaston Guillem, Ajay S. Gulati, Praveen Sethupathy, Terrence S. Furey, Camille Ehre, Shehzad Z. Sheikh
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract The host receptor for SARS-CoV-2, angiotensin-converting enzyme 2 (ACE2), is highly expressed in small intestine. Our aim was to study colonic ACE2 expression in Crohn's disease (CD) and non-inflammatory bowel disease (non-IBD) controls. We
Externí odkaz:
https://doaj.org/article/46dc769554ff4a93a33f60385762e0c7
Autor:
Vivian H. Lee, Ajay S. Gulati
Publikováno v:
Current opinion in gastroenterology. 38(6)
Paneth cells are specialized, secretory epithelial cells located in the small intestine. Although their existence was first described in 1872, their precise role in the gut remained unclear for over a century. Over the past few decades, elegant studi
Autor:
Matthew H. Foley, Morgan E. Walker, Allison K. Stewart, Sarah O’Flaherty, Emily C. Gentry, Shakshi Patel, Violet V. Beaty, Garrison Allen, Meichen Pan, Joshua B. Simpson, Caroline Perkins, Molly E. Vanhoy, Michael K. Dougherty, Sarah K. McGill, Ajay S. Gulati, Pieter C. Dorrestein, Erin S. Baker, Matthew R. Redinbo, Rodolphe Barrangou, Casey M. Theriot
Publikováno v:
Nature Microbiology. 8:611-628
Bile acids (BAs) mediate the crosstalk between human and microbial cells and influence diseases including Clostridioides difficile infection (CDI). While bile salt hydrolases (BSHs) shape the BA pool by deconjugating conjugated BAs, the basis for the
Autor:
Kevin M. Byrd, Ajay S. Gulati
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
In modern medicine, the oral cavity has often been viewed as a passive conduit to the upper airways and gastrointestinal tract; however, its connection to the rest of the body has been increasingly explored over the last 40 years. For several disease
Externí odkaz:
https://doaj.org/article/dccbdecda73d41b2bb26fa1abd8b6122
Autor:
Gregory A Taylor, Hsin-I Huang, Brian E Fee, Nourhan Youssef, Mark L Jewell, Viviana Cantillana, Alexi A Schoenborn, Allison R Rogala, Anne F Buckley, Carl G Feng, Bruce A Vallance, Ajay S Gulati, Gianna E Hammer
Publikováno v:
PLoS Pathogens, Vol 16, Iss 5, p e1008553 (2020)
IRGM and its mouse orthologue Irgm1 are dynamin-like proteins that regulate vesicular remodeling, intracellular microbial killing, and pathogen immunity. IRGM dysfunction is linked to inflammatory bowel disease (IBD), and while it is thought that def
Externí odkaz:
https://doaj.org/article/0f551c4084a24ce09013efa7ff036e98
Publikováno v:
Surgical Clinics of North America. 102:913-927
Key differences exist in pediatric and adult inflammatory bowel disease (IBD), and a multidisciplinary approach focused on meeting these needs should be implemented. In an emergency situation, surgical management of pediatric IBD should focus on pati
Autor:
Renee L. Greer, Xiaoxi Dong, Ana Carolina F. Moraes, Ryszard A. Zielke, Gabriel R. Fernandes, Ekaterina Peremyslova, Stephany Vasquez-Perez, Alexi A. Schoenborn, Everton P. Gomes, Alexandre C. Pereira, Sandra R. G. Ferreira, Michael Yao, Ivan J. Fuss, Warren Strober, Aleksandra E. Sikora, Gregory A. Taylor, Ajay S. Gulati, Andrey Morgun, Natalia Shulzhenko
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Mice deficient in the pro-inflammatory cytokine IFNγ have improved glucose tolerance. Here, the authors show that this effect depends on the gut microbeAkkermansia muciniphila, whose abundance increases in the absence IFNγ, and which is known to ha
Externí odkaz:
https://doaj.org/article/61494a965e404846a44ae00fc93376f4
Autor:
Michael D. Kappelman, David A. Wohl, Hans H. Herfarth, Ann M. Firestine, Jeremy Adler, Rana F. Ammoury, Jeanine E. Aronow, Dorsey M. Bass, Julie A. Bass, Keith Benkov, Catalina Berenblum Tobi, Margie E. Boccieri, Brendan M. Boyle, William B. Brinkman, Jose M. Cabera, Kelly Chun, Richard B. Colletti, Cassandra M. Dodds, Jill M. Dorsey, Dawn R. Ebach, Edurne Entrena, Christopher B. Forrest, Joseph A. Galanko, John E. Grunow, Ajay S. Gulati, Anastasia Ivanova, Traci W. Jester, Jess L. Kaplan, Subra Kugathasan, Mark E. Kusek, Ian H. Leibowitz, Tiffany M. Linville, Ellen A. Lipstein, Peter A. Margolis, Phillip Minar, Zarela Molle-Rios, Jonathan Moses, Kelly K. Olano, Lourdes Osaba, Pablo J. Palomo, Helen Pappa, K.T. Park, Dinesh S. Pashankar, Lisa Pitch, Michelle Robinson, Charles M. Samson, Kelly C. Sandberg, Julia R. Schuchard, Michael Seid, Kimberly A. Shelly, Steven J. Steiner, Jennifer A. Strople, Jillian S. Sullivan, Jeanne Tung, Prateek Wali, Michael Zikry, Morris Weinberger, Shehzad A. Saeed, Athos Bousvaros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0c20a41033da7f74265ab90ee62a011
https://doi.org/10.2139/ssrn.4352561
https://doi.org/10.2139/ssrn.4352561
Publikováno v:
The American journal of gastroenterology.
Fecal microbiota transplantation (FMT) is a rapidly growing therapy aimed at reconstituting the dysbiotic microbiota of a patient with the beneficial stool microbiota of a healthy individual. The efficacy rates of FMT are very robust for recurrent Cl