Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Ajay Ravindranathan"'
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0206525 (2018)
The telomerase enzyme enables unlimited proliferation of most human cancer cells by elongating telomeres and preventing replicative senescence. Despite the critical importance of telomerase in cancer biology, challenges detecting telomerase activity
Externí odkaz:
https://doaj.org/article/23f4602a981d4f73a9e08a199d54aae2
Autor:
Calixto-Hope G. Lucas, Emily A. Sloan, Rohit Gupta, Jasper Wu, Drew Pratt, Harish N. Vasudevan, Ajay Ravindranathan, Jairo Barreto, Erik A. Williams, Anny Shai, Nicholas S. Whipple, Carol S. Bruggers, Ossama Maher, Burt Nabors, Michael Rodriguez, David Samuel, Melandee Brown, Jason Carmichael, Rufei Lu, Kanish Mirchia, Daniel V. Sullivan, Melike Pekmezci, Tarik Tihan, Andrew W. Bollen, Arie Perry, Anuradha Banerjee, Sabine Mueller, Nalin Gupta, Shawn L. Hervey-Jumper, Nancy Ann Oberheim Bush, Mariza Daras, Jennie W. Taylor, Nicholas A. Butowski, John de Groot, Jennifer L. Clarke, David R. Raleigh, Joseph F. Costello, Joanna J. Phillips, Alyssa T. Reddy, Susan M. Chang, Mitchel S. Berger, David A. Solomon
Publikováno v:
Acta Neuropathologica. 144:747-765
Gliomas arising in the setting of neurofibromatosis type 1 (NF1) are heterogeneous, occurring from childhood through adulthood, can be histologically low-grade or high-grade, and follow an indolent or aggressive clinical course. Comprehensive profili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d9443b332541d26f7f773096d51b660
https://doi.org/10.1007/s00401-022-02478-5
https://doi.org/10.1007/s00401-022-02478-5
Autor:
Susan M. Chang, Rohit Gupta, Soonmee Cha, Huiling Xu, Melissa Gener, Jasper Wu, Nida Zia, Damien Kee, Ajay Ravindranathan, Kathan Shah, Calixto-Hope G Lucas, Arie Perry, David A. Solomon, Kevin Ginn, Nausheen Yaqoob, Adriana Florez, Jennifer Clarke, Jairo Barreto, Mitchel S. Berger, Owen W.J. Prall, Hyun S Ko
Publikováno v:
Acta Neuropathologica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7800479816bb9094a848affc74749b24
http://europepmc.org/articles/PMC8732961
http://europepmc.org/articles/PMC8732961
Autor:
Sariah Allen, Cassie Kline, Carole Brathwaite, Mouied Alashari, Gourish Mondal, Ajay Ravindranathan, Pamela Doo, Brent A. Orr, David A. Solomon, Patrick Devine, Javier Villanueva-Meyer, Joanna J. Phillips, Carol S. Bruggers, Alberto Broniscer, David Samuel, Ossama M. Maher, Jessica Van Ziffle, Alyssa Reddy, Tarik Tihan, Rong Li, Samuel H. Cheshier, Arie Perry, Nicholas S Whipple, Laura K. Metrock, Matthew Hall, James P. Grenert, Lee-Way Jin, Anu Banerjee, Andrew W. Bollen, Corey Raffel, Courtney Onodera, Julieann C. Lee, Quynh T. Tran, Melike Pekmezci, Mitchel S. Berger, Reuben Antony, Jairo Barreto, Minesh P. Mehta, Ziad Khatib, Rohit Gupta, John T. Lucas, Nalin Gupta
Publikováno v:
Acta Neuropathol
Acta neuropathologica, vol 139, iss 6
Acta neuropathologica, vol 139, iss 6
Brain tumors are the most common solid tumors of childhood, and the genetic drivers and optimal therapeutic strategies for many of the different subtypes remain unknown. Here, we identify that bithalamic gliomas harbor frequent mutations in the EGFR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e08e7c3b224d9f0dfed7d7aa0d94b0fe
https://pubmed.ncbi.nlm.nih.gov/32303840
https://pubmed.ncbi.nlm.nih.gov/32303840
Autor:
Poonam Vohra, Iwei Yeh, Boris C. Bastian, Su-Yang Liu, Elizabeth M. Hosfield, James P. Grenert, Bradley A. Stohr, Jessica Van Ziffle, Nancy M. Joseph, Nancy Y. Greenland, Eric Talevich, Courtney Onodera, Yunn-Yi Chen, Ajay Ravindranathan, Gregor Krings
Publikováno v:
Modern Pathology. 29:1012-1027
Malignant phyllodes tumors of the breast are poorly understood rare neoplasms with potential for aggressive behavior. Few efficacious treatment options exist for progressed or metastatic disease. The molecular features of malignant phyllodes tumors a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d9c5c8378187c983ecf83ecd929150e
https://doi.org/10.1038/modpathol.2016.97
https://doi.org/10.1038/modpathol.2016.97
Publikováno v:
PloS one, vol 13, iss 12
PLoS ONE, Vol 13, Iss 12, p e0206525 (2018)
PLoS ONE
PLoS ONE, Vol 13, Iss 12, p e0206525 (2018)
PLoS ONE
The telomerase enzyme enables unlimited proliferation of most human cancer cells by elongating telomeres and preventing replicative senescence. Despite the critical importance of telomerase in cancer biology, challenges detecting telomerase activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b35657be6bf4b62db3bcf3d35941028
https://escholarship.org/uc/item/05q452gm
https://escholarship.org/uc/item/05q452gm
Autor:
Khushbu Sharma, Ajay Ravindranathan, Feng Chen, Bradley A. Stohr, Hubert Y. Luu, Holger Willenbring, Bernadette Y. Hsu, Robert J. Jimenez
Publikováno v:
Cell Stem Cell
Cell stem cell, vol 26, iss 1
Cell stem cell, vol 26, iss 1
Hepatocyte proliferation is the principal mechanism for generating new hepatocytes in liver homeostasis and regeneration. Recent studies have suggested that this ability is not equally distributed among hepatocytes but concentrated in a small subset
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c14735abef594c3cef0f1534f519659
https://doi.org/10.1016/j.stem.2019.11.001
https://doi.org/10.1016/j.stem.2019.11.001
Publikováno v:
Alcoholism: Clinical and Experimental Research. 34:800-812
Background: Alcohol use disorders (AUD) exhibit the properties shared by common conditions and diseases classified as genetically complex. The etiology of AUDs is heterogeneous involving mostly unknown interactions of environmental and heritable fact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1b5d89e7c0aeea922ab694dfe7a5b42
https://doi.org/10.1111/j.1530-0277.2010.01152.x
https://doi.org/10.1111/j.1530-0277.2010.01152.x
Autor:
Ajay Ravindranathan, Margaret Robertson, Raymond L. White, Marc A. Schuckit, Jennifer L. Whistler, Geoff Joslyn
Publikováno v:
Proceedings of the National Academy of Sciences. 106:10811-10816
Opioids and their receptors have an important role in analgesia and alcohol and substance use disorders (ASUD). We have identified several naturally occurring amino acid changing variants of the human mu-opioid receptor (MOR), and assessed the functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2bc8a96ae08a64c175f2112c52f7315
https://doi.org/10.1073/pnas.0904509106
https://doi.org/10.1073/pnas.0904509106
Autor:
Ajay Ravindranathan, Tim York, Mary P. Cage, Michael F. Miles, Robnet T. Kerns, Sajida Hassan, Robert W. Williams, James M. Sikela
Publikováno v:
The Journal of Neuroscience. 25:2255-2266
Activation of the mesolimbic dopamine reward pathway by acute ethanol produces reinforcement and changes in gene expression that appear to be crucial to the molecular basis for adaptive behaviors and addiction. The inbred mouse strains DBA/2J and C57
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c9b38b740966f4b3999fa988350acc8
https://doi.org/10.1523/jneurosci.4372-04.2005
https://doi.org/10.1523/jneurosci.4372-04.2005