Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Ajay Padsalgikar"'
Autor:
Ajay Padsalgikar
Applications of Polyurethanes in Medical Devices provides detailed coverage of polyurethane (PU) chemistry, processing and preparation for performant medical devices. Polyurethanes have found many uses in medical applications, due to their biocompati
Autor:
Ajay Padsalgikar, Christopher R. Jenney, Ekaterina Tkatchouk, James Runt, Genevieve Gallagher, Ciprian Iacob
Publikováno v:
Journal of Biomedical Materials Research Part B: Applied Biomaterials. 105:1544-1558
Environmental stress cracking (ESC) was replicated in vitro on Optim™ (OPT) insulation, a polydimethylsiloxane-based polyurethane utilized clinically in cardiac leads, using a Zhao-type oxidation model. OPT performance was compared to that of two i
Autor:
Ekaterina Tkatchouk, Emily Chen, Ajay Padsalgikar, Nick Sears, Tyler Touchet, Alysha Kishan, Christopher R. Jenney, Elizabeth Cosgriff-Hernandez
Publikováno v:
Journal of Biomedical Materials Research Part A. 104:1805-1816
Although silicone-based polyurethanes have demonstrated increased oxidative stability, there have been conflicting reports of the long-term hydrolytic stability of Optim™ and PurSil(®) 35 based on recent temperature-accelerated hydrolysis studies.
Autor:
James Runt, Ajay Padsalgikar, John Rickard, Genevieve Gallagher, Bruce L. Wilkoff, Ekaterina Tkatchouk
Publikováno v:
Journal of Biomedical Materials Research Part B: Applied Biomaterials. 104:411-421
Accelerated in vitro biostability studies are useful for making relativistic comparisons between materials. However, no in vitro study can completely replicate the complex biochemical and biomechanical environment that a material experiences in the h
Autor:
Ajay Padsalgikar
Plastics in Medical Devices for Cardiovascular Applications enables designers of new cardiovascular medical devices to make decisions about the kind of plastics that can go into the manufacture of their device by explaining the property requirements
Autor:
Elizabeth Cosgriff-Hernandez, Tyler Touchet, Lisa Mellin, Anna Norlin-Weissenrieder, James Runt, Genevieve Gallagher, Ajay Padsalgikar, Ciprian Iacob
Publikováno v:
Journal of Biomedical Materials Research Part B: Applied Biomaterials. 103:159-168
Polyurethane biostability has been the subject of intense research since the failure of polyether polyurethane pacemaker leads in the 1980s. Accelerated in vitro testing has been used to isolate degradation mechanisms and predict clinical performance
Publikováno v:
Journal of Polymer Science Part B: Polymer Physics. 49:865-872
A novel macrodiol based on mixed silicone and car- bonate chemistries was synthesized and used as a soft segment precursor in the synthesis of two series of segmented polyur- ethane (PU) copolymers varying in hard segment content and soft segment mol
Publikováno v:
Polymer. 51:4375-4382
Segmented polyurethane (PU) block copolymers were synthesized using 4,4′-methylenediphenyl diisocyanate and 1,4-butanediol as hard segments and oligomeric ethoxypropyl polydimethylsiloxane (PDMS) as the soft segments, with hard segment contents ran
Autor:
James Runt, Ajay Padsalgikar, Rebeca Hernández, Suphannee Pongkitwitoon, Jadwiga Weksler, Taeyi Choi
Publikováno v:
Polymer. 50:6305-6311
In this paper we explore the temperature dependence of segregation of hard and soft segments of selected segmented polyurethane copolymers using synchrotron small-angle X-ray scattering (SAXS). The copolymers are composed of the same hard segments bu
Publikováno v:
Polymer. 50:2320-2327
Segmented polyurethane block copolymers were synthesized using 4,4′-methylenediphenyl diisocyanate (MDI) and 1,4-butanediol (BDO) as hard segments and various soft segments derived from poly(hexamethylene oxide) (PHMO) and poly(dimethylsiloxane) (P