Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Ajay M. Tammewar"'
1
Intraocular Properties of a Repository Urokinase Receptor Antagonist Å36 Peptide in Rabbits
Autor: Erin C. Barron, Terence R. Jones, William R. Freeman, Ajay M. Tammewar, Bruce Babson, Lingyun Cheng, I. Falkenstein, Igor Kozak
Publikováno v: Current Eye Research. 35:742-750
To evaluate the intraocular properties of A36, a peptide that directly antagonizes the cell surface urokinase receptor and so prevents pericellular urokinase plasminogen activator activity.A total of 41 rabbits were used. The toxicity study tested th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74bfdf643328b3933e3a0809e6c7d760
https://doi.org/10.3109/02713683.2010.486519
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2
Toxicity and Intraocular Properties of a Novel Long-Acting Anti-Proliferative and Anti-Angiogenic Compound IMS2186
Autor: Qi-Xiang Li, Dehua Yu, Gabriel A. Silva, Flossie Wong-Staal, Ning Ke, Guohong Liu, William R. Freeman, I. Falkenstein, Michelle Hysell, James E. Macdonald, Erin C. Barron, Ajay M. Tammewar, Lingyun Cheng
Publikováno v: Current Eye Research. 33:599-609
To investigate the intraocular properties and toxicity of IMS2186, a small molecule developed as an anti-choroidal neovascularization (anti-CNV) drug.Cellular toxicity and mechanism of action was tested on cell lines in vitro. Intraocular studies use
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99b2b887bbb9b0726e647ac3e5e41fb6
https://doi.org/10.1080/02713680802226582
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3
Intraocular Properties of An Alkoxyalkyl Derivative of Cyclic 9-(S)-(3-Hydroxyl-2-Phosphonomehoxypropyl) Adenine, An Intravitreally Injectable Anti-HCMV Drug in Rabbit and Guinea Pig
Autor: Erin C. Barron, Karl Y. Hostetler, I. Falkenstein, William R. Freeman, Ajay M. Tammewar, Lingyun Cheng, Igor Kozak, James R. Beadle
Publikováno v: Journal of Ocular Pharmacology and Therapeutics. 23:433-444
The aim of this study was to investigate intraocular properties and determine the highest nontoxic dose of hexadecyloxypropyl-cyclic-HPMPA (HDP-cHPMPA), a novel, potent, intravitreally injectable, slow-releasing crystalline drug for long-acting treat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a611281631feebc68ce271f24c6e0c94
https://doi.org/10.1089/jop.2007.0018
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4
STANDARDIZED VISUAL ACUITY RESULTS ASSOCIATED WITH PRIMARY VERSUS SECONDARY BEVACIZUMAB (AVASTIN) TREATMENT FOR CHOROIDAL NEOVASCULARIZATION IN AGE-RELATED MACULAR DEGENERATION
Autor: Ajay M. Tammewar, William R. Freeman, Igor Kozak, I. Falkenstein, Lingyun Cheng, V.L. Morrison
Publikováno v: Retina. 27:701-706
We agree with them thatstandardized visual acuity measurements with Early Treatment Diabetic Retinopathy Studycharts are important in evaluating any vision changes after treatment. This is particularly truein the low-vision range of patients with age
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f938e1f71bea180f795df852258c95d7
https://doi.org/10.1097/iae.0b013e3180654240
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5
Intraocular pharmacokinetics of a crystalline lipid prodrug, octadecyloxyethyl-cyclic-cidofovir, for cytomegalovirus retinitis
Autor: William R. Freeman, James R. Beadle, Carl K. Hoh, Karl Y. Hostetler, Ajay M. Tammewar, Lingyun Cheng
Publikováno v: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics. 27(2)
To evaluate the intraocular pharmacokinetics of octadecyloxyethyl-cyclic-cidofovir (ODE-cCDV) after intravitreal injection into rabbit eyes.Twenty-seven New Zealand red rabbits (27 eyes) received intravitreal injections of (14)C-labeled ODE-cCDV (100
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccc6ab414e3b4a50d80a17b98897a184
https://pubmed.ncbi.nlm.nih.gov/21351867
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6
Intravitreal crystalline drug delivery for intraocular proliferation diseases
Autor: Ajay M. Tammewar, James R. Beadle, Lingyun Cheng, William R. Freeman, Dirk-Uwe Bartsch, I. Falkenstein, Nadya Valiaeva, Kathy A. Aldern, Karl Y. Hostetler
Publikováno v: Investigative ophthalmologyvisual science. 51(1)
Direct delivery of drug to the posterior segment by intravitreal injection or intravitreal implant has demonstrated advantages in treating acute or chronic vitreoretinal diseases. Contrasted with systemic drug administration, local intravitreal drug
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba471e747e4d62aa79704e9b65a782e5
https://pubmed.ncbi.nlm.nih.gov/19696179
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7
Imaging vitreomacular interface abnormalities in the coronal plane by simultaneous combined scanning laser and optical coherence tomography
Autor: Igor Kozak, Richard B Rosen, William R. Freeman, Dirk-Uwe Bartsch, Patricia Garcia, Ajay M. Tammewar, I. Falkenstein
Publikováno v: The British journal of ophthalmology. 93(3)
Aim: To describe vitreoretinal imaging of eyes with vitreomacular abnormalities using high-resolution coronal-plane optical coherence tomography (OCT) scanning combined with simultaneous scanning laser ophthalmoscope (SLO) imaging. Methods: A SLO–O
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85365e06180e8e3becb7aa723d8a3b28
https://pubmed.ncbi.nlm.nih.gov/19019945
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8
Comparison of 4 mg versus 20 mg intravitreal triamcinolone acetonide injections
Autor: Ajay M. Tammewar, William R. Freeman, I. Falkenstein, Igor Kozak, Ozcan Kayikcioglu, Lingyun Cheng, Michael H. Goldbaum
Aims: To compare the non-decanted (standard) 4 mg versus the decanted 20 mg intravitreal triamcinolone acetonide (IVTA) injections and to assess their effect on intraocular pressure (IOP). Methods: We retrospectively reviewed the records of 92 consec
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4bd59a2cd9c107eabefb10159577a9b
https://europepmc.org/articles/PMC2776725/
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9
Intravitreal properties of porous silicon photonic crystals: a potential self-reporting intraocular drug-delivery vehicle
Autor: Ajay M. Tammewar, William R. Freeman, Dokyoung Kim, L. Cheng, Michael J. Sailor, I. Falkenstein, Frédérique Cunin, Emily Anglin
Publikováno v: British Journal of Ophthalmology
British Journal of Ophthalmology, BMJ Publishing Group, 2008, 92 (5), pp.705-711. ⟨10.1136/bjo.2007.133587⟩
National audience; Aim: To determine the suitability of porous silicon photonic crystals for intraocular drug-delivery. Methods: A rugate structure was electrochemically etched into a highly doped p-type silicon substrate to create a porous silicon f
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1baef1020f817f5fb79f882035d50319
https://hal.archives-ouvertes.fr/hal-00276656
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10
Evaluation of subretinal triamcinolone acetonide in patients with exudative age-related macular degeneration
Autor: Ajay M. Tammewar, William R. Freeman, Lingyun Cheng, I. Falkenstein, Igor Kozak
Publikováno v: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics. 23(1)
The aim of this paper was to present the results of subretinal delivery of triamcinolone acetonide (TCA) in humans with choroidal neovascularization (CNV) caused by age-related macular degeneration (AMD).Twenty two (22) eyes of 22 patients underwent
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fc1a075bd888ff1e3c0fba77aa681e9
https://pubmed.ncbi.nlm.nih.gov/17341150
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