Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ajay Kesharwani"'
Autor:
Larissa Jank, Ajay Kesharwani, Taekyung Ryu, Deepika Joshi, Dimitrios C. Ladakis, Matthew D. Smith, Saumitra Singh, Tanina Arab, Kenneth W. Witwer, Peter A. Calabresi, Chan-Hyun Na, Pavan Bhargava
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-17 (2024)
Abstract Extracellular vesicles (EVs) are released by all cells, can cross the blood–brain barrier, and have been shown to play an important role in cellular communication, substance shuttling, and immune modulation. In recent years EVs have shifte
Externí odkaz:
https://doaj.org/article/58832157349e4b658d1e863b8fc976b1
Autor:
Kanak Gupta, Ajay Kesharwani, Steven Rua, Saumitra Sen Singh, Catherine Siu, Larissa Jank, Matthew D. Smith, Peter A. Calabresi, Pavan Bhargava
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-13 (2023)
Abstract Multiple sclerosis (MS) has traditionally been viewed as a chronic inflammatory disease affecting the white matter of the central nervous system. However, over the past two decades, increasing evidence has highlighted the role of gray matter
Externí odkaz:
https://doaj.org/article/b4a04aa67a6049cabf791e0de66ecb51
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 19, p 10789 (2021)
Multiple sclerosis (MS) is an inflammatory disease of the central nervous system that finally leads to demyelination. Demyelinating optic neuritis is a frequent symptom in MS. Recent studies also revealed synapse dysfunctions in MS patients and MS mo
Externí odkaz:
https://doaj.org/article/98f40fdb89ee43bba7e20a5f8a5fcdef
Autor:
Mayur Dembla, Ajay Kesharwani, Sivaraman Natarajan, Claudia Fecher‐Trost, Richard Fairless, Sarah K Williams, Veit Flockerzi, Ricarda Diem, Karin Schwarz, Frank Schmitz
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 11, Pp n/a-n/a (2018)
Abstract Optic neuritis is one of the first manifestations of multiple sclerosis. Its pathogenesis is incompletely understood, but considered to be initiated by an auto‐immune response directed against myelin sheaths of the optic nerve. Here, we de
Externí odkaz:
https://doaj.org/article/7372cd2bdb174bcbac029be8963c4d0f
Autor:
Nripendra Nath Mishra, Ajay Kesharwani, Aakanksha Agarwal, Suja Kizhiyedath Polachira, Reshmi Nair, Satish Kumar Gupta
Publikováno v:
Viruses, Vol 10, Iss 11, p 580 (2018)
Herpes simplex virus-2 (HSV-2) infection is the most common cause of genital ulcers. The impact of ulcers also demonstrates a strong link to the human immunodeficiency virus (HIV) infection. Complications, drug resistance, and side-effects of anti-vi
Externí odkaz:
https://doaj.org/article/536ae0a89e544d13829aa6d0c98b1d71
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 19
International Journal of Molecular Sciences, Vol 22, Iss 10789, p 10789 (2021)
Volume 22
Issue 19
International Journal of Molecular Sciences, Vol 22, Iss 10789, p 10789 (2021)
Multiple sclerosis (MS) is an inflammatory disease of the central nervous system that finally leads to demyelination. Demyelinating optic neuritis is a frequent symptom in MS. Recent studies also revealed synapse dysfunctions in MS patients and MS mo
Autor:
Reshmi Nair, Ajay Kesharwani, Aakanksha Agarwal, Satish K. Gupta, Suja Kizhiyedath Polachira, Nripendra N. Mishra
Publikováno v:
Viruses, Vol 10, Iss 11, p 580 (2018)
Viruses
Volume 10
Issue 11
Viruses
Volume 10
Issue 11
Herpes simplex virus-2 (HSV-2) infection is the most common cause of genital ulcers. The impact of ulcers also demonstrates a strong link to the human immunodeficiency virus (HIV) infection. Complications, drug resistance, and side-effects of anti-vi
Autor:
Aakanksha Agarwal, Satish K. Gupta, Suja Kizhiyedath Polachira, Ajay Kesharwani, Reshmi Nair, Nripendra N. Mishra
Publikováno v:
BMC Complementary and Alternative Medicine
Background Development of new and effective therapeutics for sexually transmitted herpes simplex virus-2 (HSV-2) infection is important from public health perspective. With an aim to identify natural products from medicinal plants, in the present stu
Autor:
Aakanksha Agarwal, Satish K. Gupta, Ajay Kesharwani, Prachi Kumar, Utsab Debnath, Seturam B. Katti
Publikováno v:
Chemical biologydrug design. 90(4)
An in silico method has been used to discover N-hydroxy-substituted 2-aryl acetamide analogs as a new class of HIV-1 integrase inhibitors. Based on the molecular requirements of the binding pocket of catalytic active site, two molecules (compounds 2