Zobrazeno 1 - 10
of 425
pro vyhledávání: '"Ajay K. Gopal"'
Autor:
Mazyar Shadman, Kwang W. Ahn, Manmeet Kaur, Lazaros Lekakis, Amer Beitinjaneh, Madiha Iqbal, Nausheen Ahmed, Brian Hill, Nasheed M. Hossain, Peter Riedell, Ajay K. Gopal, Natalie Grover, Matthew Frigault, Jonathan Brammer, Nilanjan Ghosh, Reid Merryman, Aleksandr Lazaryan, Ron Ram, Mark Hertzberg, Bipin Savani, Farrukh Awan, Farhad Khimani, Sairah Ahmed, Vaishalee P. Kenkre, Matthew Ulrickson, Nirav Shah, Mohamed A. Kharfan-Dabaja, Alex Herrera, Craig Sauter, Mehdi Hamadani
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract In patients with relapsed DLBCL in complete remission (CR), autologous hematopoietic cell transplantation (auto-HCT) and CAR-T therapy are both effective, but it is unknown which modality provides superior outcomes. We compared the efficacy
Externí odkaz:
https://doaj.org/article/e8520ed8a9ea4ad4a6eebc0252da84a4
Autor:
Jeffrey R. Whiteaker, Lei Zhao, Regine M. Schoenherr, Dongqing Huang, Rachel A. Lundeen, Ulianna Voytovich, Jacob J. Kennedy, Richard G. Ivey, Chenwei Lin, Oscar D. Murillo, Travis D. Lorentzen, Simona Colantonio, Tessa W. Caceres, Rhonda R. Roberts, Joseph G. Knotts, Joshua J. Reading, Candice D. Perry, Christopher W. Richardson, Sandra S. Garcia-Buntley, William Bocik, Stephen M. Hewitt, Shrabanti Chowdhury, Jackie Vandermeer, Stephen D. Smith, Ajay K. Gopal, Nirasha Ramchurren, Steven P. Fling, Pei Wang, Amanda G. Paulovich
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionImmunotherapy is an effective treatment for a subset of cancer patients, and expanding the benefits of immunotherapy to all cancer patients will require predictive biomarkers of response and immune-related adverse events (irAEs). To suppo
Externí odkaz:
https://doaj.org/article/f412d3d737e448d4a0f5abc24df6f60b
Autor:
Sriram Balasubramanian, Brendan Hodkinson, Stephen J. Schuster, Nathan H. Fowler, Judith Trotman, Georg Hess, Bruce D. Cheson, Michael Schaffer, Steven Sun, Sanjay Deshpande, Jessica Vermeulen, Gilles Salles, Ajay K. Gopal
Publikováno v:
Cancer Medicine, Vol 11, Iss 1, Pp 61-73 (2022)
Abstract Background The single‐arm DAWN trial (NCT01779791) of ibrutinib monotherapy in patients with relapsed/refractory follicular lymphoma (FL) showed an overall response rate (ORR) of 20.9% and a median response duration of 19.4 months. This bi
Externí odkaz:
https://doaj.org/article/8e668f1ebce046fb90165c45e83463d9
Autor:
David S. Hong, Ajay K. Gopal, Alexander N. Shoushtari, Sandip P. Patel, Aiwu R. He, Toshihiko Doi, Suresh S. Ramalingam, Amita Patnaik, Shahneen Sandhu, Ying Chen, Craig B. Davis, Timothy S. Fisher, Bo Huang, Kolette D. Fly, Antoni Ribas
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Section HeadClinical/translational cancer immunotherapyBackgroundThe goal of this study was to estimate the objective response rate for utomilumab in adults with immune checkpoint inhibitor (ICI)-refractory melanoma and non–small-cell lung cancer (
Externí odkaz:
https://doaj.org/article/a396b9eb0e0b40ccbf67fc789b9b7881
Autor:
Ryan C. Lynch, Stefan Alig, Chaitra S. Ujjani, Christina Poh, Edus H. Warren, Stephen D. Smith, Mazyar Shadman, Andrei Shustov, Brian Till, Vikram M. Raghunathan, Yolanda Tseng, Hilary Coye, Megan Shelby, Susan Ottemiller, Sarith Keo, Kaitlin Verni, Hongyan Du, Jackie Vandermeer, Ashley Gaston, Heather Rasmussen, Avanti Gulhane, Delphine L. Chen, Paul Martin, Edmond Marzbani, Jenna Voutsinas, Ash A. Alizadeh, Ajay K. Gopal
Publikováno v:
HemaSphere, Vol 6, Pp 26-27 (2022)
Externí odkaz:
https://doaj.org/article/1dca62dfced740de83e0d17bd541a259
Autor:
Mazyar Shadman, Jordan Gauthier, Kevin A. Hay, Jenna M. Voutsinas, Filippo Milano, Ang Li, Alexandre V. Hirayama, Mohamed L. Sorror, Sindhu Cherian, Xueyan Chen, Ryan D. Cassaday, Brian G. Till, Ajay K. Gopal, Brenda M. Sandmaier, David G. Maloney, Cameron J. Turtle
Publikováno v:
Blood Advances, Vol 3, Iss 20, Pp 3062-3069 (2019)
Abstract: Allogeneic hematopoietic cell transplantation (allo-HCT) is offered to selected patients after chimeric antigen receptor–modified T-cell (CAR-T) therapy. Lymphodepleting chemotherapy and CAR-T therapy have immunosuppressive and immunomodu
Externí odkaz:
https://doaj.org/article/377350884943460f8682f0b6563104d6
Autor:
Phuong Vo, Ted A. Gooley, Joseph G. Rajendran, Darrell R. Fisher, Johnnie J. Orozco, Damian J. Green, Ajay K. Gopal, Robyn Haaf, Margaret Nartea, Rainer Storb, Frederick R. Appelbaum, Oliver W. Press, John M. Pagel, Brenda M. Sandmaier
Publikováno v:
Haematologica, Vol 105, Iss 6 (2020)
Outcomes of patients with persistent high-risk leukemia or myelodysplasia prior to allogeneic hematopoietic cell transplantation are dismal. We therefore conducted a phase I trial evaluating the use of CD45-targeted radiotherapy preceding hematopoiet
Externí odkaz:
https://doaj.org/article/5305b45938ed4d9fbd2343bde3761ae8
Publikováno v:
HemaSphere, Vol 4, Iss 1, p e317 (2020)
Abstract. The overall prognosis of patients with follicular lymphoma has substantially improved over the last decades with a 10-year overall survival of around 80% for the majority of patients. However, for most patients follicular lymphoma it is sti
Externí odkaz:
https://doaj.org/article/ecb51e2187cd4511b4f535431ea7aa92
Autor:
Ang Li, Chris Davis, Qian Wu, Shan Li, Madeline F. Kesten, Leona A. Holmberg, Ajay K. Gopal, David A. Garcia
Publikováno v:
Blood Advances, Vol 1, Iss 12, Pp 707-714 (2017)
Abstract: Management of venous thromboembolism (VTE) remains challenging in patients with hematologic malignancy who undergo hematopoietic cell transplantation (HCT) due to prolonged thrombocytopenia. This study aims to (1) determine the incidence of
Externí odkaz:
https://doaj.org/article/6cf3209b47cb49599d18a423ada4b4d3
Autor:
Gilles Salles, Stephen J. Schuster, Sven de Vos, Nina D. Wagner-Johnston, Andreas Viardot, Kristie A. Blum, Christopher R. Flowers, Wojciech J. Jurczak, Ian W. Flinn, Brad S. Kahl, Peter Martin, Yeonhee Kim, Sanatan Shreay, Matthias Will, Bess Sorensen, Madlaina Breuleux, Pier Luigi Zinzani, Ajay K. Gopal
Publikováno v:
Haematologica, Vol 102, Iss 4 (2017)
Externí odkaz:
https://doaj.org/article/659c521f054746b8aea3c4d816e10163