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pro vyhledávání: '"Ajay K. Banerjee"'
Publikováno v:
Cardiovascular Pharmacology of 5-Hydroxytryptamine ISBN: 9789401067010
Ketanserin lowers arterial blood pressure in both animals and humans, but the mechanism of its antihypertensive action is in debate [see 1]. In general, it is now accepted that ketanserin, at least partly, lowers blood pressure by α 1-adrenoceptor b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76d697c0c57aa09830c29d5bfda08861
https://doi.org/10.1007/978-94-009-0479-8_30
https://doi.org/10.1007/978-94-009-0479-8_30
Publikováno v:
European Journal of Pharmacology. 145:67-73
The mechanism of the increase in heart rate caused by 5-hydroxytryptamine (5-HT) in the spinal guinea-pig was investigated. Administration of 5-HT (15, 30, 60 and 120 micrograms.kg-1 i.v.) elicited dose dependent increases in heart rate. The response
Publikováno v:
European Journal of Pharmacology. 168:257-260
Intrathecal administration of ketanserin and phentolamine elicited dose-dependent falls in arterial blood pressure and heart rate in anaesthetized rats without attenuation of the pressor responses to i.v. injections of phenylephrine. It is concluded