Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Ajanthy Arulpragasam"'
Autor:
Ajanthy Arulpragasam, Bryan K. Ward, Thomas Ratajczak, Sarah L. Rea, Peter J. Fuller, Carmel Cluning
Publikováno v:
Molecular Endocrinology. 27:1020-1035
The heat-shock protein 90 (Hsp90) cochaperone FK506-binding protein 52 (FKBP52) upregulates, whereas FKBP51 inhibits, hormone binding and nuclear targeting of the glucocorticoid receptor (GR). Decreased cortisol sensitivity in the guinea pig is attri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be9a389fcb3abf885d77c27be1c3eb9c
https://doi.org/10.1210/me.2012-1023
https://doi.org/10.1210/me.2012-1023
Autor:
Thomas Ratajczak, Ajanthy Arulpragasam, Arthur D. Conigrave, Bernadette Pedersen, Suzanne J. Brown, Bryan K. Ward, Aaron L. Magno, Shelby Mullin, Sarah L. Rea, Evan Ingley
Publikováno v:
Journal of cellular physiology. 233(1)
The mechanisms responsible for the processing and quality control of the calcium-sensing receptor (CaSR) in the endoplasmic reticulum (ER) are largely unknown. In a yeast two-hybrid screen of the CaSR C-terminal tail (residues 865-1078), we identifie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d28fe0b063f2bd674e3eced34c5e168
https://pubmed.ncbi.nlm.nih.gov/28419469
https://pubmed.ncbi.nlm.nih.gov/28419469
Autor:
Aaron L. Magno, Suzanne J. Brown, Evan Ingley, Bryan K. Ward, Thomas Ratajczak, Arthur D. Conigrave, Ajanthy Arulpragasam
Publikováno v:
Biochemical Journal. 441:995-1007
A yeast two-hybrid screen performed to identify binding partners of the CaR (calcium-sensing receptor) intracellular tail identified the adaptor protein 14-3-3θ as a novel binding partner that bound to the proximal membrane region important for CaR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0579075456dc35d93be5d3427edc420
https://doi.org/10.1042/bj20111277
https://doi.org/10.1042/bj20111277
Autor:
Giles W. Plant, Alan R. Harvey, Elske H. P. Franssen, Takako Sasaki, Marc J. Ruitenberg, Samantha J. Busfield, Jana Vukovic, Joost Verhaagen, Ajanthy Arulpragasam, Kasper C. D. Roet
Publikováno v:
GLIA, 57, 424-443. John Wiley and Sons Inc.
The primary olfactory pathway in adult mammals has retained a remarkable potential for self-repair. A specialized glial cell within the olfactory nerve, called olfactory ensheathing cell (OEC), and their associated extracellular matrix are thought to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afad4578631527c8969a8f1789c297cc
https://doi.org/10.1002/glia.20771
https://doi.org/10.1002/glia.20771
Publikováno v:
Experimental Neurology. 207:314-328
When grafted onto the cut optic nerve, chimeric peripheral nerve (PN) sheaths reconstituted with adult Schwann cells (SCs) support the regeneration of adult rat retinal ganglion cell (RGC) axons. Regrowth can be further enhanced by using PN containin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fc843f69ee5decf08415f3366585aa7
https://doi.org/10.1016/j.expneurol.2007.07.001
https://doi.org/10.1016/j.expneurol.2007.07.001
Autor:
Gary W Plant, S. Hisheh, Joost Verhaagen, Alan R. Harvey, Ajanthy Arulpragasam, Sarah G Leaver, Qi Cui
Publikováno v:
Gene Therapy, 13(18), 1328-41. Nature Publishing Group
We compared the effects of intravitreal injection of bi-cistronic adeno-associated viral (AAV-2) vectors encoding enhanced green fluorescent protein (GFP) and either ciliary neurotrophic factor (CNTF), brain-derived neurotrophic factor (BDNF) or grow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86afa98ddf611eebd2c9b68d422c7639
https://doi.org/10.1038/sj.gt.3302791
https://doi.org/10.1038/sj.gt.3302791
Publikováno v:
International Journal of Cancer. 118:509-512
N1, N11-diethylnorspermine (DENSPM) is a polyamine analog that is currently under investigation as a novel anticancer drug. Although it has shown promising preclinical activity, there has been large variation in responsiveness reported between differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8535c3d71442f7c9ed2373850676b313
https://doi.org/10.1002/ijc.21359
https://doi.org/10.1002/ijc.21359
Publikováno v:
Journal of Biological Chemistry. 279:22131-22137
Many drugs and chemicals found in the environment are either detoxified by N-acetyltransferase 1 (NAT1, EC 2.3.1.5) and eliminated from the body or bioactivated to metabolites that have the potential to cause toxicity and/or cancer. NAT1 activity in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::211b9c79c9f05c14245614d7d9ca12b4
https://doi.org/10.1074/jbc.m312858200
https://doi.org/10.1074/jbc.m312858200
Publikováno v:
The Journal of biological chemistry. 279(21)
Many drugs and chemicals found in the environment are either detoxified by N-acetyltransferase 1 (NAT1, EC 2.3.1.5) and eliminated from the body or bioactivated to metabolites that have the potential to cause toxicity and/or cancer. NAT1 activity in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::430782117c5dbb14963f510f7941b52d
https://pubmed.ncbi.nlm.nih.gov/15039438
https://pubmed.ncbi.nlm.nih.gov/15039438
Human N-acetyltransferase Type I (NAT1) catalyses the acetylation of many aromatic amine and hydrazine compounds and it has been implicated in the catabolism of folic acid. The enzyme is widely expressed in the body, although there are considerable d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d5416b1a9d96e7ebc56b0fa2f99cfb4
https://europepmc.org/articles/PMC1223780/
https://europepmc.org/articles/PMC1223780/
