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Autor:
Jonathan L. Kaufman, Jeffrey A. Zonder, Sandy W. Wong, Philip H. Imus, Zachary Walker, Andrew Dorr, Jill Abbey, Ajai Imus, Marc Nasoff, Bin Liu, Mark A. Schroeder, Tomer M Mark, Thomas Martin, Daniel W. Sherbenou
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 21:S164
Background Cluster of differentiation 46 (CD46) is highly expressed in multiple myeloma, especially in patients (pts) with gain of chromosome 1q and in the refractory setting. In vitro studies show upregulation and enhanced cytotoxicity upon treatmen