Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Ajai A, Dandekar"'
Autor:
Yu-Ying Phoebe Hsieh, Wanting Sun, Janet M Young, Robin Cheung, Deborah A Hogan, Ajai A Dandekar, Harmit S Malik
Publikováno v:
PLoS Biology, Vol 22, Iss 6, p e3002694 (2024)
Fungi and bacteria coexist in many polymicrobial communities, yet the molecular basis of their interactions remains poorly understood. Here, we show that the fungus Candida albicans sequesters essential magnesium ions from the bacterium Pseudomonas a
Externí odkaz:
https://doaj.org/article/2a21b5d9164a439aa58deebd1547c39b
Autor:
Lucia Grassi, Kyle L. Asfahl, Sara Van den Bossche, Ine Maenhout, Andrea Sass, Yannick Vande Weygaerde, Eva Van Braeckel, Bruno Verhasselt, Jerina Boelens, Michael M. Tunney, Ajai A. Dandekar, Tom Coenye, Aurélie Crabbé
Publikováno v:
Biofilm, Vol 7, Iss , Pp 100206- (2024)
It is increasingly recognized that interspecies interactions may modulate the pathogenicity of Pseudomonas aeruginosa during chronic lung infections. Nevertheless, while the interaction between P. aeruginosa and pathogenic microorganisms co-infecting
Externí odkaz:
https://doaj.org/article/18ff7c56d8d0412ab009cf7aca01cbfc
Publikováno v:
PLoS Pathogens, Vol 20, Iss 3, p e1012078 (2024)
XRE-cupin family proteins containing an DNA-binding domain and a cupin signal-sensing domain are widely distributed in bacteria. In Pseudomonas aeruginosa, XRE-cupin transcription factors have long been recognized as regulators exclusively controllin
Externí odkaz:
https://doaj.org/article/ed47e7fd85a54b2cae6a6b54b6b76679
Autor:
Mylène C. Trottier, Thays de Oliveira Pereira, Marie-Christine Groleau, Lucas R. Hoffman, Ajai A. Dandekar, Eric Déziel
Publikováno v:
mBio, Vol 15, Iss 3 (2024)
ABSTRACT Pseudomonas aeruginosa, a bacterium causing infections in immunocompromised individuals, regulates several of its virulence functions using three interlinked quorum sensing (QS) systems (las, rhl, and pqs). Despite its presumed importance in
Externí odkaz:
https://doaj.org/article/6edfb6c216cc4837b0609d1cfccc41f6
Autor:
Caleb M Schwartzkopf, Autumn J Robinson, Mary Ellenbecker, Dominick R Faith, Amelia K Schmidt, Diane M Brooks, Lincoln Lewerke, Ekaterina Voronina, Ajai A Dandekar, Patrick R Secor
Publikováno v:
PLoS Pathogens, Vol 19, Iss 2, p e1010925 (2023)
The opportunistic pathogen Pseudomonas aeruginosa PAO1 is infected by the filamentous bacteriophage Pf4. Pf4 virions promote biofilm formation, protect bacteria from antibiotics, and modulate animal immune responses in ways that promote infection. Fu
Externí odkaz:
https://doaj.org/article/e25d2e5c1a504c2b804c4ab1f43c9be5
Publikováno v:
mSystems, Vol 7, Iss 2 (2022)
ABSTRACT In people with the genetic disease cystic fibrosis (CF), bacterial infections involving the opportunistic pathogen Pseudomonas aeruginosa are a significant cause of morbidity and mortality. P. aeruginosa uses a cell-cell signaling mechanism
Externí odkaz:
https://doaj.org/article/8db2b8db0d794b4cbb150a45e875a386
Autor:
Nicole E. Smalley, Amy L. Schaefer, Kyle L. Asfahl, Crystal Perez, E. Peter Greenberg, Ajai A. Dandekar
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT In the opportunistic pathogenic bacterium Pseudomonas aeruginosa acyl-homoserine lactone quorum sensing (QS) can activate expression of dozens to hundreds of genes depending on the strain under investigation. Many QS-activated genes code for
Externí odkaz:
https://doaj.org/article/2ef094612d40466bbbff246cb11f0fb7
Publikováno v:
Environment International, Vol 156, Iss , Pp 106619- (2021)
The rapid increase of antibiotic resistance is a serious challenge around the world. Antibiotics are present in various environments at sub-lethal concentrations, but how resistance emerges under sub-lethal conditions is not fully clear. In this stud
Externí odkaz:
https://doaj.org/article/21ba34cd212e43a49f32bb3a28a9b545
Autor:
Huicong Yan, Kyle L. Asfahl, Na Li, Feng Sun, Junwei Xiao, Dongsheng Shen, Ajai A. Dandekar, Meizhen Wang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-7 (2019)
Quorum sensing (QS) regulates production of ‘public goods’ by Pseudomonas aeruginosa, which releases toxic hydrogen cyanide to constrain QS-deficient cheaters. Here, Yan et al. show that QS-proficient strains protect themselves by producing a cya
Externí odkaz:
https://doaj.org/article/80dcc52ef5834a37a2953282e4ece776
Autor:
Renae L. Cruz, Kyle L. Asfahl, Sara Van den Bossche, Tom Coenye, Aurélie Crabbé, Ajai A. Dandekar
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT The opportunistic pathogen Pseudomonas aeruginosa is a leading cause of airway infection in cystic fibrosis (CF) patients. P. aeruginosa employs several hierarchically arranged and interconnected quorum sensing (QS) regulatory circuits to pr
Externí odkaz:
https://doaj.org/article/3cfd45f3bc1647b5bc6bf4112cef5bcb