Zobrazeno 1 - 10 of 674 pro vyhledávání: '"Aj, Sinclair"'
1
Blunted nutrient-response pathways in adipose tissue following high fat meals in men with metabolic syndrome: A randomized postprandial transcriptomic study
Autor: AL Dordevic, SL Coort, CT Evelo, C Murgia, AJ Sinclair, MP Bonham, Larsen, Amy, P Gran, D Cameron-Smith
Background: Excessive adipose tissue is central to disease burden posed by the Metabolic Syndrome (MetS). Whilst much is known of the altered transcriptomic regulation of adipose tissue under fasting conditions, little is known of the responses to hi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c33bfa484e648e3c4a392feeb3c67479
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4
Cerebrovascular disease and oxidative stress
Autor: SE Gariballa, AJ Sinclair
Publikováno v: Reviews in Clinical Gerontology. 9:197-206
There is strong indirect evidence that free radical production appears to be an important mechanism of brain injury after exposure to ischaemia and reperfusion. Although significant brain damage occurs during an ischaemic episode, new cerebral damage
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a0d441782ecf79e2edf14d138446ac2b
https://doi.org/10.1017/s0959259899009314
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5
Diagnosing undernutrition in elderly people
Autor: AJ Sinclair, SE Gariballa
Publikováno v: Reviews in Clinical Gerontology. 7:367-371
One of the greatest challenges of medicine in old age is for physicians to understand the process of aging and to be able to distinguish it from disease, lifestyle factors and environmental exposures whose cumulative effects account for many of the c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eeda29a33e16fe1e455344e67f6673af
https://doi.org/10.1017/s0959259897074108
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7
Objective assessment of morbidity and disability in aged diabetic patients
Autor: C Jenkins, AJ Sinclair, AJ Bayer
Publikováno v: Practical Diabetes International. 12:24-26
We decided to study the impact of diabetes mellitus on morbidity and disability in the elderly. Three groups were studied: (1) 30 consecutively admitted diabetic in-patients; (2) 30 contemporary non-diabetic in-patients; (3) a community group of 30 n
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ae47487c973867ec6a913344f7682d73
https://doi.org/10.1002/pdi.1960120110
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8
Epstein-Barr virus exploits the normal cell pathway to regulate Rb activity during the immortalisation of primary B-cells
Autor: Ej, Cannell, Paul Farrell, Aj, Sinclair
Publikováno v: Europe PubMed Central
Infection of human primary B-lymphocytes with Epstein-Barr virus (EBV) drives quiescent cells into continual proliferation and results in the outgrowth of immortal cell lines. This requires re-programming of the mechanisms that, in the absence of app
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ca842f6b2621247147c63bab5d8f16a2
https://pubmed.ncbi.nlm.nih.gov/8875979
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9
Betaxolol and glucose-insulin relationships: studies in normal subjects taking glibenclamide or metformin
Autor: AJ Sinclair, IB Davies, SJ Warrington
Publikováno v: British journal of clinical pharmacology. 30(5)
1. The potential interaction between selective beta 1-adrenoceptor blockers and sulphonylureas or biguanides was studied by comparing the beta 1-adrenoceptor antagonist betaxolol with placebo in 12 normal subjects taking glibenclamide or metformin in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::936f5869ac70460370630b8eb9ff3508
https://pubmed.ncbi.nlm.nih.gov/2125460
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