Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Aizhen, Xiong"'
Publikováno v:
EBioMedicine, Vol 83, Iss , Pp 104239- (2022)
Summary: Background: Glioblastoma (GBM) is the most aggressive type of primary brain tumor and is often resistant to current therapies. Tumor microenvironment-centered therapies may unleash new hope for GBM treatment. Therefore, an in-depth understan
Externí odkaz:
https://doaj.org/article/69293055aaba40a39899929b005c3339
Publikováno v:
Liver Research, Vol 3, Iss 3, Pp 176-184 (2019)
Pyrrolizidine alkaloids (PAs) are among the most hepatotoxic natural compounds that are widely distributed throughout the world. Most PAs are metabolically activated to trigger toxicity. Exposure to herbal medicine containing PAs and food supplements
Externí odkaz:
https://doaj.org/article/f353a2f4d2d34b56b13f71bba6c703d7
Autor:
Xunjiang Wang, Wei Zhang, Yongfeng Yang, Yiran Chen, Yuzheng Zhuge, Aizhen Xiong, Li Yang, Zhengtao Wang
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background and Aims: The Gynura japonica-induced hepatic sinusoidal obstruction syndrome (HSOS) is closely related to pyrrolizidine alkaloids (PAs), and its prevalence has been increasing worldwide in recent years. However, no effective therapy for P
Externí odkaz:
https://doaj.org/article/5a5c99815714402e8937cdf971f5d9ca
Autor:
Xiao Yang, Hua Wang, Hong-Min Ni, Aizhen Xiong, Zhengtao Wang, Hiromi Sesaki, Wen-Xing Ding, Li Yang
Publikováno v:
Redox Biology, Vol 12, Iss , Pp 264-273 (2017)
Pyrrolizidine alkaloids (PAs) are a group of compounds found in various plants and some of them are widely consumed in the world as herbal medicines and food supplements. PAs are potent hepatotoxins that cause irreversible liver injury in animals and
Externí odkaz:
https://doaj.org/article/5407533afbf34de2bc91d2687b55a83f
Autor:
Hailuan Zeng, Renchao Tong, Wenxin Tong, Qiaoling Yang, Miaoyan Qiu, Aizhen Xiong, Siming Sun, Lili Ding, Hongli Zhang, Li Yang, Jingyan Tian
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract To investigate the metabolic biomarkers of predicting the transition from pre-diabetes (pre-DM) to normal glucose regulation (NGR) and diabetes (DM) in a longitudinal cohort study. 108 participants with pre-DM were followed up for ten years
Externí odkaz:
https://doaj.org/article/899ac24eba0b4a808497d872c0209f3c
Autor:
Xiaomeng Sun, Jiping Lan, Renchao Tong, Haoyue Zhang, Shuai Sun, Aizhen Xiong, Zhengtao Wang, Li Yang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 115, Iss , Pp - (2019)
Plantaginis semen, the dried mature seed of Plantago asiatica L. or Plantago deprdssa Willd., has a prominent effect on the treatment of obesity, type 2 diabetes and lipid disorders, however, its clinical application is limited due to inadequate in-d
Externí odkaz:
https://doaj.org/article/884d1db432c542e3b88ff60a0cd05fbf
Autor:
Lu Yan, Min Wei, Amy G. Gong, Pingping Song, Jianshu Lou, Cathy W. Bi, Sherry L. Xu, Aizhen Xiong, Tina T. Dong, Karl W. Tsim
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 5 (2017)
Kai-Xin-San (KXS), a Chinese herbal decoction, has been applied to medical care of depression for thousands of years. It is composed of two functional paired-herbs: Ginseng Radix et Rhizoma (GR)-Polygalae Radix (PR) and Acori Tatarinowii Rhizoma (ATR
Externí odkaz:
https://doaj.org/article/14bcabe3b78c4efe877712300750755c
Autor:
Yi Zhang, Kaiyuan Jiang, Pei Liu, Yingying Tang, Guancheng Li, Aizhen Xiong, Li Yang, Zhengtao Wang
Publikováno v:
Natural product research.
Protostane-type triterpenoids are antifibrotic nature components with unique structures in Alismatis Rhizoma. However, the underlying mechanisms of them against liver fibrosis are not well illustrated. The present study aims to study the targets and
Autor:
Yan Chen, Yingying Tang, Pei Liu, Jinyuan Wang, Weiqian Wang, Changhong Wang, Lili Ding, Aizhen Xiong, Li Yang, Zhengtao Wang
Publikováno v:
Chemico-Biological Interactions. 380:110505
Autor:
Changhong Wang, Aizhen Xiong, Li Yang, Fen Xiong, Weiqian Wang, Yan Chen, Gang Deng, Kaiyuan Jiang, Xuanling Ye, Zhengtao Wang
Publikováno v:
Toxicology Letters. 323:41-47
Gynura japonica (also named Tusanqi in Chinese) is used as a folk herbal medicine for treating blood stasis or traumatic injury. However, hundreds of hepatic sinusoidal obstruction syndrome (HSOS) cases have been reported after consumption of prepara