Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Aizhan Surumbayeva"'
Autor:
Aizhan Surumbayeva, Michael Kotliar, Linara Gabitova-Cornell, Andrey Kartashov, Suraj Peri, Nathan Salomonis, Artem Barski, Igor Astsaturov
Publikováno v:
STAR Protocols, Vol 2, Iss 4, Pp 100989- (2021)
Summary: Preparation of single-cell suspension from primary tumor tissue can provide a valuable resource for functional, genetic, proteomic, and tumor microenvironment studies. Here, we describe an effective protocol for mouse pancreatic tumor dissoc
Externí odkaz:
https://doaj.org/article/589e50c6390a4226890022c165a66ffb
Autor:
Charline Ogier, Alena Klochkova, Linara Gabitova-Cornell, Battuya Bayarmagnai, Diana Restifo, Aizhan Surumbayeva, Debora Barbosa Vendramini-Costa, Ralph Francescone, Janusz Franco-Barraza, Jaye Gardiner, Emmanuelle Nicolas, Andrei Efimov, Elizabeth A. Handorf, Kathy Q. Cai, Bojana Gligorijevic, Edna Cukierman, Igor Astsaturov
Publikováno v:
Cancer Research. 82:C047-C047
Pancreatic ductal adenocarcinoma (PDAC) cells derive their resistance to therapy and aggressive clinical course from the symbiotic signaling and metabolic interactions with cancer-associated fibroblasts (CAFs). Trogocytosis is a process of “nibblin
Autor:
Aizhan Surumbayeva, Riley Williams, Michael Kotliar, Maryclare Taylor, Débora B. Vendramini Costa, Charline Ogier, Diana Restifo, Kathy Q. Cai, Xueyang He, Paul Boutz, Siddharth Balachandran, Igor Astsaturov
Publikováno v:
Cancer Research. 82:B019-B019
Mortality from colon and pancreatic cancers arises from cancer metastatic dissemination to the liver. The glycemic load from carbohydrates (carbs) has been specifically linked to the risk of metastatic recurrence of stage 3 colorectal cancer, but the
Autor:
Charline Ogier, Alena Klochkova, Battuya Bayarmagnai, Linara Gabitova, Diana Restifo, Aizhan Surumbayeva, Janusz Franco-Barraza, Debora Vendramini Costa, Ralph Francescone, Jaye Gardiner, Emmanuelle Nicolas, Elizabeth A. Handorf, Kathy Q. Cai, Edna Cukierman, Igor Astsaturov
Publikováno v:
Cancer Research. 82:1571-1571
Pancreatic ductal adenocarcinoma (PDAC) cells derive their resistance to therapy and aggressive clinical course from the symbiotic signaling and metabolic interactions with cancer-associated fibroblasts (CAFs). CAFs have been shown to provide nutrien
Publikováno v:
Cancer Research. 82:2178-2178
High levels of dietary fats are associated with pancreatitis, diabetes, and pancreatic cancer. Sterol regulatory element binding protein Cleavage-Activating Protein (SCAP) is an essential intermediate in lipid-regulated activation of Sterol Regulator
Autor:
Artem Barski, Igor Astsaturov, Michael Kotliar, Kathy Q. Cai, Suraj Peri, Aizhan Surumbayeva, Linara Gabitova, Diana Restifo
Publikováno v:
Cancer Research. 81:PO-068
Gene expression analyses established at least two molecular subtypes of pancreatic adenocarcinoma (PDAC), the classical (or glandular), and the basal (or mesenchymal), each of which is associated with distinct prognoses and sensitivity to chemotherap
Autor:
Charline Ogier, Elizabeth Handorf, Jaye C. Gardiner, Diana Restifo, Ralph Francescone, Janusz Franco-Barraza, Linara Gabitova, Emmanuelle Nicolas, Kathy Q. Cai, Battuya Bayarmagnai, Alena Klochkova, Aizhan Surumbayeva, Igor Astsaturov, Débora Barbosa Vendramini-Costa, Edna Cukierman
Publikováno v:
Cancer Research. 81:PR-015
Pancreatic ductal adenocarcinoma (PDAC) cells derive their resistance to therapy and aggressive clinical course from the symbiotic signaling and metabolic interactions with cancer-associated fibroblasts (CAFs). CAFs have been shown to provide to meta
Autor:
Neelima Shah, Elizabeth Handorf, Rachel Chiaverelli, Vladimir Khazak, Aizhan Surumbayeva, Aaron R. Goldman, Suraj Peri, Carolyn Y. Fang, Kathy Q. Cai, Alana M. O’Reilly, Edna Cukierman, Emmanuelle Nicolas, Janusz Franco-Barraza, Diana Restifo, Nicole Weitz, Charline Ogier, Linara Gabitova-Cornell, Richard A. Moffitt, Yin Fei Tan, Igor Astsaturov, Ralph Francescone, Erica A. Golemis, Ido Sloma, Tiffiney R. Hartman
Publikováno v:
Cancer Cell. 38:567-583.e11
Oncogenic transformation alters lipid metabolism to sustain tumor growth. We define a mechanism by which cholesterol metabolism controls the development and differentiation of pancreatic ductal adenocarcinoma (PDAC). Disruption of distal cholesterol