Zobrazeno 1 - 10
of 186
pro vyhledávání: '"Aiyuan, Wang"'
Autor:
Haoye Meng, Xuejian Liu, Ronghui Liu, Yudong Zheng, Angyang Hou, Shuyun Liu, Wei He, Yu Wang, Aiyuan Wang, Quanyi Guo, Jiang Peng
Publikováno v:
Journal of Orthopaedic Translation, Vol 46, Iss , Pp 18-32 (2024)
Background: Osteochondral regeneration has long been recognized as a complex and challenging project in the field of tissue engineering. In particular, reconstructing the osteochondral interface is crucial for determining the effectiveness of the rep
Externí odkaz:
https://doaj.org/article/ae9b1336ae3241528a4a906f150d0425
Autor:
Ziping Niu, Chen Chen, Siyu Wang, Congcong Lu, Zhiyue Wu, Aiyuan Wang, Jing Mo, Jianji Zhang, Yanpu Han, Ye Yuan, Yingao Zhang, Yong Zang, Chaoran He, Xue Bai, Shanshan Tian, Guijin Zhai, Xudong Wu, Kai Zhang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Lysine lactylation (Kla) links metabolism and gene regulation and plays a key role in multiple biological processes. However, the regulatory mechanism and functional consequence of Kla remain to be explored. Here, we report that HBO1 functio
Externí odkaz:
https://doaj.org/article/d7a24dd19c6f46a4b218889f3153a2f2
Autor:
Yong Zang, Aiyuan Wang, Jianji Zhang, Mingxin Xia, Zixin Jiang, Bona Jia, Congcong Lu, Chen Chen, Siyu Wang, Yingao Zhang, Chen Wang, Xinyi Cao, Ziping Niu, Chaoran He, Xue Bai, Shanshan Tian, Guijin Zhai, Hailong Cao, Yupeng Chen, Kai Zhang
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110188- (2024)
Summary: Hypoxia promotes tumorigenesis and lactate accumulation in esophageal squamous cell carcinoma (ESCC). Lactate can induce histone lysine lactylation (Kla, a recently identified histone marks) to regulate transcription. However, the functional
Externí odkaz:
https://doaj.org/article/3b2073a3417144adabe213716af3dd57
Autor:
Jie Shang, Siyu Wang, Aiyuan Wang, Fang Li, Jing Zhang, Jin Wang, Rui Lv, Haixia Chen, Xiaohuan Mu, Kai Zhang, Xiaohong Bai, Ye Tian
Publikováno v:
Reproductive Biology and Endocrinology, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background Polycystic ovary syndrome (PCOS) is the main cause of anovulatory infertility in women of reproductive age, and low-grade chronic inflammation plays a key role in the occurrence and development of PCOS. However, obesity, as a like
Externí odkaz:
https://doaj.org/article/b27b3554fb164e978c7a88cd67e57fdb
Autor:
Weijia Sun, Yuheng Li, Jianwei Li, Yingjun Tan, Xinxin Yuan, Haoye Meng, Jianting Ye, Guohui Zhong, XiaoYan Jin, Zizhong Liu, Ruikai Du, Wenjuan Xing, Dingsheng Zhao, Jinping Song, Youyou Li, Junjie Pan, Yunzhang Zhao, Qi Li, Aiyuan Wang, Shukuan Ling, Rongji Dai, Yingxian Li
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
Abstract Mechanical force loading is essential for maintaining bone homeostasis, and unloading exposure can lead to bone loss. Osteoclasts are the only bone resorbing cells and play a crucial role in bone remodeling. The molecular mechanisms underlyi
Externí odkaz:
https://doaj.org/article/b3b4a4799a66481cb95d9ea2f7d7a2a2
Autor:
Jun Zhao, Haoye Meng, Sida Liao, Yaoyu Su, Li Guo, Aiyuan Wang, Wenjing Xu, Hao Zhou, Jiang Peng
Publikováno v:
Journal of Orthopaedic Translation, Vol 37, Iss , Pp 126-142 (2022)
Background: Osteonecrosis of the femoral head (ONFH) is a refractory disease due to its unclear pathomechanism. Therapies during the early stage of ONFH have not achieved satisfactory results. Therefore, this study aims to explore the available evide
Externí odkaz:
https://doaj.org/article/3a154753e35d46ecb47ffd33d199274f
Autor:
Guijin Zhai, Ziping Niu, Zixin Jiang, Fei Zhao, Siyu Wang, Chen Chen, Wei Zheng, Aiyuan Wang, Yong Zang, Yanpu Han, Kai Zhang
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 12/10/2024, Vol. 121 Issue 50, p1-9, 27p
Autor:
Yuxuan Zhang, Tao Lin, Haoye Meng, Xueting Wang, Hong Peng, Guangbo Liu, Shuai Wei, Qiang Lu, Yu Wang, Aiyuan Wang, Wenjing Xu, Huiping Shao, Jiang Peng
Publikováno v:
Journal of Orthopaedic Translation, Vol 33, Iss , Pp 13-23 (2022)
Background: /Objective: The treatment of bone defect has always been a difficult problem in orthopedic clinic. The search for alternative biodegradable implants is a hot topic. The development of biodegradable magnesium scaffolds for the treatment of
Externí odkaz:
https://doaj.org/article/a429b07ef2a4410b918ced08aa65fe66
Autor:
Weimin Guo, Mingxue Chen, Zhenyong Wang, Yue Tian, Jinxuan Zheng, Shuang Gao, Yangyang Li, Yufeng Zheng, Xu Li, Jingxiang Huang, Wei Niu, Shuangpeng Jiang, Chunxiang Hao, Zhiguo Yuan, Yu Zhang, Mingjie Wang, Zehao Wang, Jiang Peng, Aiyuan Wang, Yu Wang, Xiang Sui, Wenjing Xu, Libo Hao, Xifu Zheng, Shuyun Liu, Quanyi Guo
Publikováno v:
Bioactive Materials, Vol 6, Iss 10, Pp 3620-3633 (2021)
Despite intensive effort was made to regenerate injured meniscus by cell-free strategies through recruiting endogenous stem/progenitor cells, meniscus regeneration remains a great challenge in clinic. In this study, we found decellularized meniscal e
Externí odkaz:
https://doaj.org/article/5138d62ff6f8423c8f9c74eaf2dd60aa
Autor:
Tao Yang, Maryam Tamaddon, Le Jiang, Jing Wang, Ziyu Liu, Zhongqun Liu, Haoye Meng, Yongqiang Hu, Jianming Gao, Xuan Yang, Yanxu Zhao, Yanling Wang, Aiyuan Wang, Qiong Wu, Chaozong Liu, Jiang Peng, Xiaodan Sun, Qingyun Xue
Publikováno v:
Journal of Orthopaedic Translation, Vol 30, Iss , Pp 112-121 (2021)
Background/Objective: We seek to figure out the effect of stable and powerful mechanical microenvironment provided by Ti alloy as a part of subchondral bone scaffold on long-term cartilage regeneration.Methods: we developed a bilayered osteochondral
Externí odkaz:
https://doaj.org/article/fb9d1df392e84fbb8929ac878fa9ec35