Exploring computational approaches to design mRNA Vaccine against vaccinia and Mpox viruses.

Autor: Oladipo EK; Division of Vaccine Design and Development, Helix Biogen Institute, Ogbomoso, Oyo State, Nigeria.; Laboratory of Molecular Biology, Immunology and Bioinformatics, Department of Microbiology, Adeleke University, Ede, Osun State, Nigeria., Oyelakin OD; Division of Vaccine Design and Development, Helix Biogen Institute, Ogbomoso, Oyo State, Nigeria., Aiyelabegan AO; Division of Vaccine Design and Development, Helix Biogen Institute, Ogbomoso, Oyo State, Nigeria., Olajide EO; Division of Vaccine Design and Development, Helix Biogen Institute, Ogbomoso, Oyo State, Nigeria.; Molecular Biology and Biotechnology Department, Nigeria Institute of Medical Research, Lagos, Nigeria., Olatayo VO; Division of Vaccine Design and Development, Helix Biogen Institute, Ogbomoso, Oyo State, Nigeria., Owolabi KP; Division of Vaccine Design and Development, Helix Biogen Institute, Ogbomoso, Oyo State, Nigeria., Shittu YB; Division of Vaccine Design and Development, Helix Biogen Institute, Ogbomoso, Oyo State, Nigeria., Olugbodi RO; Division of Vaccine Design and Development, Helix Biogen Institute, Ogbomoso, Oyo State, Nigeria., Ajala HA; Division of Vaccine Design and Development, Helix Biogen Institute, Ogbomoso, Oyo State, Nigeria., Rukayat RA; Division of Vaccine Design and Development, Helix Biogen Institute, Ogbomoso, Oyo State, Nigeria., Olayiwola DO; Division of Vaccine Design and Development, Helix Biogen Institute, Ogbomoso, Oyo State, Nigeria., Irewolede BA; Division of Vaccine Design and Development, Helix Biogen Institute, Ogbomoso, Oyo State, Nigeria., Jimah EM; Division of Vaccine Design and Development, Helix Biogen Institute, Ogbomoso, Oyo State, Nigeria., Oloke JK; Department of Natural Sciences, Precious Cornerstone University, Ibadan, Oyo State, Nigeria., Ojo TO; Division of Vaccine Design and Development, Helix Biogen Institute, Ogbomoso, Oyo State, Nigeria., Ajani OF; African Centre for Disease Control HQ, Addis Ababa, Ethiopia., Iwalokun BA; Molecular Biology and Biotechnology Department, Nigeria Institute of Medical Research, Lagos, Nigeria., Kolawole OM; Department of Microbiology, University of Ilorin, Ilorin, Kwara State, Nigeria., Ariyo OE; Department of Medicine, Infectious Disease and Tropical Medicine Unit, Federal Teaching Hospital, Ido Ekiti, Ekiti State, Nigeria., Adediran DA; Division of Vaccine Design and Development, Helix Biogen Institute, Ogbomoso, Oyo State, Nigeria.; Department of Biochemistry, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria., Olufemi SE; Division of Vaccine Design and Development, Helix Biogen Institute, Ogbomoso, Oyo State, Nigeria.; Department of Biochemistry, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria., Onyeaka H; School of Chemical Engineering, University of Birmingham, Birmingham, UK.

Publikováno v: Immunity, inflammation and disease [Immun Inflamm Dis] 2024 Aug; Vol. 12 (8), pp. e1360.

Quantum evaluation and therapeutic activity of (E)-N-(4-methoxyphenyl)-2-(4-(3-oxo-3-phenylprop-1-en-1-yl) phenoxy)acetamide and its modified derivatives against EGFR and VEGFR-2 in the treatment of triple-negative cancer via in silico approach.

Autor: Ipinloju N; Theoretical and Computational Chemistry Unit, Department of Chemical Sciences, Adekunle Ajasin University, Akungba Akoko, Ondo State, Nigeria. Nureniipinloju@gmail.com., Ibrahim A; Department of Biochemistry and Molecular Biology, Usmanu Danfodiyo University, Sokoto, Nigeria. Ibrahimabdulwasiu44@gmail.com., da Costa RA; Institute of Education, Science and Technology of Para (IFPA), Campus Abaetetuba, Abaetetuba, Para, Brazil., Adigun TB; GWATAVRI Research and Biotechnology Nigeria Limited, Lagos, Nigeria., Olubode SO; Department of Biochemistry, Adekunle Ajasin University, Akungba Akoko, Ondo State, Nigeria., Abayomi KJ; Faculty of Medical Laboratory Science, Usmanu DanFodiyo University, Sokoto, Nigeria., Aiyelabegan AO; Biology Unit, Department of Biological Sciences, Usmanu Danfodiyo University, Sokoto, Nigeria., Esan TO; Department of Chemical Sciences, Bamidele Olumilua University of Education Science and Technology, Ikere-Ekiti, Ekiti State, Nigeria., Muhammad SA; Department of Biochemistry and Molecular Biology, Usmanu Danfodiyo University, Sokoto, Nigeria., Oyeneyin OE; Theoretical and Computational Chemistry Unit, Department of Chemical Sciences, Adekunle Ajasin University, Akungba Akoko, Ondo State, Nigeria. oluwatoba.oyeneyin@aaua.edu.ng.

Publikováno v: Journal of molecular modeling [J Mol Model] 2023 Apr 26; Vol. 29 (5), pp. 159. Date of Electronic Publication: 2023 Apr 26.