Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Aixin Yan"'
Autor:
Huimin He, Xi Wei, Bin Yang, Hongzhen Liu, Mingze Sun, Yanran Li, Aixin Yan, Chuyang Y. Tang, Yuan Lin, Lizhi Xu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-8 (2022)
Three-dimensional (3D) microfibrillar network represents an important structural design for various natural tissues and synthetic aerogels but achieving high mechanical properties for synthetic 3D microfibrillar networks remains challenging. Here, th
Externí odkaz:
https://doaj.org/article/9a8057c89e6e4299a475602bcc29235f
Autor:
Shugang Qin, Yongan Liu, Yuting Chen, Jinrong Hu, Wen Xiao, Xiaoshan Tang, Guohong Li, Ping Lin, Qinqin Pu, Qun Wu, Chuanmin Zhou, Biao Wang, Pan Gao, Zhihan Wang, Aixin Yan, Khan Nadeem, Zhenwei Xia, Min Wu
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 5 (2022)
ABSTRACT The therapeutic use of bacteriophages (phages) provides great promise for treating multidrug-resistant (MDR) bacterial infections. However, an incomplete understanding of the interactions between phages and bacteria has negatively impacted t
Externí odkaz:
https://doaj.org/article/9e44cc67cd874c6f9960b32c3bf27100
Autor:
Haibo Wang, Minji Wang, Xiaohan Xu, Peng Gao, Zeling Xu, Qi Zhang, Hongyan Li, Aixin Yan, Richard Yi-Tsun Kao, Hongzhe Sun
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Silver (Ag) has been used as an antimicrobial agent since a long time, but its molecular mechanism of action was not elucidated due to technical challenges. Here, the authors develop a mass spectrometric approach to identify the Ag-proteome in Staphy
Externí odkaz:
https://doaj.org/article/793574555794407d804bad3dd59bbdde
Autor:
Yu Li, Zeling Xu, Wenkai Han, Huiluo Cao, Ramzan Umarov, Aixin Yan, Ming Fan, Huan Chen, Carlos M. Duarte, Lihua Li, Pak-Leung Ho, Xin Gao
Publikováno v:
Microbiome, Vol 9, Iss 1, Pp 1-12 (2021)
Abstract Background The spread of antibiotic resistance has become one of the most urgent threats to global health, which is estimated to cause 700,000 deaths each year globally. Its surrogates, antibiotic resistance genes (ARGs), are highly transmit
Externí odkaz:
https://doaj.org/article/6a62358d67c749c99382697d2a9a8015
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/10e07cf0e2244eec96740d2e17940dd6
Autor:
Hongzhe Sun, Qi Zhang, Runming Wang, Haibo Wang, Yuen-Ting Wong, Minji Wang, Quan Hao, Aixin Yan, Richard Yi-Tsun Kao, Pak-Leung Ho, Hongyan Li
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Multi-drug resistant pathogens remain a serious public health threat. Here, Sun and colleagues identify a role for auranofin, which is normally used as a drug for rheumatoid arthritis, for reversing antibiotic resistance to carbapenem and colistin.
Externí odkaz:
https://doaj.org/article/f7e57cb418f248e6bdad5f3c045c4159
Publikováno v:
STAR Protocols, Vol 1, Iss 1, Pp 100039- (2020)
SUMMARY: Repurposing the broadly distributed native CRISPR-Cas systems in prokaryotes for genome editing is emerging as a new strategy for genetic manipulations. We recently reported the establishment of a single plasmid-mediated, one-step genome-edi
Externí odkaz:
https://doaj.org/article/7d0ff84fb0224e5b97bac3e42053a219
Autor:
Haibo Wang, Minji Wang, Xiaohan Xu, Peng Gao, Zeling Xu, Qi Zhang, Hongyan Li, Aixin Yan, Richard Yi-Tsun Kao, Hongzhe Sun
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/e5a0e9f0a0fa4a359a7565148792ad96
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-17 (2017)
Abstract Background Pseudomonas aeruginosa ATCC 27853 was isolated from a hospital blood specimen in 1971 and has been widely used as a model strain to survey antibiotics susceptibilities, biofilm development, and metabolic activities of Pseudomonas
Externí odkaz:
https://doaj.org/article/56ccc5c55f15449c87f6356f0a4d7c29
Autor:
Zeling Xu, Ming Li, Yanran Li, Huiluo Cao, Lu Miao, Zhaochao Xu, Yusuke Higuchi, Seiji Yamasaki, Kunihiko Nishino, Patrick C.Y. Woo, Hua Xiang, Aixin Yan
Publikováno v:
Cell Reports, Vol 29, Iss 6, Pp 1707-1717.e3 (2019)
Summary: Despite being fundamentally important and having direct therapeutic implications, the functional genomics of the clinical isolates of multidrug-resistant (MDR) pathogens is often impeded by the lack of genome-editing tools. Here, we report t
Externí odkaz:
https://doaj.org/article/4fbc24c8ae9a4183affd002c99d411b5