Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Aiwu Ke"'
Autor:
Yilan Huang, Siwei Wang, Xiaojun Zhang, Chen Yang, Sikai Wang, Hongxia Cheng, Aiwu Ke, Chao Gao, Kun Guo
Publikováno v:
Pharmacological Research, Vol 200, Iss , Pp 107082- (2024)
Lenvatinib is a frontline tyrosine kinase inhibitor for patients with advanced hepatocellular carcinoma (HCC). However, just 25% of patients benefit from the treatment, and acquired resistance always develops. To date, there are neither effective med
Externí odkaz:
https://doaj.org/article/78a80cba6d904197997d6bee59908af5
Autor:
Xiaoqiang Chai, Jie Wang, Huanping Li, Chao Gao, Shuangqi Li, Chuanyuan Wei, Jianhang Huang, Yingming Tian, Jian Yuan, Jiacheng Lu, Dongmei Gao, Yimin Zheng, Cheng Huang, Jian Zhou, Guoming Shi, Aiwu Ke, Feng Liu, Jia Fan, Jiabin Cai
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTIntrahepatic cholangiocarcinoma (ICC) is a rare malignancy with a high prevalence in China. This study aimed to characterize the ICC tissues’ bacterial metagenomics signature and explore its antitumor potential for cancer. In this study, 16
Externí odkaz:
https://doaj.org/article/41c480b6c6ab4540a66b7e8eb9a9f33d
Autor:
Yimin Zheng, Yining Wang, Zhou Lu, Jinkai Wan, Lulu Jiang, Danjun Song, Chuanyuan Wei, Chao Gao, Guoming Shi, Jian Zhou, Jia Fan, Aiwu Ke, Lu Zhou, Jiabin Cai
Publikováno v:
Advanced Science, Vol 10, Iss 29, Pp n/a-n/a (2023)
Abstract The combination of immunotherapy and molecular targeted therapy exhibits promising therapeutic efficacy in hepatocellular carcinoma (HCC), but the underlying mechanism is still unclear. Here, phosphoglycerate mutase 1 (PGAM1) is identified a
Externí odkaz:
https://doaj.org/article/15126f03d9824effbdca99cc5e848d12
Autor:
Xiaogang Li, Zheng Gao, Jiafeng Chen, Shanru Feng, Xuanming Luo, Yinghong Shi, Zheng Tang, Weiren Liu, Xin Zhang, Ao Huang, Qiang Gao, Aiwu Ke, Jian Zhou, Jia Fan, Xiutao Fu, Zhenbin Ding
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundVarious immune cell types in the tumor microenvironment (TME) of hepatocellular carcinoma (HCC) have been identified as important parameters associated with prognosis and responsiveness to immunotherapy. However, how various factors influen
Externí odkaz:
https://doaj.org/article/54ec176c846243e686ca13adc013ca8a
Publikováno v:
Genes and Diseases, Vol 10, Iss 2, Pp 370-372 (2023)
Externí odkaz:
https://doaj.org/article/b2ba9518343647e58f61dac20d607183
Autor:
Minghao Xu, Chenhao Zhou, Jialei Weng, Zhaoshuo Chen, Qiang Zhou, Jian Gao, Guoming Shi, Aiwu Ke, Ning Ren, Huichuan Sun, Yinghao Shen
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-17 (2022)
Abstract Background Tumor-associated macrophages (TAMs), which form a large part of the tumor microenvironment, are normally regulated by metabolic reprogramming. However, the potential mechanisms of the immune-metabolism interaction between hepatoce
Externí odkaz:
https://doaj.org/article/60783d96a3214def8698d756601f1a72
Autor:
Guohe Song, Yang Shi, Lu Meng, Jiaqiang Ma, Siyuan Huang, Juan Zhang, Yingcheng Wu, Jiaxin Li, Youpei Lin, Shuaixi Yang, Dongning Rao, Yifei Cheng, Jian Lin, Shuyi Ji, Yuming Liu, Shan Jiang, Xiaoliang Wang, Shu Zhang, Aiwu Ke, Xiaoying Wang, Ya Cao, Yuan Ji, Jian Zhou, Jia Fan, Xiaoming Zhang, Ruibin Xi, Qiang Gao
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
The molecular classification and tumour microenvironment in intrahepatic cholangiocarcinoma (iCCA) need further characterisation. Here, the authors perform single cell RNA-sequencing from 14 pairs of iCCA tumours and non-tumour liver tissues and prop
Externí odkaz:
https://doaj.org/article/d1872e649e1344dba5a7cc26ee3c1275
Autor:
Guohe Song, Yang Shi, Meiying Zhang, Shyamal Goswami, Saifullah Afridi, Lu Meng, Jiaqiang Ma, Yi Chen, Youpei Lin, Juan Zhang, Yuming Liu, Zijie Jin, Shuaixi Yang, Dongning Rao, Shu Zhang, Aiwu Ke, Xiaoying Wang, Ya Cao, Jian Zhou, Jia Fan, Xiaoming Zhang, Ruibin Xi, Qiang Gao
Publikováno v:
Cell Discovery, Vol 6, Iss 1, Pp 1-15 (2020)
Abstract Diverse immune cells in the tumor microenvironment form a complex ecosystem, but our knowledge of their heterogeneity and dynamics within hepatocellular carcinoma (HCC) still remains limited. To assess the plasticity and phenotypes of immune
Externí odkaz:
https://doaj.org/article/c5a666494abc4fdc99a5041b4b14afe1
Autor:
Shilin Gao, Jiahao Jiang, Chun Jin, Jian Gao, Dian Xiong, Pengjie Yang, Shuzhong Cui, Wenhao Yang, Qibin Leng, Jihong Dong, Gang Chen, Junzhen Liu, Li Wang, Aiwu Ke, Haikun Wang, Jianyong Ding
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Imaging methods, such as CT or MRI, cannot provide accurate diagnosis between malignant thymomas and other thymic abnormalities. Here the authors show that the levels of IL-8 in circulating naive T cells are elevated in patients with thymoma compared
Externí odkaz:
https://doaj.org/article/bd9d4a713ea54cb09adcde48f592857c
Autor:
Guohe Song, Yang Shi, Lu Meng, Jiaqiang Ma, Siyuan Huang, Juan Zhang, Yingcheng Wu, Jiaxin Li, Youpei Lin, Shuaixi Yang, Dongning Rao, Yifei Cheng, Jian Lin, Shuyi Ji, Yuming Liu, Shan Jiang, Xiaoliang Wang, Shu Zhang, Aiwu Ke, Xiaoying Wang, Ya Cao, Yuan Ji, Jian Zhou, Jia Fan, Xiaoming Zhang, Ruibin Xi, Qiang Gao
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/d0f908c656ea4fb5966c094e6f65bf0c