Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Aitor Urosa"'
Autor:
Aitor Urosa, Ignacio E Tobal, Ángela P de la Granja, M Carmen Capitán, R F Moro, Isidro S Marcos, Narciso M Garrido, Francisca Sanz, Emilio Calle, David Díez
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192113 (2018)
A novel approach to the production of chiral 1,3-cyclohexadienals has been developed. The organocatalysed asymmetric reaction of different β-disubstituted-α,β-unsaturated aldehydes with a chiral α,β-unsaturated aldehyde in the presence of a Jør
Externí odkaz:
https://doaj.org/article/74c0bd6235c94cbb88c132080f7fe834
Autor:
Aitor Urosa, Isidro S. Marcos, David Díez, Anna Lithgow, Gabriela B. Plata, José M. Padrón, Pilar Basabe
Publikováno v:
Marine Drugs, Vol 13, Iss 4, Pp 2407-2423 (2015)
The first synthesis of Luffarin I, sesterterpenolide isolated from sponge Luffariella geometrica, has been accomplished from commercially available sclareol. The key strategy involved in this synthesis is the diastereoselective reduction of an interm
Externí odkaz:
https://doaj.org/article/3cda19a8e89242b5af5add8d57c678f4
Autor:
Aitor Urosa Guarido
Publikováno v:
GREDOS. Repositorio Institucional de la Universidad de Salamanca
instname
instname
[ES]El ecosistema marino que ocupa más del 70% de la superficie terrestre, es una fuente muy rica en productos químicos con actividad biológica. Muchos organismos marinos son muy sensibles al ataque de depredadores y por tanto, han desarrollado me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::925e8535466339fa2efa2cd5dd1a01fb
https://doi.org/10.14201/gredos.128292
https://doi.org/10.14201/gredos.128292
Ring-closing metathesis as key step in the synthesis of Luffarin I, 16-epi-Luffarin I and Luffarin A
Publikováno v:
Molecular Diversity. 20:369-377
Natural sesterterpenolides, luffarin I and luffarin A, from Luffariella geometrica have been synthesized, and this is the first reported synthesis of luffarin A. The Yamaguchi esterification of the nor-diterpenic fragment, obtained from 2.8-15μM, wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a22f367db5e88ef484f33ef7ef667a07
https://doi.org/10.1007/s11030-015-9638-7
https://doi.org/10.1007/s11030-015-9638-7
Publikováno v:
The Journal of Organic Chemistry. 80:6447-6455
The first synthesis of luffarin L (1) and 16-epi-luffarin L (2) by a silicon-tethered ring closing metathesis as a key step has been achieved. The stereochemistry and absolute configuration of the natural sesterterpenolide luffarin L (1) and a new ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e1e4e2f8503d249d11a60253a1f4325
https://doi.org/10.1021/acs.joc.5b00876
https://doi.org/10.1021/acs.joc.5b00876
Publikováno v:
The Journal of Organic Chemistry. 80:4566-4572
Sesterterpenes with a salmahyrtisane skeleton have been synthesized for the first time. (-)-Sclareol has been selected as a precursor for the synthesis of two novel natural products: salmahyrtisol A (1) and hippospongide A (2). Our results represent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75ebe38a5f8cba874842787a53047d15
https://doi.org/10.1021/acs.joc.5b00420
https://doi.org/10.1021/acs.joc.5b00420
Autor:
Pilar Basabe, Anna M. Lithgow, David Díez, Aitor Urosa, José M. Padrón, Gabriela B. Plata, Isidro S. Marcos
Publikováno v:
Marine Drugs
Volume 13
Issue 4
Pages 2407-2423
Marine Drugs, Vol 13, Iss 4, Pp 2407-2423 (2015)
Volume 13
Issue 4
Pages 2407-2423
Marine Drugs, Vol 13, Iss 4, Pp 2407-2423 (2015)
The first synthesis of Luffarin I, sesterterpenolide isolated from sponge Luffariella geometrica, has been accomplished from commercially available sclareol. The key strategy involved in this synthesis is the diastereoselective reduction of an interm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d25cc053c7ddf3b7b0bda2ccfdadd37
http://europepmc.org/articles/PMC4413218
http://europepmc.org/articles/PMC4413218
Autor:
Francisca Sanz, David Díez, M. Carmen Capitán, Isidro S. Marcos, Aitor Urosa, Ignacio E. Tobal, Emilio Calle, Narciso M. Garrido, Ángela P. de la Granja, Rosalina F. Moro
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192113 (2018)
GREDOS. Repositorio Institucional de la Universidad de Salamanca
instname
PLoS ONE
GREDOS. Repositorio Institucional de la Universidad de Salamanca
instname
PLoS ONE
[EN] A novel approach to the production of chiral 1,3-cyclohexadienals has been developed. The organocatalysed asymmetric reaction of different β-disubstituted-α,β-unsaturated aldehydes with a chiral α,β-unsaturated aldehyde in the presence of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20f036a836985a3bffa36930bd246985
https://doi.org/10.1371/journal.pone.0192113
https://doi.org/10.1371/journal.pone.0192113
Publikováno v:
ChemInform. 46
Amongst some intermediates, salmahyrtisol A (I) has been tested on its antiproliferative activity against human tumor cell lines A549 (lung), HBL-100 (lung), HeLa (cervix), SW1573 (lung), T-47D (breast) and WiDr (colon).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e44c8cffd2b58ba72b7858bae8e37609
https://doi.org/10.1002/chin.201537215
https://doi.org/10.1002/chin.201537215