Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Aitor Maestro"'
Publikováno v:
Molbank, Vol 2022, Iss 3, p M1424 (2022)
Bisphosphonates are widely used in medicine and related areas, mainly for the treatment of bone diseases, such as osteoporosis. However, their synthesis is usually performed under harsh reaction conditions. In order to overcome this limitation, the p
Externí odkaz:
https://doaj.org/article/c832c68155c94c8e894303a220be1fce
Publikováno v:
Molecules, Vol 27, Iss 22, p 8024 (2022)
An efficient general method for the synthesis of a wide family of α-aminophosphonate analogs of aspartic acid bearing tetrasubstituted carbons is reported through an aza-Reformatsky reaction of α-iminophosphonates, generated from α-aminophosphonat
Externí odkaz:
https://doaj.org/article/72174b54dc9441038d63372416fada64
Autor:
Xabier del Corte, Adrián López-Francés, Aitor Maestro, Ilia Villate-Beitia, Myriam Sainz-Ramos, Edorta Martínez de Marigorta, José Luis Pedraz, Francisco Palacios, Javier Vicario
Publikováno v:
Pharmaceuticals, Vol 14, Iss 8, p 782 (2021)
An efficient synthetic methodology for the preparation of 3-amino 1,5-dihydro-2H-pyrrol-2-ones through a multicomponent reaction of amines, aldehydes, and pyruvate derivatives is reported. In addition, the densely substituted lactam substrates show i
Externí odkaz:
https://doaj.org/article/e375b54fa6eb47ecb582cc7e02854683
Autor:
Aitor Maestro, Xabier del Corte, Adrián López-Francés, Edorta Martínez de Marigorta, Francisco Palacios, Javier Vicario
Publikováno v:
Molecules, Vol 26, Iss 11, p 3202 (2021)
Due to their structural similarity with natural α-amino acids, α-aminophosphonic acid derivatives are known biologically active molecules. In view of the relevance of tetrasubstituted carbons in nature and medicine and the strong dependence of the
Externí odkaz:
https://doaj.org/article/8e64a6abbfbb4ff6afa51c93f1e8e9d5
Autor:
Mercedes Zurro, Aitor Maestro
Publikováno v:
ChemCatChem.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e9c8db2665b25018342c0b4c4a6c8d6
https://doi.org/10.1002/cctc.202300500
https://doi.org/10.1002/cctc.202300500
Publikováno v:
Organic letters, 24(5), 1228-1231. AMER CHEMICAL SOC INC
Herein we report the first alkynylation of quinolones with terminal alkynes under mild reaction conditions. The reaction is catalyzed by Cu(I) salts in the presence of a Lewis acid, which is essential for the reactivity of the system. The enantiosele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63b931e588606606291daa73a7e4c460
https://doi.org/10.1021/acs.orglett.2c00020
https://doi.org/10.1021/acs.orglett.2c00020
Autor:
F Palacios, Xabier Del Corte Solaguren-Beascoa, Javier Vicario, Aitor Maestro, Edorta Martinez de Marigorta
Publikováno v:
Organic Chemistry Frontiers. 9:6331-6399
Since 2004, chiral phosphoric acids (CPAs) have emerged as highyl efficient organocatalysts, providing excellent results in a wide reaction scope. In this review, the applications of CPA for enantioselective additions to CO and CN bonds are covered.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::475a3b2cbc30c37f5f9e5571347ab70b
https://doi.org/10.1039/d2qo01209j
https://doi.org/10.1039/d2qo01209j
Publikováno v:
Asian Journal of Organic Chemistry. 9:538-548
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc054d3466942712ea9e14bd216af592
https://doi.org/10.1002/ajoc.202000039
https://doi.org/10.1002/ajoc.202000039
Autor:
F Palacios, Xabier Del Corte Solaguren-Beascoa, Javier Vicario, Aitor Maestro, Adrián López-Francés
Publikováno v:
Molecules; Volume 27; Issue 22; Pages: 8024
An efficient general method for the synthesis of a wide family of α-aminophosphonate analogs of aspartic acid bearing tetrasubstituted carbons is reported through an aza-Reformatsky reaction of α-iminophosphonates, generated from α-aminophosphonat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2244f4c19f3aaa10ad48467d47d21e5
https://doi.org/10.3390/molecules27228024
https://doi.org/10.3390/molecules27228024
Publikováno v:
Organic Letters. 21:9473-9477
Here, an enantioselective aza-Reformatsky reaction using acyclic ketimine substrates is presented. Using α-phosphorated ketimines as electrophilic substrates and a simple BINOL-derived ligand, phosphorated analogues of aspartic acid holding chiral t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8c6c73cf81a9e1b298d53aae5d28c81
https://doi.org/10.1021/acs.orglett.9b03669
https://doi.org/10.1021/acs.orglett.9b03669