Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Aitor Delmiro"'
Autor:
Miguel Fernández de la Torre, Carmen Fiuza-Luces, Sara Laine-Menéndez, Aitor Delmiro, Joaquín Arenas, Miguel Ángel Martín, Alejandro Lucia, María Morán
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 10973 (2023)
By means of a proteomic approach, we assessed the pathways involved in cerebellar neurodegeneration in a mouse model (Harlequin, Hq) of mitochondrial disorder. A differential proteomic profile study (iTRAQ) was performed in cerebellum homogenates of
Externí odkaz:
https://doaj.org/article/8c3cc157302a40b78708952deb228cdc
Autor:
Pablo Serrano-Lorenzo, Olga N. Coya, Ana López-Jimenez, Alberto Blázquez, Aitor Delmiro, Alejandro Lucia, Joaquín Arenas, Miguel A. Martín, Alejandro Santos-Lozano, Cecilia Cueto-Felgueroso, Alba Fernández-del Pozo, Montserrat de Miguel-Reyes
Publikováno v:
Practical Laboratory Medicine, Vol 25, Iss , Pp e00226- (2021)
Objectives: We aimed to determine whether the plasma profile of lactate dehydrogenase (LDH) isoenzymes is altered in patients with COVID-19, and whether this is attributable to a specific release of LDH-3, the main LDH isoenzyme expressed in lungs. D
Externí odkaz:
https://doaj.org/article/12f57ff30b3942ab8e8d433597710090
Autor:
Nuria Bujan, Constanza Morén, Francesc J. García-García, Alberto Blázquez, Clara Carnicer, Ana Belén Cortés, Cristina González, Ester López-Gallardo, Ester Lozano, Sonia Moliner, Laura Gort, Ester Tobías, Aitor Delmiro, Miguel Ángel Martin, Miguel Ángel Fernández-Moreno, Eduardo Ruiz-Pesini, Elena Garcia-Arumí, Juan Carlos Rodríguez-Aguilera, Glòria Garrabou
Publikováno v:
Antioxidants, Vol 11, Iss 4, p 741 (2022)
The quantification of mitochondrial respiratory chain (MRC) enzymatic activities is essential for diagnosis of a wide range of mitochondrial diseases, ranging from inherited defects to secondary dysfunctions. MRC lesion is frequently linked to extend
Externí odkaz:
https://doaj.org/article/d0611c0ec08947eb8c86d361cf171d51
Autor:
Sara Laine-Menéndez, Miguel Fernández-de la Torre, Carmen Fiuza-Luces, Aitor Delmiro, Joaquín Arenas, Miguel Ángel Martín, Patricia Boya, Alejandro Lucia, María Morán
Publikováno v:
Antioxidants, Vol 11, Iss 3, p 510 (2022)
We analyzed the effects of apoptosis-inducing factor (AIF) deficiency, as well as those of an exercise training intervention on autophagy across tissues (heart, skeletal muscle, cerebellum and brain), that are primarily affected by mitochondrial dise
Externí odkaz:
https://doaj.org/article/89b90c5d5e664138946534ba35dda509
Autor:
Sara Laine-Menéndez, Cristina Domínguez-González, Alberto Blázquez, Aitor Delmiro, Inés García-Consuegra, Miguel Fernández-de la Torre, Aurelio Hernández-Laín, Javier Sayas, Miguel Ángel Martín, María Morán
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 5598 (2021)
Our goal was to analyze postmortem tissues of an adult patient with late-onset thymidine kinase 2 (TK2) deficiency who died of respiratory failure. Compared with control tissues, we found a low mtDNA content in the patient’s skeletal muscle, liver,
Externí odkaz:
https://doaj.org/article/acffa3f428ed4d09b1c0b948adb982b9
Autor:
Rafael Pérez-Pérez, Teresa Lobo-Jarne, Dusanka Milenkovic, Arnaud Mourier, Ana Bratic, Alberto García-Bartolomé, Erika Fernández-Vizarra, Susana Cadenas, Aitor Delmiro, Inés García-Consuegra, Joaquín Arenas, Miguel A. Martín, Nils-Göran Larsson, Cristina Ugalde
Publikováno v:
Cell Reports, Vol 16, Iss 9, Pp 2387-2398 (2016)
Mitochondrial respiratory chain (MRC) complexes I, III, and IV associate into a variety of supramolecular structures known as supercomplexes and respirasomes. While COX7A2L was originally described as a supercomplex-specific factor responsible for th
Externí odkaz:
https://doaj.org/article/57f6b2a6d31a4e268acc95b07dda5358
Autor:
FERNANDO GALLEGO-BUSTOS, VALER GOTEA, JOSE T RAMOS-AMADOR, REBECA RODRIGUEZ-PENA, JUANA GIL, ANA SASTRE, AITOR DELMIRO, GHADI RAI, LAURA ELNITSKI, LUIS I GONZÁLEZ-GRANADO, LUIS M ALLENDE
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
Reported synonymous substitutions are generally non-pathogenic and rare pathogenic synonymous variants may be disregarded unless there is a high index of suspicion. In a case of IL7 receptor deficiency SCID, the relevance of a non-reported synonymous
Externí odkaz:
https://doaj.org/article/23892115752e413987fa236584304422
Autor:
María Paz Guerrero‐Molina, Montserrat Morales‐Conejo, Aitor Delmiro, María Morán, Cristina Domínguez‐González, Elena Arranz‐Canales, Ana Ramos‐González, Joaquín Arenas, Miguel A. Martín, Jesús González de la Aleja
Publikováno v:
European Journal of Neurology. 30:538-547
Mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes (MELAS) syndrome is a genetically heterogeneous disorder caused by mitochondrial DNA mutations. There are no disease-modifying therapies, and treatment remains mainly supportiv
Autor:
Morán, Miguel Fernández de la Torre, Carmen Fiuza-Luces, Sara Laine-Menéndez, Aitor Delmiro, Joaquín Arenas, Miguel Ángel Martín, Alejandro Lucia, María
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 13; Pages: 10973
By means of a proteomic approach, we assessed the pathways involved in cerebellar neurodegeneration in a mouse model (Harlequin, Hq) of mitochondrial disorder. A differential proteomic profile study (iTRAQ) was performed in cerebellum homogenates of
Autor:
Aitor Delmiro, Pedro L. Valenzuela, Carlos Lumbreras, Elena A. López-Jiménez, Miguel Martín, José L. Eguiburu-Jaime, Alejandro Lucia, Jose M. Aguado, Antonio Lalueza, Joaquín Arenas
Publikováno v:
ABACUS. Repositorio de Producción Científica
Universidad Europea (UEM)
Universidad Europea (UEM)
Ministerio de Ciencia e Innovación de España, Instituto de Salud Carlos III (convocatoria de investigación COVID-19 COV20 / 00181) cofinanciado por el Fondo Regional Europeo de Desarrollo “Una forma de lograr Europa”. Ministerio de Asuntos Eco