Selective quantitative N-functionalization of unprotected α-amino acids using NHC-Ir(III) catalyst

Autor: Beatriz Saavedra, Aitor Bermejo-López, Majken Raeder, Belén Martín-Matute

Publikováno v: STAR Protocols, Vol 4, Iss 2, Pp 102147- (2023)

Summary: Unnatural amino acids are valuable building blocks with numerous applications. Here, we present a quantitative technique for accessing mono-N-functionalized amino acids directly from unprotected substrates using alcohols as alkylating agents

Externí odkaz: https://doaj.org/article/273baffe1857498d82d458d03a1939c0

Iron‐Catalyzed Borylation of Propargylic Acetates for the Synthesis of Multisubstituted Allenylboronates

Autor: Aitor Bermejo‐López, Wei‐Jun Kong, Pedro J. Tortajada, Daniels Posevins, Belén Martín‐Matute, Jan‐E. Bäckvall

Publikováno v: Chemistry – A European Journal. 29

A novel iron-catalyzed borylation of propargylic acetates leading to allenylboronates has been developed. The method allows the preparation of a variety of di-, tri- and tetrasubstituted allenylboronates at room temperature with good functional group

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5db4d19e0a09c615b32f90a5891bae37
https://doi.org/10.1002/chem.202203130

Corrigendum: Iron‐Catalyzed Cross‐Coupling of Propargyl Ethers with Grignard Reagents for the Synthesis of Functionalized Allenes and Allenols

Autor: Daniels Posevins, Aitor Bermejo‐López, Jan‐E. Bäckvall

Publikováno v: Angewandte Chemie International Edition. 61

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e6e7e6370641abd4ee6ad676b4a1f09d
https://doi.org/10.1002/anie.202212750

Selective Synthesis of Imines by Photo-Oxidative Amine Cross-Condensation Catalyzed by PCN-222(Pd)

Autor: Mathias S. Hvid, Nina Lock, Amparo Sanz-Marco, Kenji P. M. Kopf, Sergio Carrasco, Belén Martín-Matute, Pedro J. Tortajada, Aitor Bermejo-López

Publikováno v: Bermejo-López, A, Carrasco, S, Tortajada, P J, Kopf, K P M, Sanz-Marco, A, Hvid, M S, Lock, N & Martín-Matute, B 2021, ' Selective Synthesis of Imines by Photo-Oxidative Amine Cross-Condensation Catalyzed by PCN-222(Pd) ', ACS Sustainable Chemistry and Engineering, vol. 9, no. 43, pp. 14405-14415 . https://doi.org/10.1021/acssuschemeng.1c04389

Palladium-metalated PCN-222 enables the aerobic photo-oxidative cross-condensation of anilines with benzylic amines yielding a series of linear and cyclic imines. The reaction is very efficient under mild conditions, which allows the isolation of sim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0a77bd34f6d69527151c683cf53fc19
https://pure.au.dk/portal/da/publications/selective-synthesis-of-imines-by-photooxidative-amine-crosscondensation-catalyzed-by-pcn222pd(614836e0-c0e2-4f9f-a03c-5a86a3c0f7c6).html

Nonclassical Mechanism in the Cyclodehydration of Diols Catalyzed by a Bifunctional Iridium Complex

Autor: Greco, González Miera, Aitor, Bermejo López, Elisa, Martínez-Castro, Per-Ola, Norrby, Belén, Martín-Matute

Publikováno v: Chemistry (Weinheim an Der Bergstrasse, Germany)

1,4‐ and 1,5‐diols undergo cyclodehydration upon treatment with cationic N‐heterocyclic carbene (NHC)–IrIII complexes to give tetrahydrofurans and tetrahydropyrans, respectively. The mechanism was investigated, and a metal‐hydride‐driven

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c1aa7d04d3f8a7c27fb4c944ab436223
https://pubmed.ncbi.nlm.nih.gov/30475410