Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Aito Isoguchi"'
Autor:
Hiroaki Matsushita, Aito Isoguchi, Masamitsu Okada, Teruaki Masuda, Yohei Misumi, Chiharu Tsutsui, Narumi Yamaguchi, Yuko Ichiki, Jinko Sawashita, Mitsuharu Ueda, Mineyuki Mizuguchi, Yukio Ando
Publikováno v:
Heliyon, Vol 7, Iss 10, Pp e08101- (2021)
Transthyretin (TTR) is an amyloidogenic protein associated with hereditary and nonhereditary transthyretin amyloidoses (ATTR). Dissociation of the tetramer of TTR to the monomer induces TTR misfolding, which leads to amyloid fibril formation and trig
Externí odkaz:
https://doaj.org/article/03a2f18072db4675abecb2475a846c1f
Autor:
Toshiya Nomura, Mitsuharu Ueda, Masayoshi Tasaki, Yohei Misumi, Teruaki Masuda, Yasuteru Inoue, Yukimoto Tsuda, Masamitsu Okada, Takahiro Okazaki, Kyosuke Kanenawa, Aito Isoguchi, Makoto Nakamura, Konen Obayashi, Satoru Shinriki, Hirotaka Matsui, Taro Yamashita, Yukio Ando
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 14, Iss 1, Pp 1-6 (2019)
Abstract Background Hereditary transthyretin amyloidosis (ATTRv amyloidosis) is caused by a variant transthyretin (TTR), which is a serum protein secreted by the liver. Mass spectrometry (MS) is a useful tool that can detect variant TTRs in serum sam
Externí odkaz:
https://doaj.org/article/6c28f8900d21485d9f672cf6f921e96c
Autor:
Hiroaki Matsushita, Aito Isoguchi, Masamitsu Okada, Teruaki Masuda, Yohei Misumi, Yuko Ichiki, Mitsuharu Ueda, Yukio Ando
Publikováno v:
Biochemistry and Biophysics Reports, Vol 25, Iss , Pp 100875- (2021)
In the future, humans may live in space because of global pollution and weather fluctuations. In microgravity, convection does not occur, which may change the amyloidogenicity of proteins. However, the effect of gravity on amyloid fibril formation is
Externí odkaz:
https://doaj.org/article/76dde6db96604259bf1397e9446b0c36
Autor:
Yuko Ichiki, Teruaki Masuda, Yohei Misumi, Hiroaki Matsushita, Yukio Ando, Aito Isoguchi, Mitsuharu Ueda, Masamitsu Okada
Publikováno v:
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports, Vol 25, Iss, Pp 100875-(2021)
Biochemistry and Biophysics Reports, Vol 25, Iss, Pp 100875-(2021)
In the future, humans may live in space because of global pollution and weather fluctuations. In microgravity, convection does not occur, which may change the amyloidogenicity of proteins. However, the effect of gravity on amyloid fibril formation is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3833ea73c1aa209a1bd71126473f01b6
https://pubmed.ncbi.nlm.nih.gov/33364446
https://pubmed.ncbi.nlm.nih.gov/33364446
Autor:
Mayumi Mizukami, Akihiko Ueda, Taro Yamashita, Teruaki Masuda, Toshiya Nomura, Yasuteru Inoue, Hirotaka Matsui, Masamitsu Okada, Kyosuke Kanenawa, Yoshinobu Hoshii, Aito Isoguchi, Tessei Torikai, Masayoshi Tasaki, Yohei Misumi, Sayaka Matsumoto, Mitsuharu Ueda, Yukimoto Tsuda, Makoto Nakamura, Yukio Ando, Konen Obayashi
Publikováno v:
The Journal of Pathology. 247:444-455
Most intractable tissue-degenerative disorders share a common pathogenic condition, so-called proteinopathy. Amyloid-related disorders are the most common proteinopathies and are characterized by amyloid fibril deposits in the brain or other organs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc4cb8945286f349d349cc5c3139ab7a
https://doi.org/10.1002/path.5203
https://doi.org/10.1002/path.5203
Autor:
Yuko Ichiki, Yohei Misumi, Masamitsu Okada, Mineyuki Mizuguchi, Aito Isoguchi, Chiharu Tsutsui, Teruaki Masuda, Mitsuharu Ueda, Hiroaki Matsushita, Narumi Yamaguchi, Yukio Ando, Jinko Sawashita
Publikováno v:
Heliyon, Vol 7, Iss 10, Pp e08101-(2021)
Heliyon
Heliyon
Transthyretin (TTR) is an amyloidogenic protein associated with hereditary and nonhereditary transthyretin amyloidoses (ATTR). Dissociation of the tetramer of TTR to the monomer induces TTR misfolding, which leads to amyloid fibril formation and trig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cce4b5ddf0f7a6dff32e08f685455509
https://doi.org/10.1016/j.heliyon.2021.e08101
https://doi.org/10.1016/j.heliyon.2021.e08101
Autor:
Kyosuke, Kanenawa, Mitsuharu, Ueda, Aito, Isoguchi, Toshiya, Nomura, Yukimoto, Tsuda, Teruaki, Masuda, Yohei, Misumi, Taro, Yamashita, Yukio, Ando
Publikováno v:
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis. 26(sup1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2c8f07350618223808d6f4a64b30b76b
https://pubmed.ncbi.nlm.nih.gov/31343347
https://pubmed.ncbi.nlm.nih.gov/31343347
Autor:
Barbara Kluve-Beckerman, Mineyuki Mizuguchi, Masayoshi Tasaki, Akinori Kanai, Toshiya Nomura, Kyosuke Kanenawa, Satoru Shinriki, Mitsuharu Ueda, Ryoko Sasaki, Yukio Ando, Hirofumi Kai, Teruaki Masuda, Tsuyoshi Shuto, Hirotaka Matsui, Masamitsu Okada, Yohei Misumi, Merrill D. Benson, Akihiko Ueda, Aito Isoguchi, Taro Yamashita, Yasuteru Inoue
Publikováno v:
J Biol Chem
Transthyretin (TTR) is a major amyloidogenic protein associated with hereditary (ATTRm) and nonhereditary (ATTRwt) intractable systemic transthyretin amyloidosis. The pathological mechanisms of ATTR-associated amyloid fibril formation are incompletel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e48c31017e98e6e58277dbb722f7f07
https://europepmc.org/articles/PMC6643022/
https://europepmc.org/articles/PMC6643022/
Autor:
Mitsuharu Ueda, Hirotaka Matsui, Teruaki Masuda, Takahiro Okazaki, Yohei Misumi, Yukimoto Tsuda, Toshiya Nomura, Aito Isoguchi, Yukio Ando, Kyosuke Kanenawa, Makoto Nakamura, Konen Obayashi, Masayoshi Tasaki, Masamitsu Okada, Taro Yamashita, Yasuteru Inoue, Satoru Shinriki
Publikováno v:
Orphanet Journal of Rare Diseases
Orphanet Journal of Rare Diseases, Vol 14, Iss 1, Pp 1-6 (2019)
Orphanet Journal of Rare Diseases, Vol 14, Iss 1, Pp 1-6 (2019)
Background Hereditary transthyretin amyloidosis (ATTRv amyloidosis) is caused by a variant transthyretin (TTR), which is a serum protein secreted by the liver. Mass spectrometry (MS) is a useful tool that can detect variant TTRs in serum samples from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccf98e84b8d45cf795bda7667ac1e132
http://europepmc.org/articles/PMC6537225
http://europepmc.org/articles/PMC6537225
Autor:
Yohei Misumi, Akihiko Ueda, Toshiya Nomura, Taro Yamashita, Akihito Nagatoshi, Yasuteru Inoue, Masayoshi Tasaki, Hirotaka Matsui, Yukio Ando, Teruaki Masuda, Masamitsu Okada, Mitsuharu Ueda, Satoru Shinriki, Aito Isoguchi, Yihong Ma
Publikováno v:
Journal of the Neurological Sciences. 415:116931
To detect vascular Notch3 extracellular domain aggregates in CADASIL, we developed a novel dot-blot assay with both autopsy and biopsy skin samples. We obtained samples from 11 patients with CADASIL and 12 control patients, and we performed dot-blot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::526324f9b16ad3d4db0d1b041649ab88
https://doi.org/10.1016/j.jns.2020.116931
https://doi.org/10.1016/j.jns.2020.116931