Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Aitizaz Ul Ahsan"'
Publikováno v:
Journal of Molecular Neuroscience. 72:1259-1273
Valproic acid (VPA) induced rodent model of autism is a widely accepted and extensively used rodent model to investigate the pharmacotherapy against autism. But, to date, its validation, suitability, and applicability as a well defining autistic mode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::148353e131e22421556e6c109b83c695
https://doi.org/10.1007/s12031-022-02033-7
https://doi.org/10.1007/s12031-022-02033-7
Publikováno v:
Biomedical Research, Medicine, and Disease ISBN: 9781003220404
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b442a882dc7ba43044ce00b03bed67a
https://doi.org/10.1201/9781003220404-12
https://doi.org/10.1201/9781003220404-12
Autor:
Surbhi Kaushal, Era Seth, Priyanka Bamrara, Mani Chopra, Vijay Lakshmi Sharma, Aitizaz Ul Ahsan
Publikováno v:
Biologia. 76:1859-1872
The current study investigated the protective and antioxidant potential of Aegle marmelos leaf extract against Cadmium-induced alterations in hepatic and renal tissues of BALB/c mice. Cadmium (Cd) is known for its toxicity and induction of oxidative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40a711fb44cc16f81310bd6372c2b551
https://doi.org/10.1007/s11756-021-00733-w
https://doi.org/10.1007/s11756-021-00733-w
Publikováno v:
Molecular Neurobiology. 57:3589-3602
Deposition of an amyloid-β peptide is one of the first events in the pathophysiology of Alzheimer's disease (AD) and is clinically characterized by Aβ plaques, tau tangles, and behavioral impairments that lead to neuronal death. A substantial numbe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d3f157336e81f1224bb796f573cd331
https://doi.org/10.1007/s12035-020-01969-4
https://doi.org/10.1007/s12035-020-01969-4
Publikováno v:
Molecular Biology Reports. 46:5355-5369
Arsenic is well known genotoxicant which causes the excessive generation of reactive oxygen species (ROS) and inhibition of antioxidant enzyme systems leading to cell damage through the activation of oxidative sensitive signaling pathways. Epigalloca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b76c9e22116907b48f0641734ee435e
https://doi.org/10.1007/s11033-019-04991-5
https://doi.org/10.1007/s11033-019-04991-5
Publikováno v:
Molecular neurobiology. 57(8)
Deposition of an amyloid-β peptide is one of the first events in the pathophysiology of Alzheimer's disease (AD) and is clinically characterized by Aβ plaques, tau tangles, and behavioral impairments that lead to neuronal death. A substantial numbe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::98951ad2fa44ff6fc04ba9e70479e4d2
https://pubmed.ncbi.nlm.nih.gov/32542594
https://pubmed.ncbi.nlm.nih.gov/32542594
Autor:
Mani Chopra, Gurdarshan Singh, Aitizaz Ul Ahsan, Ajay Kumar, Mehak Gupta, Abubakar Wani, Ram A. Vishwakarma
Publikováno v:
Cytokine. 111:84-87
Deposition of amyloid-β in Alzheimer’s disease is accompanied by chronic inflammation, which involves raised levels of pro-inflammatory cytokines TNF-α, IL-6 and IL-1β. However, the role of Aβ1-42 in the inflammatory process, before it gets dep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fcdafd4b63777f5d5a025e875e95c4ee
https://doi.org/10.1016/j.cyto.2018.07.026
https://doi.org/10.1016/j.cyto.2018.07.026
Publikováno v:
Pesticide Biochemistry and Physiology. 179:104977
Chlorpyrifos (0,0-diethyl 0-(3,5,6-trichloro-2-pyridinyl)-phosphorothioate; (CPF)) is a widely used lipophilic organophosphorus insecticide that primarily manifests into central and peripheral nervous system toxicity. However, it is poorly investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47d2c795b699173fe4d189b98ba66902
https://doi.org/10.1016/j.pestbp.2021.104977
https://doi.org/10.1016/j.pestbp.2021.104977
Autor:
Sanjeev Kumar Digra, Abubakar Wani, Ajay Kumar, Pankaj Chibber, Surjeet Singh, Gurdarshan Singh, Mehak Gupta, Ram A. Vishwakarma, Aitizaz Ul Ahsan, Sandip B. Bharate, Mehboob Ali, Manish Datt
Publikováno v:
Toxicology and Applied Pharmacology. 423:115582
NLRP3 inflammasome is involved in several chronic inflammatory diseases. The inflammatory effect of the NLRP3 inflammasome is executed through IL-1β and IL-18. Therefore, IL-1β is one of the primary targets in chronic inflammatory conditions. Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf62c9f95149796f23d86839bbf30428
https://doi.org/10.1016/j.taap.2021.115582
https://doi.org/10.1016/j.taap.2021.115582
Alborixin clears amyloid-β by inducing autophagy through PTEN-mediated inhibition of the AKT pathway
Autor:
Sandip B. Bharate, Masroor Ahmad, Parduman R. Sharma, Abubakar Wani, Mehak Gupta, Ram A. Vishwakarma, Gurdarshan Singh, Fayaz Malik, Aabid Manzoor Shah, Ajay Kumar, Amal Kaddoumi, Parvaiz H. Qazi, Aitizaz Ul Ahsan
Imbalance in production and clearance of amyloid beta (Aβ) is the primary reason for its deposition in Alzheimer disease. Macroautophagy/autophagy is one of the important mechanisms for clearance of both intracellular and extracellular Aβ. Here, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11bf0439e6bc5f646a7ea523a8df34a8