Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Aiting Yang"'
Autor:
Ning Zhang, Xiaoning Wu, Wen Zhang, Yameng Sun, Xuzhen Yan, Anjian Xu, Qi Han, Aiting Yang, Hong You, Wei Chen
Publikováno v:
JHEP Reports, Vol 6, Iss 3, Pp 101014- (2024)
Background & Aims: Thrombospondin-2 (THBS2) expression is associated with liver fibrosis regardless of etiology. However, the role of THBS2 in the pathogenesis of liver fibrosis has yet to be elucidated. Methods: The in vivo effects of silencing Thbs
Externí odkaz:
https://doaj.org/article/bd15dfe9d9af4fb293030cb0387f26f5
Autor:
Huan Wang, Yushang Zhao, Yuhualei Pan, Aiting Yang, Changying Li, Song Wang, Zhao Dong, Mengyi Li, Songlin Wang, Zhongtao Zhang, Yanbing Zhu, Dong Zhang, Guangyong Sun
Publikováno v:
JHEP Reports, Vol 5, Iss 6, Pp 100726- (2023)
Background & Aims: Phospholipase D1 (PLD1), a phosphatidylcholine-hydrolysing enzyme, is involved in cellular lipid metabolism. However, its involvement in hepatocyte lipid metabolism and consequently non-alcoholic fatty liver disease (NAFLD) has not
Externí odkaz:
https://doaj.org/article/448b9192337445d08dc99429eec4749b
Autor:
Ping Wang, Min Cong, Tianhui Liu, Hufeng Xu, Lin Wang, Guangyong Sun, Aiting Yang, Dong Zhang, Jian Huang, Yameng Sun, Wenshan Zhao, Hong Ma, Jidong Jia, Hong You
Publikováno v:
Stem Cell Research & Therapy, Vol 8, Iss 1, Pp 1-11 (2017)
Abstract Background Although they are expandable in vitro, hepatic progenitors are immature cells and share many immunomarkers with hepatocellular carcinoma, raising potential concerns regarding maltransformation after transplantation. This study inv
Externí odkaz:
https://doaj.org/article/2a9d64d9f6314081b47d78aac71eb97f
Autor:
Ping Wang, Min Cong, Tianhui Liu, Aiting Yang, Guangyong Sun, Dong Zhang, Jian Huang, Shujie Sun, Jia Mao, Hong Ma, Jidong Jia, Hong You
Publikováno v:
Stem Cells International, Vol 2016 (2016)
Profibrogenesis cytokine, transforming growth factor- (TGF-) β1, induces hepatic progenitors experiencing epithelial to mesenchymal transition (EMT) to matrix synthesis cells, even tumor initiating cells. Our previous data found that epidermal growt
Externí odkaz:
https://doaj.org/article/e3df4206ecf2454d8614c2d6fb9319c6
Autor:
Ning Zhang, Aiting Yang, Wen Zhang, Hong Li, Anjian Xu, Xuzhen Yan, Qi Han, Bingqiong Wang, Hong You, Wei Chen
Publikováno v:
Hepatology Communications; Apr2024, Vol. 8 Issue 4, p1-13, 13p
Autor:
Ning Zhang, Xiaoning Wu, Wen Zhang, Xuzhen Yan, Anjian Xu, Qi Han, Aiting Yang, Wei Chen, Hong You
Thrombospondin-2 (THBS2) expression is closely associated with liver fibrosis regardless of etiology. However, the role of THBS2 in the pathogenesis of liver fibrosis has not been elucidated yet. Here we report THBS2 is predominantly expressed in act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38dbc9253c5925bceba20c46e94f9ce0
https://doi.org/10.21203/rs.3.rs-2921622/v1
https://doi.org/10.21203/rs.3.rs-2921622/v1
Autor:
Wei Chen, Yameng Sun, Shuyan Chen, Xiaodong Ge, Wen Zhang, Ning Zhang, Xiaoning Wu, Zhuolun Song, Hui Han, Romain Desert, Xuzhen Yan, Aiting Yang, Sukanta Das, Dipti Athavale, Natalia Nieto, Hong You
Publikováno v:
Hepatology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb1776ac1efbdbd3b8c689eae4f5122e
https://doi.org/10.1097/hep.0000000000000423
https://doi.org/10.1097/hep.0000000000000423
Publikováno v:
Journal of Clinical and Translational Hepatology. 10:577-588
Iron overload can contribute to the progression of nonalcoholic fatty liver disease (NAFLD) to nonalcoholic steatohepatitis (NASH). Hepcidin (Hamp), which is primarily synthesized in hepatocytes, is a key regulator of iron metabolism. However, the ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0f7edb8aaf52a3ed98c785b559c5e75
https://doi.org/10.14218/jcth.2021.00289
https://doi.org/10.14218/jcth.2021.00289
Autor:
Hufeng Xu, Hong You, Mengyang Zhang, Jidong Jia, Tao Huang, Xuzhen Yan, Aiting Yang, Xu Fan, Wei Chen, Weiyu Li
Publikováno v:
The FASEB Journal. 35
The role of LOXL1 in fibrosis via mediating ECM crosslinking and stabilization is well established; however, the role of hepatic stellate cells (HSCs)-specific LOXL1 in the development of fibrosis remains unknown. We generated HSCs-specific Loxl1-dep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c830c09da1460cc5b6f1d09bfcfe82ca
https://doi.org/10.1096/fj.202100374r
https://doi.org/10.1096/fj.202100374r
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 316:G744-G754
Elimination or suppression of causative factors can raise the possibility of liver fibrosis regression. However, different injurious stimuli will give fibrosis from somewhat different etiologies, which, in turn, may hamper the discovery of liver fibr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d160c34f030c836030fc3f4dd46cebdc
https://doi.org/10.1152/ajpgi.00339.2018
https://doi.org/10.1152/ajpgi.00339.2018