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pro vyhledávání: '"Aisulu Zhumagalieva"'
Autor:
Dmitry Dar'in, Anastasia Lepikhina, Aisulu Zhumagalieva, Tatyana A. Grigoreva, Daria S. Novikova, Vyacheslav G. Tribulovich, Olga Bakulina, Maxim A. Gureyev, A. V. Garabadzhiu, Mikhail Krasavin, Maria Chizhova, Gleb S. Ivanov
Publikováno v:
Bioorganic & Medicinal Chemistry. 26:2651-2673
Five lactam chemotypes amenable by the Castagnoli-Cushman reaction of imines and cyclic anhydrides have been investigated for their ability to activate p53 tumor suppressing transcription factor thus induce apoptosis in p53+ cancer cells. A virtual l