Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Aisling O'Dowd"'
Autor:
Michael G Jobling, Steven T Poole, Fatima Rasulova-Lewis, Aisling O'Dowd, Annette L McVeigh, Amit Balakrishnan, Stephanie A Sincock, Michael G Prouty, Randall K Holmes, Stephen J Savarino
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0230138 (2020)
Surface-expressed colonization factors and their subunits are promising candidates for inclusion into a multivalent vaccine targeting enterotoxigenic Escherichia coli (ETEC), a leading cause of acute bacterial diarrhea in developing regions. However,
Externí odkaz:
https://doaj.org/article/4dcad7b76d7841d48926d04c2ed1df9f
Autor:
Yang Liu, Milton Maciel, Aisling O’Dowd, Steven T. Poole, Julianne E. Rollenhagen, Irina V. Etobayeva, Stephen J. Savarino
Publikováno v:
Microorganisms, Vol 9, Iss 8, p 1646 (2021)
Enterotoxigenic Escherichia coli (ETEC) is a leading cause of diarrhea in travelers and children in resource-limited countries. ETEC colonization factors, fimbrial tip adhesins and enterotoxins are key virulence factors, and thus have been studied as
Externí odkaz:
https://doaj.org/article/6aac80f5dd714a7da271b88979421de2
Autor:
Stephen J. Savarino, Michael G. Prouty, Julianne E. Rollenhagen, Greg Glenn, Larry Ellingsworth, Jing Hui Tian, Steven T. Poole, Colleen M. Woods, Mimi Guebre-Xabier, Aisling O’Dowd
Publikováno v:
Vaccine. 37:6134-6138
dscCfaE is a recombinant form of the CFA/I tip adhesin CfaE, expressed by a large proportion of enterotoxigenic E. coli (ETEC). It is highly immunogenic by the intranasal route in mice and Aotus nancymaae, protective against challenge with CFA/I+ ETE
Autor:
Chad K. Porter, David R. Tribble, Barbara DeNearing, Stephen J. Savarino, Robin McKenzie, Shannon L. Grahek, Aisling O'Dowd, Stephanie A. Sincock, Carl Brinkley, Steven T. Poole, Joseph H. Crabb, Colleen M. Woods, A. Louis Bourgeois, Hye Kim
Publikováno v:
The Journal of Infectious Diseases. 220:505-513
BackgroundEnterotoxigenic Escherichia coli (ETEC) commonly cause diarrhea in children living in developing countries and in travelers to those regions. ETEC are characterized by colonization factors (CFs) that mediate intestinal adherence. We assesse
Autor:
Julianne E. Rollenhagen, Nereyda Espinoza, Gladys Nunez, Aisling O'Dowd, Eric R. Hall, Stephen J. Savarino
Publikováno v:
Infect Immun
Enterotoxigenic Escherichia coli (ETEC) is a common cause of diarrheal illness in the military, travelers, and children living in low- to middle-income countries. Increased antibiotic resistance, the absence of a licensed vaccine, and the lack of bro
Autor:
Colleen M. Woods, Michael J. Gregory, Stephen J. Savarino, Milton Maciel, Michael G. Prouty, Steven T. Poole, Julianne E. Rollenhagen, Stephanie A. Sincock, Ryan C. Maves, Michael G. Jobling, Randall K. Holmes, Annette L. McVeigh, Aisling O'Dowd
Publikováno v:
Infect Immun
Recent efforts to develop an enterotoxigenic Escherichia coli (ETEC) vaccine have focused on the antigenically conserved tip adhesins of colonization factors. We showed previously that intranasal immunization with dsc(19)CfaE, a soluble variant of th
Autor:
Randall K. Holmes, Stephen J. Savarino, Steven T. Poole, Stephanie A. Sincock, Aisling O’Dowd, Michael G. Prouty, Amit Balakrishnan, Michael G. Jobling, Annette L. McVeigh, Fatima Rasulova-Lewis
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0230138 (2020)
PLoS ONE
PLoS ONE
Surface-expressed colonization factors and their subunits are promising candidates for inclusion into a multivalent vaccine targeting enterotoxigenic Escherichia coli (ETEC), a leading cause of acute bacterial diarrhea in developing regions. However,
Autor:
Irina V. Etobayeva, Stephen J. Savarino, Milton Maciel, Julianne E. Rollenhagen, Yang Liu, Steven T. Poole, Aisling O’Dowd
Publikováno v:
Microorganisms, Vol 9, Iss 1646, p 1646 (2021)
Microorganisms
Volume 9
Issue 8
Microorganisms
Volume 9
Issue 8
Enterotoxigenic Escherichia coli (ETEC) is a leading cause of diarrhea in travelers and children in resource-limited countries. ETEC colonization factors, fimbrial tip adhesins and enterotoxins are key virulence factors, and thus have been studied as
Autor:
Chad K. Porter, Stephanie A. Sincock, Stephen J. Savarino, Joseph H. Crabb, Shannon L. Grahek, Colleen M. Woods, Joyce A. Cantrell, David R. Tribble, Robin McKenzie, A. Louis Bourgeois, Aisling O'Dowd, Carl Brinkley, Barbara DeNearing, Hye Kim, Steven T. Poole
Publikováno v:
The Journal of Infectious Diseases. 216:7-13
Background Tip-localized adhesive proteins of bacterial fimbriae from diverse pathogens confer protection in animal models, but efficacy in humans has not been reported. Enterotoxigenic Escherichia coli (ETEC) commonly elaborate colonization factors
Autor:
Ryan C. Maves, Michael G. Prouty, Aisling O'Dowd, Nereyda Espinoza, Eric W. Hall, Julianne E. Rollenhagen, Franca R. Jones, Gladys Nunez, Stephen J. Savarino
The establishment of an animal model that closely approximates enterotoxigenic Escherichia coli (ETEC) disease in humans is critical for the development and evaluation of vaccines against this enteropathogen. Here, we evaluated the susceptibility of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa74ce3353636ba78b41975fef8fa9e7
https://europepmc.org/articles/PMC6346130/
https://europepmc.org/articles/PMC6346130/