Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Aisling O'Brien"'
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
Following a one medicine approach, the development of regenerative therapies for human patients leads to innovative treatments for animals, while pre-clinical studies on animals provide knowledge to advance human medicine. Among many different biolog
Externí odkaz:
https://doaj.org/article/56f26d93b3dd4363acdd96a61ea15858
Targeting JAK-STAT Signalling Alters PsA Synovial Fibroblast Pro-Inflammatory and Metabolic Function
Autor:
Aisling O’Brien, Megan Mary Hanlon, Viviana Marzaioli, Siobhan C. Wade, Keelin Flynn, Ursula Fearon, Douglas J. Veale
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
ObjectivesPsoriatic arthritis (PsA) is a chronic inflammatory disease associated with psoriasis. Janus Kinase inhibitors (JAKi) have emerged as an encouraging class of drugs for the treatment of PsA. Here, we compare the effect of four JAKi on primar
Externí odkaz:
https://doaj.org/article/d6653fec4c3b4650bfc9bbc9e205e170
Autor:
Yicheng Ding, Aisling O'Brien, Berta Marcó de la Cruz, Meimei Yang, Yin Lu, Xiaohong Qian, Guangming Yang, Veronica McInerney, Janusz Krawczyk, Sally A. Lynch, Linda Howard, Nicholas M. Allen, Timothy O'Brien, Louise Gallagher, Sanbing Shen
Publikováno v:
Stem Cell Research, Vol 53, Iss , Pp 102254- (2021)
NRXN1 deletions are commonly found in autism spectrum disorder (ASD) and other neurodevelopmental/neuropsychiatric disorders. Derivation of induced pluripotent stem cells (iPSCs) from different diseases involving different deletion regions are essent
Externí odkaz:
https://doaj.org/article/f9e86826ed454b82bf011cf698ad984b
Autor:
Yicheng Ding, Aisling O'Brien, Berta Marcó de la Cruz, Meimei Yang, Jacqueline Fitzgerald, Guangming Yang, Weidong Li, Veronica McInerney, Janusz Krawczyk, Sally A. Lynch, Linda Howard, Nicholas M. Allen, Timothy O'Brien, Louise Gallagher, Sanbing Shen
Publikováno v:
Stem Cell Research, Vol 52, Iss , Pp 102222- (2021)
NRXN1 encodes thousands of splicing variants categorized into long NRXN1α, short NRXN1β and extremely short NRXN1γ, which exert differential roles in neuronal excitation/inhibition. NRXN1α deletions are common in autism spectrum disorder (ASD) an
Externí odkaz:
https://doaj.org/article/e838199a5f194dc29c0e8c4705086fbb
Publikováno v:
Clinical Biochemistry. 116:113-119
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5eb75f529a0504e818846c6edf23bb99
https://doi.org/10.1016/j.clinbiochem.2023.04.008
https://doi.org/10.1016/j.clinbiochem.2023.04.008
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 22:e34-e40
In recent years, the life expectancy of Multiple Myeloma (MM) patients has substantially improved, but this cancer remains incurable with increasing incidence in the developed world. Most MM patients will eventually relapse due to residual drug-resis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d237f80cce5e3190f8984109f4b0af76
https://doi.org/10.1016/j.clml.2021.07.032
https://doi.org/10.1016/j.clml.2021.07.032
Targeting JAK-STAT Signalling Alters PsA Synovial Fibroblast Pro-Inflammatory and Metabolic Function
Autor:
M. Hanlon, Ursula Fearon, Aisling O’Brien, Keelin Flynn, S. Wade, Douglas J. Veale, Viviana Marzaioli
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, Vol 12 (2021)
ObjectivesPsoriatic arthritis (PsA) is a chronic inflammatory disease associated with psoriasis. Janus Kinase inhibitors (JAKi) have emerged as an encouraging class of drugs for the treatment of PsA. Here, we compare the effect of four JAKi on primar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b55091602cd26eaa15b53977c6f305f5
https://pubmed.ncbi.nlm.nih.gov/34248953
https://pubmed.ncbi.nlm.nih.gov/34248953
Cartilage is a tissue of critical importance in development, postnatal growth and in articulation. It is a highly specialized tissue comprising distinct populations of chondrocytes and an abundant extracellular matrix rich in collagens and proteoglyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4489fc628ed6ec45879e59532d8b7133
https://doi.org/10.1016/b978-0-12-823884-4.00010-9
https://doi.org/10.1016/b978-0-12-823884-4.00010-9
Autor:
Blanca I. Aldana, J.R. Allred, Andy Y. An, Beverlie Baquir, William B. Barrell, Frank Barry, Anna Biason-Lauber, B.R. Blazar, Aaron C. Brown, John C. Butts, Yu Chen, Aurelie de Rus Jacquet, Kristine K. Freude, Xiugong Gao, Tae-Un Han, Robert E.W. Hancock, Amy H.Y. Lee, Yongxing James Liu, Karen J. Liu, Julieta Martino, Anne H. Monsoro-Burq, Aisling O'Brien, Chloé A. Paka, Daniel Rodríguez Gutiérrez, Vinicius Rosa, Claudia Salcedo, Richard Sam, Ellen Sidransky, Francisco Silva, Robert L. Sprando, Helle S. Waagepetersen, R.L. Williams, Maojia Xu, Jeffrey J. Yourick
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::737f033d0fd0c1d1e46e0e48b073bc4c
https://doi.org/10.1016/b978-0-12-823884-4.01002-6
https://doi.org/10.1016/b978-0-12-823884-4.01002-6
Autor:
Nicholas M. Allen, Jacqueline Fitzgerald, Guangming Yang, Aisling O'Brien, Louise Gallagher, Janusz Krawczyk, Sally Ann Lynch, Yicheng Ding, Sanbing Shen, Weidong Li, Veronica McInerney, Linda Howard, Meimei Yang, Timothy O'Brien, Berta Marcó de la Cruz
Publikováno v:
Stem Cell Research, Vol 52, Iss, Pp 102222-(2021)
NRXN1 encodes thousands of splicing variants categorized into long NRXN1α, short NRXN1β and extremely short NRXN1γ, which exert differential roles in neuronal excitation/inhibition. NRXN1α deletions are common in autism spectrum disorder (ASD) an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f37242a9ced12b7bad6bbae846b71554
https://pubmed.ncbi.nlm.nih.gov/33578364
https://pubmed.ncbi.nlm.nih.gov/33578364